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PUBLISHED PAPERS

PRESSURE
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Mouse / Rat
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Rabbit / Sm Animal
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Pig / Sheep / Dog
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Other Lg Animal
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Human
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In Vitro

PRESSURE VOLUME
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Mouse / Rat
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Rabbit / Sm Animal
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Pig / Sheep / Dog
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Human
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In Vitro

ELECTrophysiology
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Mouse

OTHER APPLICATIONS
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All Subjects

  Published Papers : Pressure - Pig / Sheep / Dog

Pressure - Pig / Sheep / Dog

If you would like to submit a publication for posting, please email us at papers@millarmail.com

AUTHORS TITLE JOURNAL MILLAR EQPT. SUBJECT application
Zhou L, Huang H, Yuan CL, Keung W, Lopaschuk GD, Stanley WC Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation Am J Physiol Heart Circ Physiol, Feb 2008; 294: H954 - H960 high-fidelity pressure transducer  pig acetyl-CoA carboxylase; AMP-activated protein kinase; exercise; fatty acids; heart; mitochondria
Kawase Y, Ly HQ, Prunier F, Lebeche D, YShi Y, Jin H, Hadri L, Yoneyama R, Hoshino K, Takewa Y, Sakata S, Peluso R, Zsebo K, Gwathmey JK, Tardif J-C, Tanguay J-F, Hajjar RJ Reversal of Cardiac Dysfunction After Long-Term Expression of SERCA2a by Gene Transfer in a Pre-Clinical Model of Heart Failure J. Am. Coll. Cardiol., March 18, 2008; 51: 1112 - 1119 6-F Millar MIKRO-TIP catheter pig mitral regurgitation
Pandalai PK, McLean KM, Bulcao CF, Duffy JY, D'Souza KM, Merrill WH, Pearl JM, Akhter SA Acute β-blockade prevents myocardial β-adrenergic receptor desensitization and preserves early ventricular function after brain death J. Thorac. Cardiovasc. Surg., April 2008; 135: 792 - 798 Pressure transducer-tipped 2F or 3F catheters pig adenylate cyclase; heart failure; preload recruitable stroke work
Penny DJ, Mynard JP, Smolich JJ Aortic wave intensity analysis of ventricular-vascular interaction during incremental dobutamine infusion in adult sheep Am J Physiol Heart Circ Physiol, Jan 2008; 294: H481 - H489 MPC-500, TCB-500 sheep hemodynamics; wave propagation; arterial circulation; blood velocity
Beeri R, Yosefy C, Guerrero JL, Nesta F, Abedat S, Chaput M, del Monte F, Handschumacher MD, Stroud R,  Sullivan S, Pugatsch T, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA Mitral Regurgitation Augments Post-Myocardial Infarction Remodeling: Failure of Hypertrophic Compensation J. Am. Coll. Cardiol., January 29, 2008; 51: 476 - 486 high-fidelity micromanometer-tipped catheter  sheep dilated heart failure
Notomi Y, Popovic ZB, Yamada H, Wallick DW, Martin MG, Oryszak SJ, Shiota T, Greenberg NL, Thomas JD Ventricular untwisting: a temporal link between left ventricular relaxation and suction Am J Physiol Heart Circ Physiol, Jan 2008; 294: H505 - H513 triple-sensor Millar catheter (40 mm, distal to middle; and 20 mm, middle to proximal; Millar Instruments) dog diastole; relaxation; suction; torsion
Hong T-T, Huang J, Barrett TD, Lucchesi BR Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis Am J Physiol Heart Circ Physiol, Jan 2008; 294: H145 - H155 Millar blood pressure catheter transducer  dog inflammation; vascular reactivity
Banfor PN, Preusser LC, Campbell TJ, Marsh KC, Polakowski JS, Reinhart GA, Cox BF, Fryer RM Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs Am J Physiol Heart Circ Physiol, Jan 2008; 294: H238 - H248 SPC-770, 7F dog cardiac contractility, vasdilation 
Rao L, Ling Y, He R, Gilbert AL, Frangogiannis NG, Wang J, Nagueh SF, Khoury DS Integrated multimodal-catheter imaging unveils principal relationships among ventricular electrical activity, anatomy, and function Am J Physiol Heart Circ Physiol, Feb 2008; 294: H1002 - H1009 SPC-350 dog electrophysiology; myocardial infarction; noncontact mapping
Pirat B, Khoury DS, Hartley CJ, Tiller L, Rao L, Schulz DG, Nagueh SF, Zoghbi WA A Novel Feature-Tracking Echocardiographic Method for the Quantitation of Regional Myocardial Function: Validation in an Animal Model of Ischemia-Reperfusion J. Am. Coll. Cardiol., February 12, 2008; 51: 651 - 659 SPC-350 dog velocity vector imaging
