| AUTHORS |
TITLE |
JOURNAL |
MILLAR EQPT. |
SUBJECT |
application |
---------------------------------------------Published in 2010--------------------------------------------
|
| Barry WH, Zhang XQ, Halkos ME, Vinten-Johansen J, Saegusa N, Spitzer KW, Matsuoka N, Sheets M, Rao NV, Kennedy TP |
Nonanticoagulant heparin reduces myocyte Na+ and Ca2+ loading during simulated ischemia and decreases reperfusion injury |
Am J Physiol Heart Circ Physiol, Jan 2010; 298: H102 - H111 |
solid-state transducer-tipped catheter |
pig |
metabolic inhibition; sodium-calcium exchange; late sodium current; ranolazine; myocardial reperfusion injury; nonanticoagulant heparin |
| Espinoza A, Halvorsen PS, Hoff L, Skulstad H, Fosse E, Ihlen H, Edvardsen T |
Detecting myocardial ischaemia using miniature ultrasonic transducers — a feasibility study in a porcine model |
Eur. J. Cardiothorac. Surg., January 2010; 37: 119 - 126 |
MPC-500, TC-510 |
pig |
Myocardial ischaemia • Cardiac surgical procedures • Echocardiography |
| Voss B, Krane M, Jung C, Brockmann G, Braun S, Günther T, Lange R, Bauernschmitt R |
Cardiopulmonary bypass with physiological flow and pressure curves: pulse is unnecessary! |
Eur. J. Cardiothorac. Surg., January 2010; 37: 223 - 232 |
SPC-350 |
pig |
Extracorporeal circulation • Pulsatile flow • Non-pulsatile flow • Microcirculation • Energy-equivalent pressure • Capillary leak |
| te Lintel Hekkert M, Dubé GP, Regar E, de Boer M, Vranckx P, van der Giessen WJ, Serruys PW, Duncker DJ |
Preoxygenated hemoglobin-based oxygen carrier HBOC-201 annihilates myocardial ischemia during brief coronary artery occlusion in pigs |
Am J Physiol Heart Circ Physiol, Mar 2010; 298: H1103 - H1113. |
micromanometer-tipped catheter |
pig |
coronary blood flow; intracoronary infusion; left ventricular function; myocardial metabolism |
| Lee LS, Ghanta RK, Mokashi SA, Coelho-Filho O, Kwong RY, Bolman III RM, Chen FY |
Ventricular restraint therapy for heart failure: The right ventricle is different from the left ventricle |
J. Thorac. Cardiovasc. Surg., April 2010; 139: 1012 - 1018 |
High-fidelity micromanometers |
sheep |
|
| Dubois C, Liu X, Claus P, Marsboom G, Pokreisz P, Vandenwijngaert S, Dépelteau H, Streb W, Chaothawee L, Maes F, Gheysens O, Debeyser Z, Gillijns H, Pellens M, Vandendriessche T, Chuah M, Collen D, Verbeken E, Belmans A, Van de Werf F, Bogaert J, Janssens S |
Differential Effects of Progentior Cell Populations on Left Ventricular Remodeling and Myocardial Neovascularization after Myocardial Infarction |
JACC vol. 55, No. 20, 2010: May 18, 2010:2232-43 |
7-F Millar catheter |
pig |
cell therapy, endothelial progenitor cells, left ventricular remodeling, mesenchymal stem cells, myocardial infarction |
| Seo J-S, Kim D-H, Kim W-J, Song J-M, Kang D-H, Song J-K |
Peak systolic velocity of mitral annular longitudinal movement measured by pulsed tissue Doppler imaging as an index of global left ventricular contractility |
Am J Physiol Heart Circ Physiol, May 2010; 298: H1608 - H1615 |
dual high-fidelity pressure sensor |
dog |
contractility; echocardiography; longitudinal movement; ventricular rotation |
| Wenk JF, Zhang Z, Cheng G, Malhotra D, Acevedo-Bolton G, Burger M, Suzuki T, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB |
First Finite Element Model of the Left Ventricle With Mitral Valve: Insights Into Ischemic Mitral Regurgitation |
Ann. Thorac. Surg., May 2010; 89: 1546 - 1553 |
SPC-350 |
sheep |
|
---------------------------------------------Published in 2009---------------------------------------------
|
| Zierer A, Melby SJ, Voeller RK, Moon MR |
Interatrial Shunt for Chronic Pulmonary Hypertension: Differential Impact of Low-Flow versus High-Flow Shunting |
Am J Physiol HearMPC-500t Circ Physiol, Jan 2009; doi:10.1152/ajpheart.00496.2008 |
MPC-500 |
dog |
ideal shunt fraction |
| Suzuki G, Iyer V, Cimato T, Canty Jr JM |
Pravastatin Improves Function in Hibernating Myocardium by Mobilizing CD133+ and cKit+ Bone Marrow Progenitor Cells and Promoting Myocytes to Reenter the Growth Phase of the Cardiac Cell Cycle |
Circ. Res., Jan 2009; 104: 255 - 264 |
Millar catheter |
pig |
statins • hibernating myocardium • cardiac repair • bone marrow progenitor cells |
| Schmitto JD, Doerge H, Post H, Coulibaly M, Sellin C, Popov AF, Sossalla S, Schoendube FA |
Progressive right ventricular failure is not explained by myocardial ischemia in a pig model of right ventricular pressure overload |
Eur. J. Cardiothorac. Surg., February 2009; 35: 229 - 234 |
5 F |
pig |
Right ventricular function • Pressure overload • Ischemia • Pulmonary embolism |
| Xu D, Olivier NB, Mukkamala R |
Continuous cardiac output and left atrial pressure monitoring by long time interval analysis of the pulmonary artery pressure waveform: proof of concept in dogs |
J Appl Physiol, Feb 2009; 106: 651 - 661 |
micromanometer-tipped catheter |
dog |
mathematical modeling; pulmonary artery catheter; pulmonary capillary wedge pressure; pulse contour analysis; thermodilution |
| Timmers L, Henriques JPS, de Kleijn DPV, J. DeVries H, Kemperman H, Steendijk P, Verlaan CWJ, Kerver M, Piek JJ, Doevendans PA, Pasterkamp G, Hoefer IE |
Exenatide Reduces Infarct Size and Improves Cardiac Function in a Porcine Model of Ischemia and Reperfusion Injury |
J. Am. Coll. Cardiol., February 10, 2009; 53: 501 - 510 |
pressure-tipped Millar catheter |
pig |
TUNEL, pAkt |
| Walcott G, Melnick S, Killingsworth C, Ideker R |
Burst Stimulation Improves Hemodynamics During Resuscitation After Prolonged Ventricular Fibrillation |
Circ Arrhythm Electrophysiol, Feb 2009; 2: 57 - 62 |
high fidelity pressure catheter |
pig |
ventricular fibrillation • resuscitation • electric stimulation |
| Chakir K, Daya SK, Aiba T, Tunin RS, Dimaano VL, Abraham TP, Jacques K, Lai EW, Pacak K, Zhu W-Z, Xiao R-p, Tomaselli GF, Kass DA |
Mechanisms of Enhanced β-Adrenergic Reserve From Cardiac Resynchronization Therapy |
Circulation, Mar 2009; 119: 1231 - 1240 |
micromanometer |
dog |
heart failure treatment, chamber systolic function |
| Zierer A, Melby SJ, Voeller RK, Moon MR |
Interatrial shunt for chronic pulmonary hypertension: differential impact of low-flow vs. high-flow shunting |
Am J Physiol Heart Circ Physiol, Mar 2009; 296: H639 - H644 |
MPC-500 |
dog |
right heart failure; atrial septostomy right ventricular overload |
| Lyseggen E, Vartdal T, Remme EW, Helle-Valle T, Pettersen E, Opdahl A, Edvardsen T, Smiseth OA |
A novel echocardiographic marker of end systole in the ischemic left ventricle: "tug of war" sign |
Am J Physiol Heart Circ Physiol, Mar 2009; 296: H645 - H654 |
MPC-500 |
dog |
echocardiography; infarction; reperfusion; ventricular function; tissue Doppler imaging |
| Khoury DS, Naware M, Siou J, Blomqvist A, Mathuria NS, Wang J, Shih H-T, Nagueh SF, Panescu D |
Ambulatory Monitoring of Congestive Heart Failure by Multiple Bioelectric Impedance Vectors |
J. Am. Coll. Cardiol., March 24, 2009; 53: 1075 - 1081 |
SPC-350 |
dog |
cardiac resynchronization therapy • hemodynamic monitoring • pulmonary edema |
| Indik JH, Hilwig RW, Zuercher M, Kern KB, Berg MD, Berg RA |
Preshock Cardiopulmonary Resuscitation Worsens Outcome From Circulatory Phase Ventricular Fibrillation With Acute Coronary Artery Obstruction in Swine |
Circ Arrhythmia Electrophysiol, Apr 2009; 2: 179 - 184 |
MCP-500 |
pig |
cardiopulmonary resuscitation • myocardial infarction • heart arrest • ventricular fibrillation defibrillation |
| Sodha NR, Clements RT, Feng J, Liu Y, Bianchi C, Horvath EM, Szabo C, Sellke FW |
The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia–reperfusion injury |
Eur. J. Cardiothorac. Surg., May 2008; 33: 906 - 913. |
catheter-tipped manometer |
pig |
Ischemia • Reperfusion • Apoptosis • Cardiac • Sulfide • Protection |
| Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Hsu EW, Saloner DA, Guccione JM |
Magnetic resonance imaging-based finite element stress analysis after linear repair of left ventricular aneurysm |
J. Thorac. Cardiovasc. Surg., May 2008; 135: 1094 - 1102 |
SPC-320 |
sheep |
|
| Hisagi M, Suematsu Y, Masuzawa A, Ono M, Motomura N, Takamoto S |
Image-guided surgical repair of ventricular septal rupture using self-expanding device |
Interactive CardioVascular and Thoracic Surgery, Jun 2009; 8: 602 - 605 |
5 Fr micromanometer-tipped catheter |
pig |
Minimally invasive surgery; Device; Echocardiography; Myocardial infarction |
| Sheikh AM, Barrett C, Villamizar N, Alzate O, Valente AM, Herlong JR, Craig D, Lodge A, Lawson J, Milano C, Jaggers J |
Right ventricular hypertrophy with early dysfunction: A proteomics study in a neonatal model |
J. Thorac. Cardiovasc. Surg., May 2009; 137: 1146 - 1153 |
micromanometer catheter |
pig |
|
| Osipov RM, Robich MP, Feng J, Clements RT, Liu Y, Glazer HP, Wagstaff J, Bianchi C, Sellke FW |
Effect of thrombin fragment (TP508) on myocardial ischemia-reperfusion injury in hypercholesterolemic pigs |
J Appl Physiol, Jun 2009; 106: 1993 - 2001 |