Desai KV, Laine GA, Stewart RH, Cox Jr CS, Quick CM, Allen SJ, Fischer UM Mechanics of the left ventricular myocardial interstitium: effects of acute and chronic myocardial edema Am J Physiol Heart Circ Physiol, Jun 2008; 294: H2428 - H2434 solid-state pressure transducers dog left ventricular chamber compliance; compliance resetting; edemagenic gain
Gross GJ, Gauthier KM, Moore J, Falck JR, Hammock BD, Campbell WB, Nithipatikom K Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart Am J Physiol Heart Circ Physiol, Jun 2008; 294: H2838 - H2844 SPC-770, double-tipped Millar dog cytochrome P-450 epoxygenase; epoxyeicosatrienoic acids; soluble epoxide hydrolase; ATP-sensitive potassium channel opener
Timmers L, Sluijter JPG, Verlaan CWJ, Steendijk P, Cramer MJ, Emons M, Strijder C, Gründeman PF, Sze SK, Hua L, Piek JJ, Borst C, Pasterkamp G, Kleijn DPV Cyclooxygenase-2 Inhibition Increases Mortality, Enhances Left Ventricular Remodeling, and Impairs Systolic Function After Myocardial Infarction in the Pig Circulation, Jan 2007; 115: 326 - 332 pressure-tipped Millar catheter pig myocardial infarction • heart failure • remodeling • enzymes
Axelsson M, Dang Q, Pitsillides K, Munns S, Hicks J, Kassab GS A novel, fully implantable, multichannel biotelemetry system for measurement of blood flow, pressure, ECG, and temperature J Appl Physiol, Mar 2007; 102: 1220 - 1228 1 mm in diameter, 3F, pig, alligator chronic measurements; Doppler flow; telemetry; swine; alligator
Schmidt MR, Smerup M, Konstantinov IE, Shimizu M, Li J, Cheung M, White PA, Kristiansen SB, Sorensen K, Dzavik V, Redington AN, Kharbanda RK Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning Am J Physiol Heart Circ Physiol, Apr 2007; 292: H1883 - H1890 integrated micromanometer, PVAN pig remote preconditioning; cardioprotection
Kotani Y, Ishino K, Osaki S, Honjo O, Suezawa T, Kanki K, Yutani C, Sano S Efficacy of MCI-186, a free-radical scavenger and antioxidant, for resuscitation of nonbeating donor hearts J. Thorac. Cardiovasc. Surg., June 2007; 133: 1626 - 1632 3F pressure-tip catheter pig transplantation
Cortina C, Bermejo J, Yotti R, Desco MM, Rodríguez-Pérez D, Antoranz C, Rojo-Álvarez JL, Garcia D, García-Fernández MA, Fernández-Avilés F Noninvasive Assessment of the Right Ventricular Filling Pressure Gradient Circulation, Aug 2007; 116: 1015 - 1023 Micromanometer catheters pig RV driving filling force 
Shuros AC, Salo RW, Florea VG, Pastore J, Kuskowski MA, Chandrashekhar Y, Anand IS Ventricular Preexcitation Modulates Strain and Attenuates Cardiac Remodeling in a Swine Model of Myocardial Infarction Circulation, Sep 2007; 116: 1162 - 1169 LV pressures (Millar Instruments) pig myocardial infarction • remodeling • heart failure • myocardial contraction • electrical stimulation
Berberian G, Quinn TA, Cabreriza SE, Kenny JS, Garofalo CA, Weinberg AD, Spotnitz HM Left ventricular pacing site and timing optimization during biventricular pacing using a multielectrode patch in pigs J. Thorac. Cardiovasc. Surg., September 2007; 134: 574 - 578 5F micromanometer catheters pig Dual-chamber mode biventricular pacing
Ewy GA, Zuercher M, Hilwig RW, Sanders AB, Berg RA, Otto CW, Hayes MM, Kern KB Improved Neurological Outcome With Continuous Chest Compressions Compared With 30:2 Compressions-to-Ventilations Cardiopulmonary Resuscitation in a Realistic Swine Model of Out-of-Hospital Cardiac Arrest Circulation, Nov 2007; 116: 2525 - 2530 MPC-500 pig ventilations-to-chest-compression algorithm. CPR
Ghanta RK, Rangaraj A, Umakanthan R, Lee L, Laurence RG, Fox JA, Bolman III RM, Cohn LH, Chen FY Adjustable, Physiological Ventricular Restraint Improves Left Ventricular Mechanics and Reduces Dilatation in an Ovine Model of Chronic Heart Failure Circulation, Mar 2007; 115: 1201 - 1210 High-fidelity micromanometers sheep restraint level
Flewitt JA, Hobson TN, Wang Jr J, Johnston CR, Shrive NG, Belenkie I, Parker KH, Tyberg JV Wave intensity analysis of left ventricular filling: application of windkessel theory Am J Physiol Heart Circ Physiol, Jun 2007; 292: H2817 - H2823 8-Fr, model PC-480, SPR-524 dog transmitral flow; mitral velocity; E wave; diastolic suction
Joudinaud TM, Kegel CL, Flecher EM, Weber PA, Lansac E, Hvass U, Duran CMG The papillary muscles as shock absorbers of the mitral valve complex. An experimental study Eur. J. Cardiothorac. Surg., July 2007; 32: 96 - 101 TCB 600 and MIKRO-TIP pressure transducers, model 510 sheep Anatomy • Mitral valve • Regurgitation • Papillary muscles • Surgery
Carlhäll C, Kindberg K, Wigström L, Daughters GT, Miller DC, Karlsson M, Ingels Jr NB Contribution of mitral annular dynamics to LV diastolic filling with alteration in preload and inotropic state Am J Physiol Heart Circ Physiol, Sep 2007; 293: H1473 - H1479 SPC-500 sheep diastolic function; inotropic augmentation; mitral annular excursion; preload reduction; regional left ventricular filling properties
Beeri R, Yosefy C, Guerrero JL, Abedat S, Handschumacher MD, Stroud RE, Sullivan S, Chaput M, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA Early Repair of Moderate Ischemic Mitral Regurgitation Reverses Left Ventricular Remodeling: A Functional and Molecular Study Circulation, Sep 2007; 116: I-288 - I-293 high-fidelity micromanometer-tipped catheter  sheep mitral valve • myocardial infarction • regurgitation • remodeling • surgery
Hung J, Chaput M, Guerrero JL, Handschumacher MD, Papakostas L, Sullivan S, Solis J, Levine RA Persistent Reduction of Ischemic Mitral Regurgitation by Papillary Muscle Repositioning: Structural Stabilization of the Papillary Muscle–Ventricular Wall Complex Circulation, Sep 2007; 116: I-259 - I-263 micromanometer-tipped Millar catheter  sheep mitral regurgitation • left ventricular remodeling
Mau J, Menzie S, Ward M, Bundgaard H, Hunyor S Time-dependent response of both ventricles after septal ablation: Implications for biventricular support after left ventricular assist device placement J. Thorac. Cardiovasc. Surg., September 2007; 134: 579 - 586 5F Millar catheter-tip pressure transducer sheep percutaneous transluminal septal myocardial ablation
Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Acevedo-Bolton G, Guttman MA, Ozturk C, McVeigh ER, Saloner DA, Wallace AW, Ratcliffe MB Endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm increases systolic circumferential shortening in sheep J. Thorac. Cardiovasc. Surg., October 2007; 134: 1017 - 1024 SPC-350 sheep Dor procedure
Maruo T, Nakatani S, Jin Y, Uemura K, Sugimachi M, Ueda-Ishibashi H, Kitakaze M, Ohe T, Sunagawa K, Miyatake K Evaluation of transmural distribution of viable muscle by myocardial strain profile and dobutamine stress echocardiography Am J Physiol Heart Circ Physiol, Feb 2007; 292: H921 - H927 MPC-500 dog echocardiography
Jin Y-T, Hasebe N, Matsusaka T, Natori S, Ohta T, Tsuji S, Kikuchi K Magnesium attenuates isoproterenol-induced acute cardiac dysfunction and β-adrenergic desensitization Am J Physiol Heart Circ Physiol, Mar 2007; 292: H1593 - H1599 SPC-350 dog calcium overload; free radical; dog, left ventricular; tau
Hobson TN, Flewitt JA, Belenkie I, Tyberg JV Wave intensity analysis of left atrial mechanics and energetics in anesthetized dogs Am J Physiol Heart Circ Physiol, Mar 2007; 292: H1533 - H1540 2-F micromanometer dog hemodynamics; left atrium; A wave; Ar wave; Doppler echocardiography
Wang J, Khoury DS, Thohan V, Torre-Amione G, Nagueh SF Global Diastolic Strain Rate for the Assessment of Left Ventricular Relaxation and Filling Pressures Circulation, Mar 2007; 115: 1376 - 1383 7F dog Global SRIVR by 2-dimensional speckle tracking
Fukuoka M, Nonaka M, Masuyama S, Shimamoto T, Tambara K, Yoshida H, Ikeda T, Komeda M Chordal "translocation" for functional mitral regurgitation with severe valve tenting: An effort to preserve left ventricular structure and function J. Thorac. Cardiovasc. Surg., April 2007; 133: 1004 - 1011 MPC-500 dog chordae tendineae
Hori Y, Kano T, Hoshi F, Higuchi S Relationship between tissue Doppler-derived RV systolic function and invasive hemodynamic measurements Am J Physiol Heart Circ Physiol, Jul 2007; 293: H120 - H125 3.5-Fr micromanometer-tipped catheter dog dog; right ventricle; systolic myocardial velocity; tissue Doppler imaging
Coppola BA, Covell JW, McCulloch AD, Omens JH Asynchrony of ventricular activation affects magnitude and timing of fiber stretch in late-activated regions of the canine heart Am J Physiol Heart Circ Physiol, Jul 2007; 293: H754 - H761 8-Fr pigtail micromanometer catheter with a lumen dog ventricular pacing; mechanical activation; fiber stretch; dyssynchrony
Akar FG, Nass RD, Hahn S, Cingolani E, Shah M, Hesketh GG, DiSilvestre D,  Tunin RS, Kass DA, Tomaselli GF Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure Am J Physiol Heart Circ Physiol, Aug 2007; 293: H1223 - H1230 Millar catheter dog electrical remodeling; connexin; arrhythmias