catheter-tipped manometer |
pig |
myocardial function; microvascular reactivity; apoptosis; cell survival signaling |
| Sridhar A, Nishijima Y, Terentyev D, Khan M, Terentyeva R, Hamlin RL, Nakayama T, Gyorke S, Cardounel AJ, Carnes CA |
Chronic heart failure and the substrate for atrial fibrillation |
Cardiovasc Res, Advance Access published on July 17, 2009; doi: doi:10.1093/cvr/cvp216 |
SPC-350 |
dog |
Heart failure; Arrhythmia (mechanisms); Remodelling; K-channel |
| Gross GJ, Gauthier KM, Moore J, Campbell WB, Falck JR, Nithipatikom K |
Evidence for role of epoxyeicosatrienoic acids in mediating ischemic preconditioning and postconditioning in dog |
Am J Physiol Heart Circ Physiol, Jul 2009; 297: H47 - H52. |
double-tipped Millar (model 770) catheter |
dog |
cytochrome P-450 epoxygenases; epoxyeicosatrienoic acid antagonists; ischemia-reperfusion |
| Osipov RM, Robich MP, Feng J, Clements RT, Liu Y, Glazer HP, Wagstaff J, Bianchi C, Sellke FW |
Effect of thrombin fragment (TP508) on myocardial ischemia-reperfusion injury in hypercholesterolemic pigs |
Am J Physiol Heart Circ Physiol, Jul 2009; 297: H47 - H52. |
catheter-tipped manometer |
pig |
myocardial function; microvascular reactivity; apoptosis; cell survival signaling |
| Smolich JJ, Mynard JP, Penny DJ |
Dynamic characterization and hemodynamic effects of pulmonary waves in fetal lambs using cardiac extrasystoles and beat-by-beat wave intensity analysis |
Am J Physiol Regulatory Integrative Comp Physiol, Aug 2009; 297: R428 - R436 |
TCB-500, 2.5 F micromanometer catheter |
sheep |
fetal pulmonary blood flow; fetal pulmonary blood pressure; post-extrasystolic potentiation |
| Ardell JL, Cardinal R, Vermeulen M, Armour JA |
Dorsal spinal cord stimulation obtunds the capacity of intrathoracic extracardiac neurons to transduce myocardial ischemia |
Am J Physiol Regulatory Integrative Comp Physiol, Aug 2009; 297: R470 - R477. |
Millar catheter |
dog |
cardiac pacing; ventricular ischemia; middle cervical ganglion neuron; cardiac nervous system; neurocardiology |
| Bothe W, Nguyen TC, Roberts ME,Timek TA, Itoh A, Ingels Jr NB, Miller DC |
Presystolic mitral annular septal–lateral shortening is independent from left atrial and left ventricular contraction during acute volume depletion |
Eur. J. Cardiothorac. Surg., August 2009; 36: 236 - 243 |
micromanometer catheter |
sheep |
Mitral annular dynamics • Acute volume depletion • Radiopaque markers • Ovine model |
| Badiwala MV, Ramzy D, Tumiati LC, Tepperman ED, Sheshgiri R, Prodger JL, Feindel CM, Rao V |
Donor Pretreatment With Hypertonic Saline Attenuates Primary Allograft Dysfunction: A Pilot Study in a Porcine Model |
Circulation, Sep 2009; 120: S206 - S214 |
Millar micromanometer and conductance catheters |
pig |
endothelium • ischemia • transplantation • reperfusion |
| Osipov RM, Bianchi C, Feng J, Clements RT, Liu Y, Robich MP, Glazer HP, Sodha NR, Sellke FW |
Effect of Hypercholesterolemia on Myocardial Necrosis and Apoptosis in the Setting of Ischemia-Reperfusion |
Circulation, Sep 2009; 120: S22 - S30 |
catheter-tipped manometer |
pig |
apoptosis • hypercholesterolemia • ischemia • myocardial infarction • risk factors |
| Johnston PV, Sasano T, Mills K, Evers R, Lee S-T, Smith RR, Lardo AC, Lai S, Steenbergen C, Gerstenblith G, Lange R, Marbán E |
Engraftment, Differentiation, and Functional Benefits of Autologous Cardiosphere-Derived Cells in Porcine Ischemic Cardiomyopathy |
Circulation, Sep 2009; 120: 1075 - 1083 |
Circulation, Sep 2009; 120: 1075 - 1083 |
pig |
|
| Smolich JJ, Mynard JP, Penny DJ |
Ductus arteriosus wave intensity analysis in fetal lambs: midsystolic ductal flow augmentation is due to antegrade pulmonary arterial wave transmission |
Am J Physiol Regulatory Integrative Comp Physiol, Oct 2009; 297: R1171 - R1179 |
TCB-500 |
Sheep |
ductus arteriosus blood flow; ductus arteriosus blood pressure; fetal central hemodynamics |
| Bebarta VS, Pitotti RL, Dixon P, Valtier S, Little CM |
Abstract 2505: Hydroxocobalamin and Epinephrine Improve Survival in a Swine Model of Cyanide-Induced Cardiac Arrest: A Randomized Trial |
Circulation, Nov 2009; 120: S652 |
Millar catheters |
pig |
resuscitation |
| Shapiro S, Kawase Y, Ladage D, Martinez GG, Sanz J, Garcia MJ, Chaudhry HW, Hajjar RJ |
Abstract 3174: Administration of Cyclin A2 by Gene Transfer Improves Cardiac Function in a Porcine Model of Myocardial Infarction |
Circulation, Nov 2009; 120: S754 |
Millar catheter |
pig |
cardiac regeneration, cellular therapy |
| Swamy G, Xu D, Olivier NB, Mukkamala R |
An adaptive transfer function for deriving the aortic pressure waveform from a peripheral artery pressure waveform |
Am J Physiol Heart Circ Physiol, Nov 2009; 297: H1956 - H1963 |
micromanometer-tipped catheter |
dog |
arterial tree; blood pressure; generalized transfer function; model; wave reflection |
| Quinn TA, Cabreriza SE, Richmond ME, Weinberg AD, Holmes JW, . Spotnitz HM |
Simultaneous variation of ventricular pacing site and timing with biventricular pacing in acute ventricular failure improves function by interventricular assist |
Am J Physiol Heart Circ Physiol, Dec 2009; 297: H2220 - H2226 |
5F solid-state pressure transducer catheter |
pig |
heart failure; cardiac pacing; hemodynamics; cardiac mechanics; cardiac surgery |
---------------------------------------------Published in 2008---------------------------------------------
|
| Zhou L, Huang H, Yuan CL, Keung W, Lopaschuk GD, Stanley WC |
Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation |
Am J Physiol Heart Circ Physiol, Feb 2008; 294: H954 - H960 |
high-fidelity pressure transducer |
pig |
acetyl-CoA carboxylase; AMP-activated protein kinase; exercise; fatty acids; heart; mitochondria |
| Kawase Y, Ly HQ, Prunier F, Lebeche D, YShi Y, Jin H, Hadri L, Yoneyama R, Hoshino K, Takewa Y, Sakata S, Peluso R, Zsebo K, Gwathmey JK, Tardif J-C, Tanguay J-F, Hajjar RJ |
Reversal of Cardiac Dysfunction After Long-Term Expression of SERCA2a by Gene Transfer in a Pre-Clinical Model of Heart Failure |
J. Am. Coll. Cardiol., March 18, 2008; 51: 1112 - 1119 |
6-F Millar MIKRO-TIP catheter |
pig |
mitral regurgitation |
| Pandalai PK, McLean KM, Bulcao CF, Duffy JY, D'Souza KM, Merrill WH, Pearl JM, Akhter SA |
Acute β-blockade prevents myocardial β-adrenergic receptor desensitization and preserves early ventricular function after brain death |
J. Thorac. Cardiovasc. Surg., April 2008; 135: 792 - 798 |
Pressure transducer-tipped 2F or 3F catheters |
pig |
adenylate cyclase; heart failure; preload recruitable stroke work |
| Penny DJ, Mynard JP, Smolich JJ |
Aortic wave intensity analysis of ventricular-vascular interaction during incremental dobutamine infusion in adult sheep |
Am J Physiol Heart Circ Physiol, Jan 2008; 294: H481 - H489 |
MPC-500, TCB-500 |
sheep |
hemodynamics; wave propagation; arterial circulation; blood velocity |
| Beeri R, Yosefy C, Guerrero JL, Nesta F, Abedat S, Chaput M, del Monte F, Handschumacher MD, Stroud R, Sullivan S, Pugatsch T, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA |
Mitral Regurgitation Augments Post-Myocardial Infarction Remodeling: Failure of Hypertrophic Compensation |
J. Am. Coll. Cardiol., January 29, 2008; 51: 476 - 486 |
high-fidelity micromanometer-tipped catheter |
sheep |
dilated heart failure |
| Notomi Y, Popovic ZB, Yamada H, Wallick DW, Martin MG, Oryszak SJ, Shiota T, Greenberg NL, Thomas JD |
Ventricular untwisting: a temporal link between left ventricular relaxation and suction |
Am J Physiol Heart Circ Physiol, Jan 2008; 294: H505 - H513 |
triple-sensor Millar catheter (40 mm, distal to middle; and 20 mm, middle to proximal; Millar Instruments) |
dog |
diastole; relaxation; suction; torsion |
| Hong T-T, Huang J, Barrett TD, Lucchesi BR |
Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis |
Am J Physiol Heart Circ Physiol, Jan 2008; 294: H145 - H155 |
Millar blood pressure catheter transducer |
dog |
inflammation; vascular reactivity |
| Banfor PN, Preusser LC, Campbell TJ, Marsh KC, Polakowski JS, Reinhart GA, Cox BF, Fryer RM |
Comparative effects of levosimendan, OR-1896, OR-1855, dobutamine, and milrinone on vascular resistance, indexes of cardiac function, and O2 consumption in dogs |
Am J Physiol Heart Circ Physiol, Jan 2008; 294: H238 - H248 |
SPC-770, 7F |
dog |
cardiac contractility, vasdilation |
| Rao L, Ling Y, He R, Gilbert AL, Frangogiannis NG, Wang J, Nagueh SF, Khoury DS |
Integrated multimodal-catheter imaging unveils principal relationships among ventricular electrical activity, anatomy, and function |
Am J Physiol Heart Circ Physiol, Feb 2008; 294: H1002 - H1009 |
SPC-350 |
dog |
electrophysiology; myocardial infarction; noncontact mapping |
| Pirat B, Khoury DS, Hartley CJ, Tiller L, Rao L, Schulz DG, Nagueh SF, Zoghbi WA |
A Novel Feature-Tracking Echocardiographic Method for the Quantitation of Regional Myocardial Function: Validation in an Animal Model of Ischemia-Reperfusion |