Jaber WA, Lam CSP, Meyer DM, Redfield MM Revisiting methods for assessing and comparing left ventricular diastolic stiffness: impact of relaxation, external forces, hypertrophy, and comparators Am J Physiol Heart Circ Physiol, Nov 2007; 293: H2738 - H2746 high-fidelity micromanometer-tipped catheter  dog hemodynamics; heart failure; methods; pericardium
Johnson L, Kim HK, Tanabe M, Gorcsan J, Schwartzman D, Shroff SG, Pinsky MR Differential effects of left ventricular pacing sites in an acute canine model of contraction dyssynchrony Am J Physiol Heart Circ Physiol, Nov 2007; 293: H3046 - H3055 MPC-500 dog cardiac resynchronization therapy; left ventricular global performance; myocardial strain; tissue Doppler imaging
Wang J, Khoury DS, Yue Y, Torre-Amione G, Nagueh SF Left Ventricular Untwisting Rate by Speckle Tracking Echocardiography Circulation, Nov 2007; 116: 2580 - 2586 7F  dog dobutamine and esmolol infusion
da Cunha DNQ, Hamlin RL, Billman GE, Carnes CA n-3 (omega-3) polyunsaturated fatty acids prevent acute atrial electrophysiological remodeling  British Journal of Pharmacology 150, 281 - 285 (01 Feb 2007) SPC-350 dog antiarrhythmic agents, atrial function, ECG, atrial fibrillation, n-3 polyunsaturated fatty acids, n-6 polyunsaturated fatty acids
 
Weinstock J, Maron BJ, Song C, Mane PP, Estes NAM, Link MS Failure of Commercially Available Chest Wall Protectors to Prevent Sudden Cardiac Death Induced by Chest Wall Blows in an Experimental Model of Commotio Cordis PEDIATRICS (doi:10.1542/peds.2005-1270) Millar Mikrotip pig death • sudden cardiac • arrhythmia • ventricular fibrillation • pediatrics • commotio cordis • athletes
Okere IC, McElfresh TA, Brunengraber DZ, Martini W, Sterk JP, Huang H, Chandler MP, Brunengraber H, Stanley WC Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion J Appl Physiol, Jan 2006; 100: 76 - 82 high-fidelity manometer-tipped catheter pig anaplerosis; fatty acids; heart; metabolism; mitochondria; pyruvate dehydrogenase
Schwartz LM, Lagranha CJ Ischemic postconditioning during reperfusion activates Akt and ERK without protecting against lethal myocardial ischemia-reperfusion injury in pigs Am J Physiol Heart Circ Physiol, Mar 2006; 290: H1011 - H1018 SPC-780C pig swine; signal transduction; extracellular signal-regulated kinase 1/2; infarction; ischemic preconditioning
Berberian G, Quinn TA, Cabreriza SE, Garofalo CA, Barrios DM, Weinberg AD, Spotnitz HM Load dependence of cardiac output in biventricular pacing: Left ventricular volume overload in pigs J. Thorac. Cardiovasc. Surg., Mar 2006; 131: 666 - 670 5F micromanometer catheters pig perioperative temporary biventricular pacing
Weinstock J, Maron BJ, Song C, Mane PP, Estes III NAM, Link MS Failure of Commercially Available Chest Wall Protectors to Prevent Sudden Cardiac Death Induced by Chest Wall Blows in an Experimental Model of Commotio Cordis Pediatrics, Apr 2006; 117: e656 - e662 Millar catheter pig death • sudden cardiac • arrhythmia • ventricular fibrillation • pediatrics • commotio cordis • athletes
Barrabés JA, Garcia-Dorado D, Agulló L, Rodríguez-Sinovas A, Padilla F, Trobo L, Soler-Soler J Intracoronary infusion of Gd3+ into ischemic region does not suppress phase Ib ventricular arrhythmias after coronary occlusion in swine Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2344 - H2350 micromanometer-tipped catheter pig ischemia; stretch; mechanoelectrical coupling; ventricular dilation; sudden death
Quinn TA, Berberian G, Cabreriza SE, Maskin LJ, Weinberg AD, Holmes JW, Spotnitz HM Effects of sequential biventricular pacing during acute right ventricular pressure overload Am J Physiol Heart Circ Physiol, Nov 2006; 291: H2380 - H2387 Solid-state pressure transducer catheters 5-Fr pig ventricular mechanics; interventricular synchrony; cardiac output; perioperative pacing; cardiac resynchronization therapy
Tozzi P, Hayoz D, Sinisclachi G, von Segesser LK VERMEIDUNG VON MYOINTIMALER HYPERPLASIE IN EINEM PULMONALARTERIELLEN NIEDERFLUSSANASTOMOSEMODELL BEIM SCHWEIN SwissPerfusion, November 2006 MPC-500 schwein Gefäßanastomosen, Intima-Hyperplasie, Anastomosen-Stenose, Wandscherkräfte
Guccione JM, Walker JC, Beitler JR, Moonly SM, Zhang P, Guttman MA, Ozturk C, McVeigh ER, Wallace AW, Saloner DA, Ratcliffe MB The effect of anteroapical aneurysm plication on end-systolic three-dimensional strain in the sheep: A magnetic resonance imaging tagging study J. Thorac. Cardiovasc. Surg., Mar 2006; 131: 579 - 586 SPC-320 sheep left ventricular aneurysm
Langer F, Rodriguez F, Cheng A, Ortiz S, Nguyen TC, Zasio MK, Liang D, Daughters GT, Ingels NB, Miller DC Posterior mitral leaflet extension: An adjunctive repair option for ischemic mitral regurgitation? J. Thorac. Cardiovasc. Surg., Apr 2006; 131: 868 - 877 SPC-500 sheep restricted leaflet (Carpentier type IIIb) systolic closing motion
Leshnower BG, Sakamoto H,Zeeshan A, Parish LM, Hinmon R, Plappert T, Jackson BM, Gorman III JH, Gorman RC Role of acetaminophen in acute myocardial infarction Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2424 - H2431 SPC-350S, SPR-524 sheep, rabbit reperfusion therapy; nonsteroidal anti-inflammatory drugs; sonomicrometry array localization
Messas E, Yosefy C, Chaput M, Guerrero JL, Sullivan S, Menasché P, Carpentier A, Desnos M, Hagege AA, Vlahakes GJ, Levine RA Chordal Cutting Does Not Adversely Affect Left Ventricle Contractile Function Circulation, Jul 2006; 114: I-524 - I-528 5-F micromanometer-tipped Millar catheter sheep chordae • echocardiography • mitral valve • regurgitation
Kilic A, Li T, Nolan TDC,Nash JR, Li S, Prastein DJ, Schwartzbauer G,  Moainie SL, Yankey GK, DeFilippi C, Wu Z, Griffith BP Strain-related regional alterations of calcium-handling proteins in myocardial remodeling J. Thorac. Cardiovasc. Surg., Oct 2006; 132: 900 - 908 SPC-350 sheep postinfarction cardiac remodeling
Sakamoto H, Parish LM, Hamamoto H, Enomoto Y, Zeeshan A, Plappert T, Jackson BM, St. John-Sutton MG, Gorman RC, Gorman III JH Effects of hemodynamic alterations on anterior mitral leaflet curvature during systole J. Thorac. Cardiovasc. Surg., Dec 2006; 132: 1414 - 1419 SPC-350 sheep phenylephrine hydrochloride infusion
Wang J-J, Flewitt JA, Shrive NG, Parker KH, Tyberg JV Systemic venous circulation. Waves propagating on a windkessel: relation of arterial and venous windkessels to systemic vascular resistance Am J Physiol Heart Circ Physiol, Jan 2006; 290: H154 - H162 2F dog systemic circulation
Wu G, Du Z, Hu C, Zheng Z, Zhan C, Ma H, Fang D,  Ahmed KT, Laham RJ, Hui JCK, Lawson WE Angiogenic effects of long-term enhanced external counterpulsation in a dog model of myocardial infarction Am J Physiol Heart Circ Physiol, Jan 2006; 290: H248 - H254 pressure transducer catheter dog angiogenesis; collateral circulation; growth factors; infarction; ventricular function
Hong T-T, Huang J, Lucchesi BR Effect of thrombolysis on myocardial injury: recombinant tissue plasminogen activator vs. alfimeprase Am J Physiol Heart Circ Physiol, Mar 2006; 290: H959 - H967 Millar Mikro-Tip pressure-sensitive transducer catheter dog myocardium; reperfusion injury; thrombolytic agents
Verbeek XAAM, Auricchio A, Yu Y,  Ding J, Pochet T,  Vernooy K,  Kramer A, Spinelli J, Prinzen FW Tailoring cardiac resynchronization therapy using interventricular asynchrony. Validation of a simple model Am J Physiol Heart Circ Physiol, Mar 2006; 290: H968 - H977 SPC-780C dog bundle-branch block; conduction; heart failure; pacing; ventricles
Yong-Mei Cha, Petras P. Dzeja, Margaret M. Redfield, Win K. Shen, and Andre Terzic Bioenergetic protection of failing atrial and ventricular myocardium by vasopeptidase inhibitor omapatrilat Am J Physiol Heart Circ Physiol, Apr 2006; 290: H1686 - H1692 high-fidelity Millar catheter dog atria; ventricle; adenylate kinase; creatine kinase; energy metabolism; heart failure
Popovic ZB, Prasad A, Garcia MJ, Arbab-Zadeh A, Borowski A, Dijk E, Greenberg NL, Levine BD, Thomas JD Relationship among diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness Am J Physiol Heart Circ Physiol, Apr 2006; 290: H1454 - H1459 micromanometer-tipped catheter dog aging; diastolic function; pulmonary capillary wedge pressure; isovolumic relaxation
Cannesson M, Jacques D, Pinsky MR, Gorcsan III J Effects of modulation of left ventricular contractile state and loading conditions on tissue Doppler myocardial performance index Am J Physiol Heart Circ Physiol, May 2006; 290: H1952 - H1959 MPC-500 dog contractility; echocardiography; ventricles
Kroeker CAG, Adeeb S, Shrive NG, Tyberg JV Compression induced by RV pressure overload decreases regional coronary blood flow in anesthetized dogs Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2432 - H2438 6-Fr micromanometer-tipped catheters dog diastole; mechanics; microspheres; right ventricle; left ventricle; finite element modeling; myocardial ischemia
Morita H, Khanal S, Rastogi S, Suzuki G, Imai M, Todor A, Sharov VG, Goldstein S, O'Neill TP, Sabbah HN Selective matrix metalloproteinase inhibition attenuates progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2522 - H2527 catheter-tip micromanometers dog hemodynamics; PG-530742; left ventricular ejection fraction