J. Am. Coll. Cardiol., February 12, 2008; 51: 651 - 659 |
SPC-350 |
dog |
velocity vector imaging |
| Wang J-J, Shrive NG, Parker KH, Tyberg JV |
Effects of vasoconstriction and SPR-838 vasodilatation on LV and segmental circulatory energetics |
Am J Physiol Heart Circ Physiol, Mar 2008; 294: H1216 - H1225 |
SPR-838 |
|
left ventricle circulatory coupling; systemic vascular resistance; arterial and venous reservoirs |
| Xiao Y-F, Sigg DC, Ujhelyi MR, Wilhelm JJ, Richardson ES, Iaizzo PA |
Pericardial delivery of omega-3 fatty acid: a novel approach to reducing myocardial infarct sizes and arrhythmias |
Am J Physiol Heart Circ Physiol, May 2008; 294: H2212 - H2218 |
MPC-500 |
pig |
ischemia-reperfusion; pericardium; arrhythmia; myocardial infarction; n-3 polyunsaturated fatty acid |
| Smolich JJ, Mynard JP, Penny DJ |
Simultaneous pulmonary trunk and pulmonary arterial wave intensity analysis in fetal lambs: evidence for cyclical, midsystolic pulmonary vasoconstriction |
Am J Physiol Regulatory Integrative Comp Physiol, May 2008; 294: R1554 - R1562 |
TCB-500 |
sheep |
fetal pulmonary vascular interaction; fetal pulmonary blood flow; fetal pulmonary blood pressure |
| Sodha NR, Clements RT, Feng J, Liu Y, Bianchi C, Horvath EM, Szabo C, Sellke FW |
The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia–reperfusion injury |
Eur. J. Cardiothorac. Surg., May 2008; 33: 906 - 913 |
catheter-tipped manometer |
pig |
Ischemia • Reperfusion • Apoptosis • Cardiac • Sulfide • Protection |
| Desai KV, Laine GA, Stewart RH, Cox Jr CS, Quick CM, Allen SJ, Fischer UM |
Mechanics of the left ventricular myocardial interstitium: effects of acute and chronic myocardial edema |
Am J Physiol Heart Circ Physiol, Jun 2008; 294: H2428 - H2434 |
solid-state pressure transducers |
dog |
left ventricular chamber compliance; compliance resetting; edemagenic gain |
| Gross GJ, Gauthier KM, Moore J, Falck JR, Hammock BD, Campbell WB, Nithipatikom K |
Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart |
Am J Physiol Heart Circ Physiol, Jun 2008; 294: H2838 - H2844 |
SPC-770, double-tipped Millar |
dog |
cytochrome P-450 epoxygenase; epoxyeicosatrienoic acids; soluble epoxide hydrolase; ATP-sensitive potassium channel opener |
| Remme EW, Lyseggen E, Helle-Valle T, Opdahl A, Pettersen E, Vartdal T, Ragnarsson A, Ljosland M, Ihlen H, Edvardsen T, Smiseth OA |
Mechanisms of Preejection and Postejection Velocity Spikes in Left Ventricular Myocardium: Interaction Between Wall Deformation and Valve Events |
Circulation, Jul 2008; 118: 373 - 380 |
MPC-500 |
dog, human |
myocardium |
| Prunier F, Kawase Y, Gianni D, Scapin C, Danik SB, Ellinor PT, Hajjar RJ, del Monte F |
Prevention of Ventricular Arrhythmias With Sarcoplasmic Reticulum Ca2+ ATPase Pump Overexpression in a Porcine Model of Ischemia Reperfusion |
Circulation, Aug 2008; 118: 614 - 624 |
Millar pigtail catheter |
pig |
ventricular arrhythmias |
| Cheng A, Nguyen TC, Malinowski M, Daughters GT, Miller DC, Ingels Jr NB |
Heterogeneity of Left Ventricular Wall Thickening Mechanisms |
Circulation, Aug 2008; 118: 713 - 721 |
MPC-500 |
sheep |
transmural LV intercellular architecture |
| Hung J, Solis J, Guerrero JL, Braithwaite GJC, Muratoglu OK, Chaput M, Fernandez-Friera L, Handschumacher MD, Wedeen VJ, Houser S, Vlahakes GJ, Levine RA |
A Novel Approach for Reducing Ischemic Mitral Regurgitation by Injection of a Polymer to Reverse Remodel and Reposition Displaced Papillary Muscles |
Circulation, Sep 2008; 118: S263 - S269 |
micromanometer-tipped Millar catheter |
sheep |
coronary artery disease • left ventricular remodeling • mitral regurgitation |
| Carlhäll CJ, Nguyen TC, Itoh A, Ennis DB, Bothe W, Liang D, Ingels NB, Miller DC |
Alterations in Transmural Myocardial Strain: An Early Marker of Left Ventricular Dysfunction in Mitral Regurgitation? |
Circulation, Sep 2008; 118: S256 - S262 |
micromanometer catheter |
sheep |
LV dysfunction • mitral regurgitation • timing of surgery • transmural strain |
| Jensen MO, Jensen H, Smerup M, Levine RA, Yoganathan AP, Nygaard H, Hasenkam M, Nielsen SL |
Saddle-Shaped Mitral Valve Annuloplasty Rings Experience Lower Forces Compared With Flat Rings |
Circulation, Sep 2008; 118: S250 - S255 |
SPC-350MR |
pig |
mitral valve • mitral annuloplasty rings • heart valve diseases |
| Krishnamurthy G, Ennis DB, Itoh A, Bothe W, Swanson JC, Karlsson M, Kuhl E, Miller DC, Ingels Jr NB. |
Material properties of the ovine mitral valve anterior leaflet in vivo from inverse finite element analysis |
Am J Physiol Heart Circ Physiol, Sep 2008; 295: H1141 - H1149. |
MPC-500 |
sheep |
mitral valve material properties; inverse finite-element analysis; ovine model; radiopaque markers |
| Zhou L, Huang H, McElfresh TA, Prosdocimo DA, Stanley WC |
Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia |
Am J Physiol Heart Circ Physiol, Sep 2008; 295: H939 - H945. |
7-Fr high-fidelity transducer catheter |
pig |
angina; fatty acids; glucose; insulin |
| Banz Y, Rieben R, Zobrist C, Meier P, Shaw S, Lanz J, Carrel T, Berdat P |
Addition of dextran sulfate to blood cardioplegia attenuates reperfusion injury in a porcine model of cardiopulmonary bypass |
Eur. J. Cardiothorac. Surg., September 2008; 34: 653 - 660 |
high-fidelity pressure-sensitive tip transducer |
pig |
Ischemia • Reperfusion • Complement inhibition • Cytoprotection • Endothelium |
| Nguyen TC, Itoh A, Carlhäll CJ, Bothe W, Timek TA, Ennis DB, Oakes RA, Liang D, Daughters GT, Ingels Jr NB, Miller DC |
The effect of pure mitral regurgitation on mitral annular geometry and three-dimensional saddle shape |
J. Thorac. Cardiovasc. Surg., September 2008; 136: 557 - 565 |
micromanometer catheter |
sheep |
annuloplasty rings |
| Hu X, Mangat I, Leong-Poi H, Ramadeen A, Dorian P |
Abstract P18: Automated High Frequency Ventilation During Experimental CPR: A New Approach to Resuscitation |
Circulation, Oct 2008; 118: S_1448 - S_1449 |
solid state Millar transducers |
pig |
manual over-ventilation |
| Duffy JY, Baker RS, Basu M, Reed C, Heeb EA, Eghtesady P |
Abstract 5399: Myocardial Contractile Dysfunction is Associated with Fetal Cardiac Bypass in a Sheep Model |
Circulation, Oct 2008; 118: S_543 |
pressure catheters |
sheep |
Sarcomere Function and Regulation |
| Rastogi S, Sharov VG, Mishra S, Gupta RC, Blackburn B, Belardinelli L, Stanley WC, Sabbah HN |
Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure |
Am J Physiol Heart Circ Physiol, Nov 2008; 295: H2149 - H2155 |
catheter-tip micromanometers |
dog |
ventricular remodeling; sodium current; transcription factors; left ventricle |
| Richer L-P, Vinet A, Kus T, Cardinal R, Ardell JL, Armour JA |
α-Adrenoceptor blockade modifies neurally induced atrial arrhythmias |
Am J Physiol Regulatory Integrative Comp Physiol, Oct 2008; 295: R1175 - R1180 |
Millar electronic pressure sensors |
dog |
neuromodulation; cardiac nervous system; ganglionic blockade |
| Voeller RK, Zierer A, Lall SC, Sakamoto S, Chang N-L, Schuessler RB, Moon MR, Damiano Jr RJ |
The effects of the Cox maze procedure on atrial function |
J. Thorac. Cardiovasc. Surg., November 2008; 136: 1257 - 1264 |
SPR-766 |
pig |
Cardiopulmonary Support and Physiology |
| Fumoto H, Gillinov AM, Ootaki Y, Akiyama M, Saeed D, Horai T, Ootaki C, Vince, DG, Popovic ZB, Dessoffy R, Massiello A, Catanese J, Fukamachi K |
A novel device for left atrial appendage exclusion: The third-generation atrial exclusion device |
J. Thorac. Cardiovasc. Surg., October 2008; 136: 1019 - 1027 |
SPC-350 |
dog |
Evolving Technology |
| Nonaka M, Marui A, Fukuoka M, Shimamoto T, Masuyama S, Ikeda T, Komeda M |
Differences in mitral valve-left ventricle dimensions between a beating heart and during saline injection test |
Eur. J. Cardiothorac. Surg., October 2008; 34: 755 - 759 |
micromanometer pressure transducer |
dog |
Saline injection test (regurgitation test) • Mitral valvuloplasty • Mitral leaflets • Mitral annulus • Saddle shape |
| Suzuki G, yer V, Cimato T, Canty Jr JM |
Pravastatin Improves Function in Hibernating Myocardium by Mobilizing CD133+ and cKit+ Bone Marrow Progenitor Cells and Promoting Myocytes to Reenter the Growth Phase of the Cardiac Cell Cycle |
Circ. Res., Dec 2008; doi:10.1161/CIRCRESAHA.108.188730 |
Millar catheter |
pig |
statins • hibernating myocardium • cardiac repair • bone marrow progenitor cells |
| Rolland P-H, de Lagausie P, Stathopoulos E, Leprètre O, Viudes G, Gorincour G, Hery G, de Magnée C, Paut O, Guys J-M |
Phasic hemodynamics and reverse blood flows in the aortic isthmus and pulmonary arteries of preterm lambs with pulmonary vascular dysfunction |
Am J Physiol Heart Circ Physiol, Dec 2008; 295: H2231 - H2241 |
SPR-249, SPR-612 |
sheep |
fetal pulmonary circulation; congenital diaphragmatic hernia; pulmonary reverse flows; pulsatile impedance; endothelin receptor inhibitor |
| Olson AK, Hyyti OM, Cohen GA, Ning X-H, Sadilek M, Isern N, Portman MA |
Superior cardiac function via anaplerotic pyruvate in the immature swine heart after cardiopulmonary bypass and reperfusion |
Am J Physiol Heart Circ Physiol, Dec 2008; 295: H2315 - H2320 |
Millar high-fidelity micromanometer |
pig |
cardiac metabolism; pyruvate carboxylation; pyruvate decarboxlyation; citric acid cycle; tricarboxylic acid cycle |
| Turcott RG, Pavek TJ |
Hemodynamic sensing using subcutaneous photoplethysmography |
Am J Physiol Heart Circ Physiol, Dec 2008; 295: H2560 - H2572 |
SPC-340 |
dog |
defibrillator; pacemaker; sensor; atrioventricular delay; arrhythmia |
| Potapova IA, Doronin SV, Kelly DJ, Rosen AB, Schuldt AJT, Lu Z, Kochupura PV, Robinson RB, Rosen MR, Brink PR, Gaudette GR, Cohen IS |
Enhanced recovery of mechanical function in the canine heart by seeding an extracellular matrix patch with mesenchymal stem cells committed to a cardiac lineage |
Am J Physiol Heart Circ Physiol, Dec 2008; 295: H2257 - H2263 |
pressure transducer |
dog |
human mesenchymal stem cells; myocyte structure; cardiac contractile function; myogenesis; cardiac regeneration; myocardium; heart failure |
| Rastogi S, Imai M, Sharov VG, Mishra S, Sabbah HN |
Darbepoetin-α prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure |
Am J Physiol Heart Circ Physiol, Dec 2008; 295: H2475 - H2482 |
catheter-tip micromanometers |
dog |
erythropoietin; anemia; ventricular remodeling; stem cells |
| Koizumi K, Shin H, Toru Matayoshi T, Yozu R |
Comparison of active and passive coronary perfusion in off-pump coronary artery bypass grafting |
Interactive CardioVascular and Thoracic Surgery, Dec 2008; 7: 977 - 980 |
SPC-320 |
dog |
CABG; Off-pump coronary artery bypass; Myocardial protection; Myocardial ischemia |
---------------------------------------------Published in 2007---------------------------------------------
|
| Timmers L, Sluijter JPG, Verlaan CWJ, Steendijk P, Cramer MJ, Emons M, Strijder C, Gründeman PF, Sze SK, Hua L, Piek JJ, Borst C, Pasterkamp G, Kleijn DPV |
Cyclooxygenase-2 Inhibition Increases Mortality, Enhances Left Ventricular Remodeling, and Impairs Systolic Function After Myocardial Infarction in the Pig |
Circulation, Jan 2007; 115: 326 - 332 |
pressure-tipped Millar catheter |
pig |
myocardial infarction • heart failure • remodeling • enzymes |
| Axelsson M, Dang Q, Pitsillides K, Munns S, Hicks J, Kassab GS |
A novel, fully implantable, multichannel biotelemetry system for measurement of blood flow, pressure, ECG, and temperature |
J Appl Physiol, Mar 2007; 102: 1220 - 1228 |
1 mm in diameter, 3F, |
pig, alligator |
chronic measurements; Doppler flow; telemetry; swine; alligator |
| Schmidt MR, Smerup M, Konstantinov IE, Shimizu M, Li J, Cheung M, White PA, Kristiansen SB, Sorensen K, Dzavik V, Redington AN, Kharbanda RK |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning |
Am J Physiol Heart Circ Physiol, Apr 2007; 292: H1883 - H1890 |
integrated micromanometer, PVAN |
pig |
remote preconditioning; cardioprotection |
| Lü F, Iaizzo PA, Benditt DG, Mehra R, Warman EN, McHenry BT |
Isolated Atrial Segment Pacing: An Alternative to His Bundle Pacing After Atrioventricular Junctional Ablation |
J Am Coll Cardiol, 2007; 49:1443-1449, doi:10.1016/j.jacc.2006.12.034 (Published online 20 March 2007). |
MPC-500 |
pig |
isolated working swine heart |
| Kotani Y, Ishino K, Osaki S, Honjo O, Suezawa T, Kanki K, Yutani C, Sano S |
Efficacy of MCI-186, a free-radical scavenger and antioxidant, for resuscitation of nonbeating donor hearts |
J. Thorac. Cardiovasc. Surg., June 2007; 133: 1626 - 1632 |
3F pressure-tip catheter |
pig |
transplantation |
| Cortina C, Bermejo J, Yotti R, Desco MM, Rodríguez-Pérez D, Antoranz C, Rojo-Álvarez JL, Garcia D, García-Fernández MA, Fernández-Avilés F |
Noninvasive Assessment of the Right Ventricular Filling Pressure Gradient |
Circulation, Aug 2007; 116: 1015 - 1023 |
Micromanometer catheters |
pig |
RV driving filling force |
| Shuros AC, Salo RW, Florea VG, Pastore J, Kuskowski MA, Chandrashekhar Y, Anand IS |
Ventricular Preexcitation Modulates Strain and Attenuates Cardiac Remodeling in a Swine Model of Myocardial Infarction |
Circulation, Sep 2007; 116: 1162 - 1169 |
LV pressures (Millar Instruments) |
pig |
myocardial infarction • remodeling • heart failure • myocardial contraction • electrical stimulation |
| Berberian G, Quinn TA, Cabreriza SE, Kenny JS, Garofalo CA, Weinberg AD, Spotnitz HM |
Left ventricular pacing site and timing optimization during biventricular pacing using a multielectrode patch in pigs |
J. Thorac. Cardiovasc. Surg., September 2007; 134: 574 - 578 |
5F micromanometer catheters |
pig |
Dual-chamber mode biventricular pacing |
| Ewy GA, Zuercher M, Hilwig RW, Sanders AB, Berg RA, Otto CW, Hayes MM, Kern KB |
Improved Neurological Outcome With Continuous Chest Compressions Compared With 30:2 Compressions-to-Ventilations Cardiopulmonary Resuscitation in a Realistic Swine Model of Out-of-Hospital Cardiac Arrest |
Circulation, Nov 2007; 116: 2525 - 2530 |
MPC-500 |
pig |
ventilations-to-chest-compression algorithm. CPR |
| Ghanta RK, Rangaraj A, Umakanthan R, Lee L, Laurence RG, Fox JA, Bolman III RM, Cohn LH, Chen FY |
Adjustable, Physiological Ventricular Restraint Improves Left Ventricular Mechanics and Reduces Dilatation in an Ovine Model of Chronic Heart Failure |
Circulation, Mar 2007; 115: 1201 - 1210 |
High-fidelity micromanometers |
sheep |
restraint level |
| Flewitt JA, Hobson TN, Wang Jr J, Johnston CR, Shrive NG, Belenkie I, Parker KH, Tyberg JV |
Wave intensity analysis of left ventricular filling: application of windkessel theory |
Am J Physiol Heart Circ Physiol, Jun 2007; 292: H2817 - H2823 |
8-Fr, model PC-480, SPR-524 |
dog |
transmitral flow; mitral velocity; E wave; diastolic suction |
| Joudinaud TM, Kegel CL, Flecher EM, Weber PA, Lansac E, Hvass U, Duran CMG |
The papillary muscles as shock absorbers of the mitral valve complex. An experimental study |
Eur. J. Cardiothorac. Surg., July 2007; 32: 96 - 101 |
TCB 600 and MIKRO-TIP pressure transducers, model 510 |
sheep |
Anatomy • Mitral valve • Regurgitation • Papillary muscles • Surgery |
| Carlhäll C, Kindberg K, Wigström L, Daughters GT, Miller DC, Karlsson M, Ingels Jr NB |
Contribution of mitral annular dynamics to LV diastolic filling with alteration in preload and inotropic state |
Am J Physiol Heart Circ Physiol, Sep 2007; 293: H1473 - H1479 |
SPC-500 |
sheep |
diastolic function; inotropic augmentation; mitral annular excursion; preload reduction; regional left ventricular filling properties |
| Beeri R, Yosefy C, Guerrero JL, Abedat S, Handschumacher MD, Stroud RE, Sullivan S, Chaput M, Gilon D, Vlahakes GJ, Spinale FG, Hajjar RJ, Levine RA |
Early Repair of Moderate Ischemic Mitral Regurgitation Reverses Left Ventricular Remodeling: A Functional and Molecular Study |
Circulation, Sep 2007; 116: I-288 - I-293 |
high-fidelity micromanometer-tipped catheter |
sheep |
mitral valve • myocardial infarction • regurgitation • remodeling • surgery |
| Hung J, Chaput M, Guerrero JL, Handschumacher MD, Papakostas L, Sullivan S, Solis J, Levine RA |
Persistent Reduction of Ischemic Mitral Regurgitation by Papillary Muscle Repositioning: Structural Stabilization of the Papillary Muscle–Ventricular Wall Complex |
Circulation, Sep 2007; 116: I-259 - I-263 |
micromanometer-tipped Millar catheter |
sheep |
mitral regurgitation • left ventricular remodeling |
| Mau J, Menzie S, Ward M, Bundgaard H, Hunyor S |
Time-dependent response of both ventricles after septal ablation: Implications for biventricular support after left ventricular assist device placement |
J. Thorac. Cardiovasc. Surg., September 2007; 134: 579 - 586 |
5F Millar catheter-tip pressure transducer |
sheep |
percutaneous transluminal septal myocardial ablation |
| Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Acevedo-Bolton G, Guttman MA, Ozturk C, McVeigh ER, Saloner DA, Wallace AW, Ratcliffe MB |
Endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm increases systolic circumferential shortening in sheep |
J. Thorac. Cardiovasc. Surg., October 2007; 134: 1017 - 1024 |
SPC-350 |
sheep |
Dor procedure |
| Maruo T, Nakatani S, Jin Y, Uemura K, Sugimachi M, Ueda-Ishibashi H, Kitakaze M, Ohe T, Sunagawa K, Miyatake K |
Evaluation of transmural distribution of viable muscle by myocardial strain profile and dobutamine stress echocardiography |
Am J Physiol Heart Circ Physiol, Feb 2007; 292: H921 - H927 |
MPC-500 |
dog |
echocardiography |
| Jin Y-T, Hasebe N, Matsusaka T, Natori S, Ohta T, Tsuji S, Kikuchi K |
Magnesium attenuates isoproterenol-induced acute cardiac dysfunction and β-adrenergic desensitization |
Am J Physiol Heart Circ Physiol, Mar 2007; 292: H1593 - H1599 |
SPC-350 |
dog |
calcium overload; free radical; dog, left ventricular; tau |
| Hobson TN, Flewitt JA, Belenkie I, Tyberg JV |
Wave intensity analysis of left atrial mechanics and energetics in anesthetized dogs |
Am J Physiol Heart Circ Physiol, Mar 2007; 292: H1533 - H1540 |