George I, Yi G-H, Schulman AR, Morrow BT, Cheng Y, Gu A, Zhang G, Oz MC, Burkhoff D, Wang J A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia Am J Physiol Heart Circ Physiol 291, Sep 2006: H1126-H1137, 2006 SPC-360S dog coronary; blood; nitric oxide inhibitor
Yada T, Shimokawa H, Hiramatsu O, Haruna Y, Morita Y, Kashihara N, Shinozaki Y, Mori H, Goto M, Ogasawara Y, Kajiya F Cardioprotective role of endogenous hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo Am J Physiol Heart Circ Physiol, Sep 2006; 291: H1138 - H1146 SPC-784A dog endothelium-derived relaxing factor; myocardial infarction; vascular endothelial function
Pacella JJ, Villanueva FS Effect of Coronary Stenosis on Adjacent Bed Flow Reserve: Assessment of Microvascular Mechanisms Using Myocardial Contrast Echocardiography Circulation, Oct 2006; 114: 1940 - 1947 high-fidelity micromanometer-tipped catheter dog flow reserve
Kroeker CAG, Adeeb S, Tyberg JV, Shrive NG A 2D FE model of the heart demonstrates the role of the pericardium in ventricular deformation Am J Physiol Heart Circ Physiol, Nov 2006; 291: H2229 - H2236 8-Fr micromanometer-tipped catheters dog ventricular function, right ventricular overload; finite element analysis
Cardinal R,Pagé P, Vermeulen M, Bouchard C, Ardell JL, Foreman RD, Armour JA Spinal cord stimulation suppresses bradycardias and atrial tachyarrhythmias induced by mediastinal nerve stimulation in dogs Am J Physiol Regulatory Integrative Comp Physiol, Nov 2006; 291: R1369 - R1375 Millar electronic pressure sensors dog intrinsic cardiac nervous system
Sun Y, Belenkie I, Wang J-J, Tyberg JV Assessment of right ventricular diastolic suction in dogs with the use of wave intensity analysis Am J Physiol Heart Circ Physiol, Dec 2006; 291: H3114 - H3121 SPC-471, SPR-524 dog diastole; hemodynamics; tricuspid valve; velocity; pressure
           
Kadem L, Dumesnil JG, Rieu R, Durand L-G, Garcia D, Pibarot P Impact of systemic hypertension on the assessment of aortic stenosis Heart 2005;91:354-361 multisensor Millar catheter pig aortic stenosis; Doppler echocardiography; haemodynamic function; hypertension; left ventricular function
Berg RA, Sorrell VL, Kern KB, Hilwig RW, Altbach MI, Hayes MM, Bates KA, Ewy GA Magnetic Resonance Imaging During Untreated Ventricular Fibrillation Reveals Prompt Right Ventricular Overdistention Without Left Ventricular Volume Loss Circulation, Mar 2005; 111: 1136 - 1140 MPC-500 pig cardiopulmonary resuscitation • heart arrest • hemodynamics • magnetic resonance imaging • ventricular fibrillation
Nielsen SL, Hansen SB, Nielsen KO, Nygaard H, Paulsen PK, Hasenkam JM Imbalanced chordal force distribution causes acute ischemic mitral regurgitation: Mechanistic insights from chordae tendineae force measurements in pigs J. Thorac. Cardiovasc. Surg., Mar 2005; 129: 525 - 531 SPC-350MR pig echocardiography
Deschamps AM, Apple KA, Leonardi AH, McLean JE, Yarbrough WM, Stroud RE, Clark LL, Sample JA, Spinale FG Myocardial Interstitial Matrix Metalloproteinase Activity Is Altered by Mechanical Changes in LV Load: Interaction With the Angiotensin Type 1 Receptor Circ. Res., May 2005; 96: 1110 - 1118 7.5 F pig matrix metalloproteinase • extracellular matrix • angiotensin II type I receptor
Yannopoulos D, Nadkarni VM, McKnite SH, Rao A, Kruger K, Metzger A, Benditt DG, Lurie KG Intrathoracic Pressure Regulator During Continuous-Chest-Compression Advanced Cardiac Resuscitation Improves Vital Organ Perfusion Pressures in a Porcine Model of Cardiac Arrest Circulation, Aug 2005; 112: 803 - 811 Mikro-Tip Transducer pig ITPR-CPR, STD-CPR
Sengupta PP, Khandheria BK, Korinek J, Wang J, Belohlavek M Biphasic tissue Doppler waveforms during isovolumic phases are associated with asynchronous deformation of subendocardial and subepicardial layers J Appl Physiol, Sep 2005; 99: 1104 - 1111 manometer-tipped catheters pig myocardial contraction; mechanics; echocardiography; tissue Doppler imaging; isovolumic contraction; isovolumic relaxation
Ovchinnikov V, Suzuki G, Canty Jr JM, Fallavollita JA Blunted functional responses to pre- and postjunctional sympathetic stimulation in hibernating myocardium Am J Physiol Heart Circ Physiol, Oct 2005; 289: H1719 - H1728 transducer-tipped catheter pig hibernation; sympathetic nerves; catecholamines; myocardial contraction
Iyer VS, Canty Jr JM Regional Desensitization of ß-Adrenergic Receptor Signaling in Swine With Chronic Hibernating Myocardium Circ. Res., Oct 2005; 97: 789 - 795 5F end-hole micromanometer pig ß-receptors • hibernating myocardium • chronic ischemic heart disease • adenylyl cyclase