2-F micromanometer |
dog |
hemodynamics; left atrium; A wave; Ar wave; Doppler echocardiography |
| Wang J, Khoury DS, Thohan V, Torre-Amione G, Nagueh SF |
Global Diastolic Strain Rate for the Assessment of Left Ventricular Relaxation and Filling Pressures |
Circulation, Mar 2007; 115: 1376 - 1383 |
7F |
dog |
Global SRIVR by 2-dimensional speckle tracking |
| Fukuoka M, Nonaka M, Masuyama S, Shimamoto T, Tambara K, Yoshida H, Ikeda T, Komeda M |
Chordal "translocation" for functional mitral regurgitation with severe valve tenting: An effort to preserve left ventricular structure and function |
J. Thorac. Cardiovasc. Surg., April 2007; 133: 1004 - 1011 |
MPC-500 |
dog |
chordae tendineae |
| Hori Y, Kano T, Hoshi F, Higuchi S |
Relationship between tissue Doppler-derived RV systolic function and invasive hemodynamic measurements |
Am J Physiol Heart Circ Physiol, Jul 2007; 293: H120 - H125 |
3.5-Fr micromanometer-tipped catheter |
dog |
dog; right ventricle; systolic myocardial velocity; tissue Doppler imaging |
| Coppola BA, Covell JW, McCulloch AD, Omens JH |
Asynchrony of ventricular activation affects magnitude and timing of fiber stretch in late-activated regions of the canine heart |
Am J Physiol Heart Circ Physiol, Jul 2007; 293: H754 - H761 |
8-Fr pigtail micromanometer catheter with a lumen |
dog |
ventricular pacing; mechanical activation; fiber stretch; dyssynchrony |
| Akar FG, Nass RD, Hahn S, Cingolani E, Shah M, Hesketh GG, DiSilvestre D, Tunin RS, Kass DA, Tomaselli GF |
Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure |
Am J Physiol Heart Circ Physiol, Aug 2007; 293: H1223 - H1230 |
Millar catheter |
dog |
electrical remodeling; connexin; arrhythmias |
| Jaber WA, Lam CSP, Meyer DM, Redfield MM |
Revisiting methods for assessing and comparing left ventricular diastolic stiffness: impact of relaxation, external forces, hypertrophy, and comparators |
Am J Physiol Heart Circ Physiol, Nov 2007; 293: H2738 - H2746 |
high-fidelity micromanometer-tipped catheter |
dog |
hemodynamics; heart failure; methods; pericardium |
| Johnson L, Kim HK, Tanabe M, Gorcsan J, Schwartzman D, Shroff SG, Pinsky MR |
Differential effects of left ventricular pacing sites in an acute canine model of contraction dyssynchrony |
Am J Physiol Heart Circ Physiol, Nov 2007; 293: H3046 - H3055 |
MPC-500 |
dog |
cardiac resynchronization therapy; left ventricular global performance; myocardial strain; tissue Doppler imaging |
| Wang J, Khoury DS, Yue Y, Torre-Amione G, Nagueh SF |
Left Ventricular Untwisting Rate by Speckle Tracking Echocardiography |
Circulation, Nov 2007; 116: 2580 - 2586 |
7F |
dog |
dobutamine and esmolol infusion |
| da Cunha DNQ, Hamlin RL, Billman GE, Carnes CA |
n-3 (omega-3) polyunsaturated fatty acids prevent acute atrial electrophysiological remodeling |
British Journal of Pharmacology 150, 281 - 285 (01 Feb 2007) |
SPC-350 |
dog |
antiarrhythmic agents, atrial function, ECG, atrial fibrillation, n-3 polyunsaturated fatty acids, n-6 polyunsaturated fatty acids |
| Kast R, Schirok H, Figueroa-Pérez S, Mittendorf J, Gnoth MJ, Apeler H, Lenz J, Franz JK, Knorr A, Hütter J, Lobell M, Zimmermann K, Münter K, Augstein KH, Ehmke H, Stasch JP |
Cardiovascular effects of a novel potent and highly selective azaindole-based inhibitor of Rho-kinase |
British Journal of Pharmacology 152, 1070 - 1080 (15 Oct 2007) |
PC-350 |
rat, dog |
Rho-kinase inhibitor, in vitro selectivity, vasorelaxation, blood pressure, heart rate, hypertension |
| |
---------------------------------------------Published in 2006---------------------------------------------
|
| Weinstock J, Maron BJ, Song C, Mane PP, Estes NAM, Link MS |
Failure of Commercially Available Chest Wall Protectors to Prevent Sudden Cardiac Death Induced by Chest Wall Blows in an Experimental Model of Commotio Cordis |
PEDIATRICS (doi:10.1542/peds.2005-1270) |
Millar Mikrotip |
pig |
death • sudden cardiac • arrhythmia • ventricular fibrillation • pediatrics • commotio cordis • athletes |
| Okere IC, McElfresh TA, Brunengraber DZ, Martini W, Sterk JP, Huang H, Chandler MP, Brunengraber H, Stanley WC |
Differential effects of heptanoate and hexanoate on myocardial citric acid cycle intermediates following ischemia-reperfusion |
J Appl Physiol, Jan 2006; 100: 76 - 82 |
high-fidelity manometer-tipped catheter |
pig |
anaplerosis; fatty acids; heart; metabolism; mitochondria; pyruvate dehydrogenase |
| Schwartz LM, Lagranha CJ |
Ischemic postconditioning during reperfusion activates Akt and ERK without protecting against lethal myocardial ischemia-reperfusion injury in pigs |
Am J Physiol Heart Circ Physiol, Mar 2006; 290: H1011 - H1018 |
SPC-780C |
pig |
swine; signal transduction; extracellular signal-regulated kinase 1/2; infarction; ischemic preconditioning |
| Berberian G, Quinn TA, Cabreriza SE, Garofalo CA, Barrios DM, Weinberg AD, Spotnitz HM |
Load dependence of cardiac output in biventricular pacing: Left ventricular volume overload in pigs |
J. Thorac. Cardiovasc. Surg., Mar 2006; 131: 666 - 670 |
5F micromanometer catheters |
pig |
perioperative temporary biventricular pacing |
| Weinstock J, Maron BJ, Song C, Mane PP, Estes III NAM, Link MS |
Failure of Commercially Available Chest Wall Protectors to Prevent Sudden Cardiac Death Induced by Chest Wall Blows in an Experimental Model of Commotio Cordis |
Pediatrics, Apr 2006; 117: e656 - e662 |
Millar catheter |
pig |
death • sudden cardiac • arrhythmia • ventricular fibrillation • pediatrics • commotio cordis • athletes |
| Barrabés JA, Garcia-Dorado D, Agulló L, Rodríguez-Sinovas A, Padilla F, Trobo L, Soler-Soler J |
Intracoronary infusion of Gd3+ into ischemic region does not suppress phase Ib ventricular arrhythmias after coronary occlusion in swine |
Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2344 - H2350 |
micromanometer-tipped catheter |
pig |
ischemia; stretch; mechanoelectrical coupling; ventricular dilation; sudden death |
| Quinn TA, Berberian G, Cabreriza SE, Maskin LJ, Weinberg AD, Holmes JW, Spotnitz HM |
Effects of sequential biventricular pacing during acute right ventricular pressure overload |
Am J Physiol Heart Circ Physiol, Nov 2006; 291: H2380 - H2387 |
Solid-state pressure transducer catheters 5-Fr |
pig |
ventricular mechanics; interventricular synchrony; cardiac output; perioperative pacing; cardiac resynchronization therapy |
| Tozzi P, Hayoz D, Sinisclachi G, von Segesser LK |
VERMEIDUNG VON MYOINTIMALER HYPERPLASIE IN EINEM PULMONALARTERIELLEN NIEDERFLUSSANASTOMOSEMODELL BEIM SCHWEIN |
SwissPerfusion, November 2006 |
MPC-500 |
schwein |
Gefäßanastomosen, Intima-Hyperplasie, Anastomosen-Stenose, Wandscherkräfte |
| Guccione JM, Walker JC, Beitler JR, Moonly SM, Zhang P, Guttman MA, Ozturk C, McVeigh ER, Wallace AW, Saloner DA, Ratcliffe MB |
The effect of anteroapical aneurysm plication on end-systolic three-dimensional strain in the sheep: A magnetic resonance imaging tagging study |
J. Thorac. Cardiovasc. Surg., Mar 2006; 131: 579 - 586 |
SPC-320 |
sheep |
left ventricular aneurysm |
| Langer F, Rodriguez F, Cheng A, Ortiz S, Nguyen TC, Zasio MK, Liang D, Daughters GT, Ingels NB, Miller DC |
Posterior mitral leaflet extension: An adjunctive repair option for ischemic mitral regurgitation? |
J. Thorac. Cardiovasc. Surg., Apr 2006; 131: 868 - 877 |
SPC-500 |
sheep |
restricted leaflet (Carpentier type IIIb) systolic closing motion |
| Leshnower BG, Sakamoto H,Zeeshan A, Parish LM, Hinmon R, Plappert T, Jackson BM, Gorman III JH, Gorman RC |
Role of acetaminophen in acute myocardial infarction |
Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2424 - H2431 |
SPC-350S, SPR-524 |
sheep, rabbit |
reperfusion therapy; nonsteroidal anti-inflammatory drugs; sonomicrometry array localization |
| Messas E, Yosefy C, Chaput M, Guerrero JL, Sullivan S, Menasché P, Carpentier A, Desnos M, Hagege AA, Vlahakes GJ, Levine RA |
Chordal Cutting Does Not Adversely Affect Left Ventricle Contractile Function |
Circulation, Jul 2006; 114: I-524 - I-528 |
5-F micromanometer-tipped Millar catheter |
sheep |
chordae • echocardiography • mitral valve • regurgitation |
| Kilic A, Li T, Nolan TDC,Nash JR, Li S, Prastein DJ, Schwartzbauer G, Moainie SL, Yankey GK, DeFilippi C, Wu Z, Griffith BP |
Strain-related regional alterations of calcium-handling proteins in myocardial remodeling |
J. Thorac. Cardiovasc. Surg., Oct 2006; 132: 900 - 908 |
SPC-350 |
sheep |
postinfarction cardiac remodeling |
| Sakamoto H, Parish LM, Hamamoto H, Enomoto Y, Zeeshan A, Plappert T, Jackson BM, St. John-Sutton MG, Gorman RC, Gorman III JH |
Effects of hemodynamic alterations on anterior mitral leaflet curvature during systole |
J. Thorac. Cardiovasc. Surg., Dec 2006; 132: 1414 - 1419 |
SPC-350 |
sheep |
phenylephrine hydrochloride infusion |
| Wang J-J, Flewitt JA, Shrive NG, Parker KH, Tyberg JV |
Systemic venous circulation. Waves propagating on a windkessel: relation of arterial and venous windkessels to systemic vascular resistance |
Am J Physiol Heart Circ Physiol, Jan 2006; 290: H154 - H162 |
2F |
dog |
systemic circulation |
| Wu G, Du Z, Hu C, Zheng Z, Zhan C, Ma H, Fang D, Ahmed KT, Laham RJ, Hui JCK, Lawson WE |
Angiogenic effects of long-term enhanced external counterpulsation in a dog model of myocardial infarction |
Am J Physiol Heart Circ Physiol, Jan 2006; 290: H248 - H254 |
pressure transducer catheter |
dog |
angiogenesis; collateral circulation; growth factors; infarction; ventricular function |
| Hong T-T, Huang J, Lucchesi BR |
Effect of thrombolysis on myocardial injury: recombinant tissue plasminogen activator vs. alfimeprase |
Am J Physiol Heart Circ Physiol, Mar 2006; 290: H959 - H967 |
Millar Mikro-Tip pressure-sensitive transducer catheter |
dog |
myocardium; reperfusion injury; thrombolytic agents |
| Verbeek XAAM, Auricchio A, Yu Y, Ding J, Pochet T, Vernooy K, Kramer A, Spinelli J, Prinzen FW |
Tailoring cardiac resynchronization therapy using interventricular asynchrony. Validation of a simple model |
Am J Physiol Heart Circ Physiol, Mar 2006; 290: H968 - H977 |
SPC-780C |
dog |
bundle-branch block; conduction; heart failure; pacing; ventricles |
| Yong-Mei Cha, Petras P. Dzeja, Margaret M. Redfield, Win K. Shen, and Andre Terzic |
Bioenergetic protection of failing atrial and ventricular myocardium by vasopeptidase inhibitor omapatrilat |
Am J Physiol Heart Circ Physiol, Apr 2006; 290: H1686 - H1692 |
high-fidelity Millar catheter |
dog |
atria; ventricle; adenylate kinase; creatine kinase; energy metabolism; heart failure |
| Popovic ZB, Prasad A, Garcia MJ, Arbab-Zadeh A, Borowski A, Dijk E, Greenberg NL, Levine BD, Thomas JD |
Relationship among diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness |
Am J Physiol Heart Circ Physiol, Apr 2006; 290: H1454 - H1459 |
micromanometer-tipped catheter |
dog |
aging; diastolic function; pulmonary capillary wedge pressure; isovolumic relaxation |
| Cannesson M, Jacques D, Pinsky MR, Gorcsan III J |
Effects of modulation of left ventricular contractile state and loading conditions on tissue Doppler myocardial performance index |
Am J Physiol Heart Circ Physiol, May 2006; 290: H1952 - H1959 |
MPC-500 |
dog |
contractility; echocardiography; ventricles |
| Kroeker CAG, Adeeb S, Shrive NG, Tyberg JV |
Compression induced by RV pressure overload decreases regional coronary blood flow in anesthetized dogs |
Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2432 - H2438 |
6-Fr micromanometer-tipped catheters |
dog |
diastole; mechanics; microspheres; right ventricle; left ventricle; finite element modeling; myocardial ischemia |
| Morita H, Khanal S, Rastogi S, Suzuki G, Imai M, Todor A, Sharov VG, Goldstein S, O'Neill TP, Sabbah HN |
Selective matrix metalloproteinase inhibition attenuates progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure |
Am J Physiol Heart Circ Physiol, Jun 2006; 290: H2522 - H2527 |
catheter-tip micromanometers |
dog |
hemodynamics; PG-530742; left ventricular ejection fraction |
| George I, Yi G-H, Schulman AR, Morrow BT, Cheng Y, Gu A, Zhang G, Oz MC, Burkhoff D, Wang J |
A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia |
Am J Physiol Heart Circ Physiol 291, Sep 2006: H1126-H1137, 2006 |
SPC-360S |
dog |
coronary; blood; nitric oxide inhibitor |
| Yada T, Shimokawa H, Hiramatsu O, Haruna Y, Morita Y, Kashihara N, Shinozaki Y, Mori H, Goto M, Ogasawara Y, Kajiya F |
Cardioprotective role of endogenous hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo |
Am J Physiol Heart Circ Physiol, Sep 2006; 291: H1138 - H1146 |
SPC-784A |
dog |
endothelium-derived relaxing factor; myocardial infarction; vascular endothelial function |
| Pacella JJ, Villanueva FS |
Effect of Coronary Stenosis on Adjacent Bed Flow Reserve: Assessment of Microvascular Mechanisms Using Myocardial Contrast Echocardiography |
Circulation, Oct 2006; 114: 1940 - 1947 |
high-fidelity micromanometer-tipped catheter |
dog |
flow reserve |
| Kroeker CAG, Adeeb S, Tyberg JV, Shrive NG |
A 2D FE model of the heart demonstrates the role of the pericardium in ventricular deformation |
Am J Physiol Heart Circ Physiol, Nov 2006; 291: H2229 - H2236 |
8-Fr micromanometer-tipped catheters |
dog |
ventricular function, right ventricular overload; finite element analysis |
| Cardinal R,Pagé P, Vermeulen M, Bouchard C, Ardell JL, Foreman RD, Armour JA |
Spinal cord stimulation suppresses bradycardias and atrial tachyarrhythmias induced by mediastinal nerve stimulation in dogs |
Am J Physiol Regulatory Integrative Comp Physiol, Nov 2006; 291: R1369 - R1375 |
Millar electronic pressure sensors |
dog |
intrinsic cardiac nervous system |
| Sun Y, Belenkie I, Wang J-J, Tyberg JV |
Assessment of right ventricular diastolic suction in dogs with the use of wave intensity analysis |
Am J Physiol Heart Circ Physiol, Dec 2006; 291: H3114 - H3121 |
SPC-471, SPR-524 |
dog |
diastole; hemodynamics; tricuspid valve; velocity; pressure |
| |
|
|
|
|
|
---------------------------------------------Published in 2005---------------------------------------------
|
| Kadem L, Dumesnil JG, Rieu R, Durand L-G, Garcia D, Pibarot P |
Impact of systemic hypertension on the assessment of aortic stenosis |
Heart 2005;91:354-361 |
multisensor Millar catheter |
pig |
aortic stenosis; Doppler echocardiography; haemodynamic function; hypertension; left ventricular function |
| Berg RA, Sorrell VL, Kern KB, Hilwig RW, Altbach MI, Hayes MM, Bates KA, Ewy GA |
Magnetic Resonance Imaging During Untreated Ventricular Fibrillation Reveals Prompt Right Ventricular Overdistention Without Left Ventricular Volume Loss |
Circulation, Mar 2005; 111: 1136 - 1140 |
MPC-500 |
pig |
cardiopulmonary resuscitation • heart arrest • hemodynamics • magnetic resonance imaging • ventricular fibrillation |
| Nielsen SL, Hansen SB, Nielsen KO, Nygaard H, Paulsen PK, Hasenkam JM |
Imbalanced chordal force distribution causes acute ischemic mitral regurgitation: Mechanistic insights from chordae tendineae force measurements in pigs |
J. Thorac. Cardiovasc. Surg., Mar 2005; 129: 525 - 531 |
SPC-350MR |
pig |
echocardiography |
| Deschamps AM, Apple KA, Leonardi AH, McLean JE, Yarbrough WM, Stroud RE, Clark LL, Sample JA, Spinale FG |
Myocardial Interstitial Matrix Metalloproteinase Activity Is Altered by Mechanical Changes in LV Load: Interaction With the Angiotensin Type 1 Receptor |
Circ. Res., May 2005; 96: 1110 - 1118 |
7.5 F |
pig |
matrix metalloproteinase • extracellular matrix • angiotensin II type I receptor |
| Yannopoulos D, Nadkarni VM, McKnite SH, Rao A, Kruger K, Metzger A, Benditt DG, Lurie KG |
Intrathoracic Pressure Regulator During Continuous-Chest-Compression Advanced Cardiac Resuscitation Improves Vital Organ Perfusion Pressures in a Porcine Model of Cardiac Arrest |
Circulation, Aug 2005; 112: 803 - 811 |
Mikro-Tip Transducer |
pig |
ITPR-CPR, STD-CPR |
| Sengupta PP, Khandheria BK, Korinek J, Wang J, Belohlavek M |
Biphasic tissue Doppler waveforms during isovolumic phases are associated with asynchronous deformation of subendocardial and subepicardial layers |
J Appl Physiol, Sep 2005; 99: 1104 - 1111 |
manometer-tipped catheters |
pig |
myocardial contraction; mechanics; echocardiography; tissue Doppler imaging; isovolumic contraction; isovolumic relaxation |
| Ovchinnikov V, Suzuki G, Canty Jr JM, Fallavollita JA |
Blunted functional responses to pre- and postjunctional sympathetic stimulation in hibernating myocardium |
Am J Physiol Heart Circ Physiol, Oct 2005; 289: H1719 - H1728 |
transducer-tipped catheter |
pig |
hibernation; sympathetic nerves; catecholamines; myocardial contraction |
| Iyer VS, Canty Jr JM |
Regional Desensitization of ß-Adrenergic Receptor Signaling in Swine With Chronic Hibernating Myocardium |
Circ. Res., Oct 2005; 97: 789 - 795 |
5F end-hole micromanometer |
pig |
ß-receptors • hibernating myocardium • chronic ischemic heart disease • adenylyl cyclase |
| Pandalai PK, Lyons JM, Duffy JY, McLean KM, Wagner CJ, Merrill WH, Pearl JM, Akhter SA |
Role of the ß-adrenergic receptor kinase in myocardial dysfunction after brain death |
J. Thorac. Cardiovasc. Surg., Oct 2005; 130: 1183 - 1189 |
Pressure transducer-tipped 2F or 3F catheters |
pig |
cyclic adenosine monophosphate |
| Yotti R, Bermejo J, Antoranz JC, Desco MM, Cortina C, Rojo-Álvarez JL, Allué C, Martín L, Moreno M, Serrano JA, Muñoz R, García-Fernández MA |
A Noninvasive Method for Assessing Impaired Diastolic Suction in Patients With Dilated Cardiomyopathy |
Circulation, Nov 2005; 112: 2921 - 2929 |
needle micromanometer, dual-micromanometer catheter (3-cm sensor spacing, Millar Instruments) |
pig |
cardiomyopathy • echocardiography • heart failure • imaging • diastole |
| Stanley WC, Morgan EE, Huang H, McElfresh TA, Sterk JP, Okere IC, Chandler MP, Cheng J, Dyck JRB, Lopaschuk GD |
Malonyl-CoA decarboxylase inhibition suppresses fatty acid oxidation and reduces lactate production during demand-induced ischemia |