Pandalai PK, Lyons JM, Duffy JY, McLean KM, Wagner CJ, Merrill WH, Pearl JM, Akhter SA Role of the ß-adrenergic receptor kinase in myocardial dysfunction after brain death J. Thorac. Cardiovasc. Surg., Oct 2005; 130: 1183 - 1189 Pressure transducer-tipped 2F or 3F catheters pig cyclic adenosine monophosphate
Yotti R, Bermejo J, Antoranz JC, Desco MM, Cortina C, Rojo-Álvarez JL, Allué C, Martín L, Moreno M, Serrano JA, Muñoz R, García-Fernández MA A Noninvasive Method for Assessing Impaired Diastolic Suction in Patients With Dilated Cardiomyopathy Circulation, Nov 2005; 112: 2921 - 2929 needle micromanometer, dual-micromanometer catheter (3-cm sensor spacing, Millar Instruments) pig cardiomyopathy • echocardiography • heart failure • imaging • diastole
Stanley WC, Morgan EE, Huang H, McElfresh TA, Sterk JP, Okere IC, Chandler MP, Cheng J, Dyck JRB, Lopaschuk GD Malonyl-CoA decarboxylase inhibition suppresses fatty acid oxidation and reduces lactate production during demand-induced ischemia Am J Physiol Heart Circ Physiol, Dec 2005; 289: H2304 - H2309 high-fidelity manometer-tipped catheter pig carnitine palmitoyltransferase-I; glucose; heart; lactate; myocardium
Rondelet B, Kerbaul F, Van Beneden R, Hubloue I, Huez S, Fesler P, Remmelink M, Brimioulle S, Salmon I, Naeije R Prevention of pulmonary vascular remodeling and of decreased BMPR-2 expression by losartan therapy in shunt-induced pulmonary hypertension Am J Physiol Heart Circ Physiol, Dec 2005; 289: H2319 - H2324 SPC-350 pig left-to-right shunt; angiotensin II; endothelin-1; angiopoietin; bone morphogenetic protein receptor-2
Santana DB, Barra JG, Grignola JC, Ginés FF, Armentano RL Pulmonary artery smooth muscle activation attenuates arterial dysfunction during acute pulmonary hypertension J Appl Physiol 98: 605-613, 2005. SPC-370, 7F sheep buffering function; arterial wall viscoelasticity; characteristic impedance
Santana DB, Barra JG, Grignola JC, Ginés FF, Armentano RL Pulmonary artery smooth muscle activation attenuates arterial dysfunction during acute pulmonary hypertension J Appl Physiol 98: 605-613, 2005. SPC-370, 7F sheep buffering function; arterial wall viscoelasticity; characteristic impedance
Harrington KB, Rodriguez F, Cheng A, Langer F, Ashikaga H, Daughters GT, Criscione JC, Ingels NB, Miller DC Direct measurement of transmural laminar architecture in the anterolateral wall of the ovine left ventricle: new implications for wall thickening mechanics Am J Physiol Heart Circ Physiol, Mar 2005; 288: H1324 - H1330 SPC-500 sheep cardiac microstructure; sheets
Enomoto Y, Gorman III JH, Moainie SL, Guy TS, Jackson BM, Parish LM, Plappert T, Zeeshan A, St. John-Sutton MG, Gorman RC Surgical treatment of ischemic mitral regurgitation might not influence ventricular remodeling J. Thorac. Cardiovasc. Surg., Mar 2005; 129: 504 - 511 SPC-350 sheep post-infarction remodeling
Cheng A, Langer F,Rodriguez F, Criscione JC, Daughters GT, Miller DC, Ingels Jr NB Transmural cardiac strains in the lateral wall of the ovine left ventricle Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1546 - H1556 MPC-500 sheep wall thickening; left ventricle myocardium; systolic function
Hashimoto I, Li X-K, Hejmadi Bhat AH, Jones M, Sahn DJ Quantitative assessment of regional peak myocardial acceleration during isovolumic contraction and relaxation times by tissue Doppler imaging Heart, Jun 2005; 91: 811 - 816 SPC-350 sheep contractility; echocardiography; relaxation; ventricle
Langer F, Rodriguez F, Ortiz S, Cheng A, Nguyen TC, Zasio MK, Liang D, Daughters GT, Ingels NB, Miller DC Subvalvular Repair: The Key to Repairing Ischemic Mitral Regurgitation? Circulation, Aug 2005; 112: I-383 - I-389 SPC-500 sheep ischemic mitral regurgitation • mitral valve • mitral valve repair
Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Fata B, Hsu EW, Saloner D, Guccione JM MRI-based finite-element analysis of left ventricular aneurysm Am J Physiol Heart Circ Physiol, Aug 2005; 289: H692 - H700 SPC-320 sheep tagged magnetic resonance imaging; computational modeling; diffusion tensor magnetic resonance imaging; ventricular remodeling; congestive heart failure
Langeland S, D’hooge J, Wouters PF, Leather HA, Claus P, Bijnens B, Sutherland GR Experimental Validation of a New Ultrasound Method for the Simultaneous Assessment of Radial and Longitudinal Myocardial Deformation Independent of Insonation Angle Circulation, Oct 2005; 112: 2157 - 2162 Millar catheter sheep echocardiography • strain • angle dependency