Am J Physiol Heart Circ Physiol, Dec 2005; 289: H2304 - H2309 |
high-fidelity manometer-tipped catheter |
pig |
carnitine palmitoyltransferase-I; glucose; heart; lactate; myocardium |
| Rondelet B, Kerbaul F, Van Beneden R, Hubloue I, Huez S, Fesler P, Remmelink M, Brimioulle S, Salmon I, Naeije R |
Prevention of pulmonary vascular remodeling and of decreased BMPR-2 expression by losartan therapy in shunt-induced pulmonary hypertension |
Am J Physiol Heart Circ Physiol, Dec 2005; 289: H2319 - H2324 |
SPC-350 |
pig |
left-to-right shunt; angiotensin II; endothelin-1; angiopoietin; bone morphogenetic protein receptor-2 |
| Santana DB, Barra JG, Grignola JC, Ginés FF, Armentano RL |
Pulmonary artery smooth muscle activation attenuates arterial dysfunction during acute pulmonary hypertension |
J Appl Physiol 98: 605-613, 2005. |
SPC-370, 7F |
sheep |
buffering function; arterial wall viscoelasticity; characteristic impedance |
| Santana DB, Barra JG, Grignola JC, Ginés FF, Armentano RL |
Pulmonary artery smooth muscle activation attenuates arterial dysfunction during acute pulmonary hypertension |
J Appl Physiol 98: 605-613, 2005. |
SPC-370, 7F |
sheep |
buffering function; arterial wall viscoelasticity; characteristic impedance |
| Harrington KB, Rodriguez F, Cheng A, Langer F, Ashikaga H, Daughters GT, Criscione JC, Ingels NB, Miller DC |
Direct measurement of transmural laminar architecture in the anterolateral wall of the ovine left ventricle: new implications for wall thickening mechanics |
Am J Physiol Heart Circ Physiol, Mar 2005; 288: H1324 - H1330 |
SPC-500 |
sheep |
cardiac microstructure; sheets |
| Enomoto Y, Gorman III JH, Moainie SL, Guy TS, Jackson BM, Parish LM, Plappert T, Zeeshan A, St. John-Sutton MG, Gorman RC |
Surgical treatment of ischemic mitral regurgitation might not influence ventricular remodeling |
J. Thorac. Cardiovasc. Surg., Mar 2005; 129: 504 - 511 |
SPC-350 |
sheep |
post-infarction remodeling |
| Cheng A, Langer F,Rodriguez F, Criscione JC, Daughters GT, Miller DC, Ingels Jr NB |
Transmural cardiac strains in the lateral wall of the ovine left ventricle |
Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1546 - H1556 |
MPC-500 |
sheep |
wall thickening; left ventricle myocardium; systolic function |
| Hashimoto I, Li X-K, Hejmadi Bhat AH, Jones M, Sahn DJ |
Quantitative assessment of regional peak myocardial acceleration during isovolumic contraction and relaxation times by tissue Doppler imaging |
Heart, Jun 2005; 91: 811 - 816 |
SPC-350 |
sheep |
contractility; echocardiography; relaxation; ventricle |
| Langer F, Rodriguez F, Ortiz S, Cheng A, Nguyen TC, Zasio MK, Liang D, Daughters GT, Ingels NB, Miller DC |
Subvalvular Repair: The Key to Repairing Ischemic Mitral Regurgitation? |
Circulation, Aug 2005; 112: I-383 - I-389 |
SPC-500 |
sheep |
ischemic mitral regurgitation • mitral valve • mitral valve repair |
| Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Fata B, Hsu EW, Saloner D, Guccione JM |
MRI-based finite-element analysis of left ventricular aneurysm |
Am J Physiol Heart Circ Physiol, Aug 2005; 289: H692 - H700 |
SPC-320 |
sheep |
tagged magnetic resonance imaging; computational modeling; diffusion tensor magnetic resonance imaging; ventricular remodeling; congestive heart failure |
| Langeland S, D’hooge J, Wouters PF, Leather HA, Claus P, Bijnens B, Sutherland GR |
Experimental Validation of a New Ultrasound Method for the Simultaneous Assessment of Radial and Longitudinal Myocardial Deformation Independent of Insonation Angle |
Circulation, Oct 2005; 112: 2157 - 2162 |
Millar catheter |
sheep |
echocardiography • strain • angle dependency |
| Martinez RR, Setty S, Zong P, Tune JD, Downey HF |
Nitric oxide contributes to right coronary vasodilation during systemic hypoxia |
Am J Physiol Heart Circ Physiol, Mar 2005; 288: H1139 - H1146 |
high-fidelity 3-Fr micro-tip catheter pressure transducer |
dog |
right ventricular function; right ventricular oxygen balance; myocardial oxygen consumption |
| Xu J, Kussmaul W, Kurnik PB, Al-Ahdav M, Pelleg A |
Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. V. Role of purinergic receptors |
Am J Physiol Regulatory Integrative Comp Physiol, Mar 2005; 288: R651 - R655 |
electronic pressure transducer-tipped catheter |
dog |
P2X; 2',3'-O-(2,4,6-trinitrophenyl)-ATP; diinosine pentaphosphate; vasovagal syncope |
| Lyseggen E, Rabben SI, Skulstad H, Urheim S, Risoe C, Smiseth OA |
Myocardial Acceleration During Isovolumic Contraction: Relationship to Contractility |
Circulation, Mar 2005; 111: 1362 - 1369 |
MPC-500 |
dog |
echocardiography • ischemia • contractility • myocardial contraction • acceleration |
| Corvera JS, Kin H, Dobson GP, Kerendi F, Halkos ME, Katzmark S, Payne CS, Zhao Z-Q, Guyton RA, Vinten-Johansen J |
Polarized arrest with warm or cold adenosine/lidocaine blood cardioplegia is equivalent to hypothermic potassium blood cardioplegia |
J. Thorac. Cardiovasc. Surg., Mar 2005; 129: 599 - 606 |
MPC-500 |
dog |
myocardial protection, cardioplegia |
| Caswell JE, Strange MB, Rimmer III DM, Gibson MF, Cole P, Lefer DJ |
A novel hemoglobin-based blood substitute protects against myocardial reperfusion injury |
Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1796 - H1801 |
MPC-500, MPC-350 |
dog |
infarction; contractility; neutrophils; ischemia |
| Toyota E, Ogasawara Y, Hiramatsu O, Tachibana H, Kajiya F, Yamamori S, Chilian WM |
Dynamics of flow velocities in endocardial and epicardial coronary arterioles |
Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1598 - H1603 |
SPC-784A |
dog |
microcirculation; circulation; rheology; ischemia |
| Wang Z, Jalali F, Sun Y-H, Wang J-J, Parker KH, Tyberg JV |
Assessment of left ventricular diastolic suction in dogs using wave-intensity analysis |
Am J Physiol Heart Circ Physiol, Apr 2005; 288: H1641 - H1651 |
catheter-tip manometers |
dog |
diastole; hemodynamics; mitral valve; ventricles |
| Urheim S, Rabben SI, Skulstad H, Lyseggen E, Ihlen H, Smiseth OA |
Regional myocardial work by strain Doppler echocardiography and LV pressure: a new method for quantifying myocardial function |
Am J Physiol Heart Circ Physiol, May 2005; 288: H2375 - H2380 |
MPC-500 |
dog |
sonomicrometry; pressure-strain loop |
| Helm RH, Leclercq C, Faris OP, Ozturk C, McVeigh E, Lardo AC, Kass DA |
Cardiac Dyssynchrony Analysis Using Circumferential Versus Longitudinal Strain: Implications for Assessing Cardiac Resynchronization |
Circulation, May 2005; 111: 2760 - 2767 |
1.4F Millar microtip catheter |
dog |
resynchronization therapy • heart failure • bundle-branch block • pacing |
| Wang, Abraham TP, Korinek J, Urheim S, McMahon EM, Belohlavek M |
Delayed Onset of Subendocardial Diastolic Thinning at Rest Identifies Hypoperfused Myocardium |
Circulation, Jun 2005; 111: 2943 - 2950 |
6F micromanometer catheter |
dog |
myocardial relaxation • ischemia • regional blood flow • echocardiography • diastole |
| Uemura K, Kawada T, Kamiya A, Aiba T, Hidaka I, Sunagawa K, Sugimachi M |
Prediction of circulatory equilibrium in response to changes in stressed blood volume |
Am J Physiol Heart Circ Physiol, Jul 2005; 289: H301 - H307 |
SPC-751 |
dog |
β-adrenoceptors; congestive heart failure; G protein-coupled receptor kinase; renin-angiotensin system blockade |
| Mitchell JR, Whitelaw WA, Sas R, Smith ER, Tyberg JV, Belenkie I |
RV filling modulates LV function by direct ventricular interaction during mechanical ventilation |
Am J Physiol Heart Circ Physiol, Aug 2005; 289: H549 - H557 |
SPC-484A |
dog |
right ventricle; left ventricle |
| Gaynor SL, Maniar HS, Bloch JB, Steendijk P, Moon MR |
Right Atrial and Ventricular Adaptation to Chronic Right Ventricular Pressure Overload |
Circulation, Aug 2005; 112: I-212 - I-218 |
MPC-500, SPR-843 |
dog |
atrium • hypertension, pulmonary • pulmonary heart disease |
| Kochupura PV, Azeloglu EU, Kelly DJ, Doronin SV, Badylak SF, Krukenkamp IB, Cohen IS, Gaudette GR |
Tissue-Engineered Myocardial Patch Derived From Extracellular Matrix Provides Regional Mechanical Function |
Circulation, Aug 2005; 112: I-144 - I-149 |
pressure transducer |
dog |
heart failure • surgery • mechanics • remodeling • myocytes |
| Hennan JK, Elokdah H, Leal M, Ji A, Friedrichs GS, Morgan GA, Swillo RE, Antrilli TM, Hreha A, Crandall DL |
Evaluation of PAI-039 [{1-Benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic Acid], a Novel Plasminogen Activator Inhibitor-1 Inhibitor, in a Canine Model of Coronary Artery Thrombosis |
JPET 314:710-716, 2005 |
Mikro-tip catheter |
dog |
electrolytic injury |
| Ashikaga H, Mickelsen SR, Ennis DB, Rodriguez I, Kellman P, Wen H, McVeigh ER |
Electromechanical analysis of infarct border zone in chronic myocardial infarction |
Am J Physiol Heart Circ Physiol, Sep 2005; 289: H1099 - H1105 |
SPC-350 |
dog |
electromechanical mapping; magnetic resonance imaging |
| O’Rourke MF |