Martinez RR, Setty S, Zong P, Tune JD, Downey HF Nitric oxide contributes to right coronary vasodilation during systemic hypoxia Am J Physiol Heart Circ Physiol, Mar 2005; 288: H1139 - H1146 high-fidelity 3-Fr micro-tip catheter pressure transducer dog right ventricular function; right ventricular oxygen balance; myocardial oxygen consumption
Xu J, Kussmaul W, Kurnik PB, Al-Ahdav M, Pelleg A Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. V. Role of purinergic receptors Am J Physiol Regulatory Integrative Comp Physiol, Mar 2005; 288: R651 - R655 electronic pressure transducer-tipped catheter dog P2X; 2',3'-O-(2,4,6-trinitrophenyl)-ATP; diinosine pentaphosphate; vasovagal syncope
Lyseggen E, Rabben SI, Skulstad H, Urheim S, Risoe C, Smiseth OA Myocardial Acceleration During Isovolumic Contraction: Relationship to Contractility Circulation, Mar 2005; 111: 1362 - 1369 MPC-500 dog echocardiography • ischemia • contractility • myocardial contraction • acceleration
Corvera JS, Kin H, Dobson GP, Kerendi F, Halkos ME, Katzmark S, Payne CS, Zhao Z-Q, Guyton RA, Vinten-Johansen J Polarized arrest with warm or cold adenosine/lidocaine blood cardioplegia is equivalent to hypothermic potassium blood cardioplegia J. Thorac. Cardiovasc. Surg., Mar 2005; 129: 599 - 606 MPC-500 dog myocardial protection, cardioplegia
Caswell JE, Strange MB, Rimmer III DM, Gibson MF, Cole P, Lefer DJ A novel hemoglobin-based blood substitute protects against myocardial reperfusion injury Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1796 - H1801 MPC-500, MPC-350 dog infarction; contractility; neutrophils; ischemia
Toyota E, Ogasawara Y, Hiramatsu O, Tachibana H, Kajiya F, Yamamori S, Chilian WM Dynamics of flow velocities in endocardial and epicardial coronary arterioles Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1598 - H1603 SPC-784A dog microcirculation; circulation; rheology; ischemia
Wang Z, Jalali F, Sun Y-H, Wang J-J, Parker KH, Tyberg JV Assessment of left ventricular diastolic suction in dogs using wave-intensity analysis Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1641 - H1651 catheter-tip manometers dog diastole; hemodynamics; mitral valve; ventricles
Urheim S, Rabben SI, Skulstad H, Lyseggen E, Ihlen H, Smiseth OA Regional myocardial work by strain Doppler echocardiography and LV pressure: a new method for quantifying myocardial function Am J Physiol Heart Circ Physiol, May 2005; 288: H2375 - H2380 MPC-500 dog sonomicrometry; pressure-strain loop
Helm RH, Leclercq C, Faris OP, Ozturk C, McVeigh E, Lardo AC, Kass DA Cardiac Dyssynchrony Analysis Using Circumferential Versus Longitudinal Strain: Implications for Assessing Cardiac Resynchronization Circulation, May 2005; 111: 2760 - 2767 1.4F Millar microtip catheter dog resynchronization therapy • heart failure • bundle-branch block • pacing
Wang, Abraham TP, Korinek J, Urheim S, McMahon EM, Belohlavek M Delayed Onset of Subendocardial Diastolic Thinning at Rest Identifies Hypoperfused Myocardium Circulation, Jun 2005; 111: 2943 - 2950 6F micromanometer catheter dog myocardial relaxation • ischemia • regional blood flow • echocardiography • diastole
Uemura K, Kawada T, Kamiya A, Aiba T, Hidaka I, Sunagawa K, Sugimachi M Prediction of circulatory equilibrium in response to changes in stressed blood volume Am J Physiol Heart Circ Physiol, Jul 2005; 289: H301 - H307 SPC-751 dog β-adrenoceptors; congestive heart failure; G protein-coupled receptor kinase; renin-angiotensin system blockade
Mitchell JR, Whitelaw WA, Sas R, Smith ER, Tyberg JV, Belenkie I RV filling modulates LV function by direct ventricular interaction during mechanical ventilation Am J Physiol Heart Circ Physiol, Aug 2005; 289: H549 - H557 SPC-484A dog right ventricle; left ventricle
Gaynor SL, Maniar HS, Bloch JB, Steendijk P, Moon MR Right Atrial and Ventricular Adaptation to Chronic Right Ventricular Pressure Overload Circulation, Aug 2005; 112: I-212 - I-218 MPC-500, SPR-843 dog atrium • hypertension, pulmonary • pulmonary heart disease
Kochupura PV, Azeloglu EU, Kelly DJ, Doronin SV, Badylak SF, Krukenkamp IB, Cohen IS, Gaudette GR Tissue-Engineered Myocardial Patch Derived From Extracellular Matrix Provides Regional Mechanical Function Circulation, Aug 2005; 112: I-144 - I-149 pressure transducer dog heart failure • surgery • mechanics • remodeling • myocytes
Hennan JK, Elokdah H, Leal M, Ji A, Friedrichs GS, Morgan GA, Swillo RE, Antrilli TM, Hreha A, Crandall DL  Evaluation of PAI-039 [{1-Benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic Acid], a Novel Plasminogen Activator Inhibitor-1 Inhibitor, in a Canine Model of Coronary Artery Thrombosis  JPET 314:710-716, 2005 Mikro-tip catheter dog electrolytic injury