New Noninvasive Method for Assessment of Left Ventricular Rotation: Speckle Tracking Echocardiography |
Circulation, Nov 2005; 112: 3149 - 3156 |
MPC-500 |
dog |
echocardiography • ventricles • torsion • magnetic resonance imaging • rotation |
| VanTeeffelen JWGE, Dekker S, Fokkema DS, Siebes M, Vink H, Spaan JAE |
Hyaluronidase treatment of coronary glycocalyx increases reactive hyperemia but not adenosine hyperemia in dog hearts |
Am J Physiol Heart Circ Physiol, Dec 2005; 289: H2508 - H2513 |
SPC-350 |
dog |
coronary circulation; hyaluronidase; dogs |
| Lyseggen E, Skulstad H, Helle-Valle T, Vartdal T, Urheim S, Rabben S, Opdahl A, Ihlen H, Smiseth OA |
Myocardial Strain Analysis in Acute Coronary Occlusion: A Tool to Assess Myocardial Viability and Reperfusion |
Circulation, December 20/27, 2005; 112: 3901 - 3910 |
MPC-500 |
dog |
systolic myocardial compliance |
| |
|
|
|
|
|
---------------------------------------------Published in 2004--------------------------------------------- |
| Canty Jr JM, Suzuki G, Banas MD, Verheyen F, Borgers M, Fallavollita JA |
Hibernating Myocardium: Chronically Adapted to Ischemia but Vulnerable to Sudden Death |
Circulation Research. 2004;94:1142 |
5F Mikro-Tip Catheter |
pig |
hibernating myocardium • sudden cardiac death • ventricular fibrillation |
| Kristo G, Yoshimura Y, Niu J, Keith BJ, Mentzer Jr RM, Bünger R, Lasley RD |
|
| The intermediary metabolite pyruvate attenuates stunning and reduces infarct size in in vivo porcine myocardium |
|
|
5FMikro-Tip catheter |
pig |
| energetics; myocardial ischemia; reperfusion |
|
| Menegazzi JJ, Callaway CW, Sherman LD, Hostler DP, Wang HE, Fertig KC, Logue ES |
|
| Ventricular Fibrillation Scaling Exponent Can Guide Timing of Defibrillation and Other Therapies |
|
|
Mikro-Tip catheter |
pig |
| fibrillation • heart arrest • defibrillation • cardiopulmonary resuscitation |
|
| Pislaru C, Bruce CJ, Anagnostopoulos PC, Allen JL, Seward JB, Pellikka PA, Ritman EL, Greenleaf JF |
Ultrasound Strain Imaging of Altered Myocardial Stiffness |
Circulation. 2004;109:2905-2910.) |
Mikro-Tip Catheter |
pig |
echocardiography • diastole • myocardial infarction • stunning, myocardial • myocardial stiffness |
| Schmidt MR, Smerup M, Kristiansen SB, Bøtker HE, Schmitz O, Hjortdal VE, Sørensen KE, Redington AN |
Maternal Hyperglycemia Improves Fetal Cardiac Function During Tachycardia-Induced Heart Failure in Pigs |
Circulation. 2004;110:2627-2630 |
1.4F high-fidelity pressure catheter |
pig |
heart failure • tachycardia • glucose |
| Castellá M, Buckberg GD |
Reduction of systolic and diastolic dysfunction by retrograde coronary sinus perfusion during off-pump coronary surgery |
J. Thorac. Cardiovasc. Surg., Apr 2004; 127: 1018 - 1025 |
MPC-500 |
pig |
Cardiopulmonary support and physiology, mid-left anterior descending coronary artery ischemia |
| de Zeeuw S, Borst C, Gründeman PF |
Myocardial blood supply through a direct left ventricle–coronary artery shunt is not aided by augmented coronary capacitance |
J. Thorac. Cardiovasc. Surg., Jun 2004; 127: 1751 - 1758 |
pressure catheters |
pig |
Cardiopulmonary support and physiology |
| Rabkin DG, Cabreriza SE, Curtis LJ, Mazer SP, Kanter JP, Weinberg AD, Hordof AJ, Spotnitz HM |
Load dependence of cardiac output in biventricular pacing: Right ventricular pressure overload in pigs |
J. Thorac. Cardiovasc. Surg., Jun 2004; 127: 1713 - 1722 |
RV micromanometer |
pig |
Cardiopulmonary support and physiology |
| Suematsu Y, Marx GR, Triedman JK, Mihaljevic T, Mora BN, Takamoto S, del Nido PJ |
Three-dimensional echocardiography–guided atrial septectomy: An experimental study |
J. Thorac. Cardiovasc. Surg., Jul 2004; 128: 53 - 59 |
5F micromanometer-tipped catheter |
pig |
Surgery for congenital heart disease |
| Huang Y, Hunyor SN, Jiang L , Kawaguchi O, Shirota K, Ikeda Y, Yuasa T, Gallagher G, Zeng B, Zheng X |
Remodeling of the chronic severely failing ischemic sheep heart after coronary microembolization: functional, energetic, structural, and cellular responses |
Am J Physiol Heart Circ Physiol 286: H2141-H2150, 2004 |
5F Mikro-Tip Catheter |
sheep |
neurohormones; pressure-volume loops; contractile reserve and energy efficiency; collagen and its phenotypes; wall stress and caspases |
| Chen RL, Penny DJ, Greve G, Lab MJ |
Stretch-induced regional mechanoelectric dispersion and arrhythmia in the right ventricle of anesthetized lambs |
Am J Physiol Heart Circ Physiol 286: H1008-H1014, 2004 |
Mikro-Tip catheter |
sheep (lamb) |
mechanoelectric feedback; early afterdepolarizations |
| Wang S, Dusting GJ, May CN, Woodman OL |
3',4'-Dihydroxyflavonol reduces infarct size and injury associated with myocardial ischaemia and reperfusion in sheep |
British Journal of Pharmacology (2004) 142, 443–452 |
4F catheter-tipped manometer |
sheep |
Flavonoid, myocardial infarction, ischaemia, reperfusion, antioxidant, nitric oxide |
| Ashikaga H, Criscione JC, Omens JH, Covell JW, Ingels Jr NB |
Transmural left ventricular mechanics underlying torsional recoil during relaxation |
Am J Physiol Heart Circ Physiol 286: H640-H647, 2004 |
8F Mikro-Tip catheter |
dog |
restoring force; transmural deformation; fiber; sheet |
| Rabinowitz JD, Wensley M, Lloyd P, Myers D, Shen W, Lu A, Hodges C, Hale R, Mufson D, Zaffaroni A |
Fast Onset Medications through Thermally Generated Aerosols |
JPET 309:769-775, 2004 |
MPC-500 |
dog |
Neuropharmacology |
| Wauthy P, Pagnamenta A, Vassalli F, Naeije R, Brimioulle S |
Right ventricular adaptation to pulmonary hypertension: an interspecies comparison |
Am J Physiol Heart Circ Physiol 286: H1441-H1447, 2004 |
SPC 350 |
dog, goat, pig |
heart failure; contractility; ventricular-arterial coupling |
| Skyschally A, Haude M, Dörge H, Thielmann M, Duschin A, van de Sand A, Konietzka I, Büchert A, Aker S, Massoudy P, Schulz R, Erbel R, Heusch G |
Glucocorticoid Treatment Prevents Progressive Myocardial Dysfunction Resulting From Experimental Coronary Microembolization |
Circulation. 2004;109:2337-2342 |
SPC-350 |
dog |
microcirculation • inflammation • ischemia • myocardial contraction |
| Belenkie I, Sas R, Mitchell J, Smith ER, Tyberg JV |
Opening the pericardium during pulmonary artery constriction improves cardiac function |
J Appl Physiol 96; 917-922, 2004 |
SPC-485A |
dog |
acute pulmonary hypertension; ventricular interaction |
| Sun Y-H, Anderson TJ, Parker KH, Tyberg JV |
Effects of left ventricular contractility and coronary vascular resistance on coronary dynamics |
Am J Physiol Heart Circ Physiol 286: H1590-H1595, 2004 |
SPC-485A |
dog |
wave intensity analysis; coronary flow impediment |
| Schenk S,Popovi B, Ochiai Y, Casas F, McCarthy PM, Starling RC, Kopcak Jr MW, Dessoffy R, Navia JL, Greenberg NL, Thomas JD, Fukamachi K |
Preload-adjusted right ventricular maximal power: concept and validation |
Am J Physiol Heart Circ Physiol 287: H1632-H1640, 2004 |
SPC-751, SPC-350, SPC-562-1 |
dog |
hemodynamics; contractility; right ventricle |
| Hamilton DR, Sas R, Tyberg JV |
Atrioventricular nonuniformity of pericardial constraint |
Am J Physiol Heart Circ Physiol 287: H1700-H1704, 2004 |
SPR279, SPR249 |
dog |
dogs; diastole physiology; systole physiology; pericardium physiology; ventricular function; ventricular pressure; atrial function; atrial pressure |
| Friedrich I, Börgermann J, Splittgerber FH, Brinkmann M, Reidemeister JC, Silber RE, Seeger W, Schmidt R, Günther A |
Bronchoscopic surfactant administration preserves gas exchange and pulmonary compliance after single lung transplantation in dogs |
J. Thorac. Cardiovasc. Surg., Feb 2004; 127: 335 - 343 |
pressure transducers |
dog |
Alveofact, leukocyte influx, vascular leakage, arterial oxygenation |
| Inoue M, McCarthy PM, Popovic ZB, Doi K, Schenk S, Nemeh H, Ootaki Y, Kopcak Jr MW, Dessoffy R, Thomas JD, Fukamachi K |
The Coapsys device to treat functional mitral regurgitation: In vivo long-term canine study |
J. Thorac. Cardiovasc. Surg., Apr 2004; 127: 1068 - 1077 |
Model SPC-562, model SPC-350 |
dog |
Cardiopulmonary support and physiology |
| Rasty S, Amin NB, Sabbah HN, Mishima T, Borzak S, Tisdale JE |
Influence of IV Haloperidol on Ventricular Repolarization and Monophasic Action Potential Duration in Anesthetized Dogs |
Chest, May 2004; 125: 1821 - 1829 |
catheter-tip micromanometer |
dog |
ventricular tachyarrhythmia torsades de pointes |
| Jacques DC, Pinsky MR, Severyn D, Gorcsan III J |
Influence of Alterations in Loading on Mitral Annular Velocity by Tissue Doppler Echocardiography and Its Associated Ability To Predict Filling Pressures |
Chest, Dec 2004; 126: 1910 - 1918 |
MPC-500 |
dog |
preload, afterload, and contractility |
| Bermejo J, Rojo-Álvarez JL, Antoranz JC, Abel M, Burwash IG, Yotti R, Moreno M, García-Fernández MA, Lehmann KG, Otto CM |
Estimation of the End of Ejection in Aortic Stenosis |
Circulation. 2004;110:1114-1120 |
high-fidelity, dual-micromanometer (5 cm apart) catheter |
dog |
valves • stenosis • catheterization • hemodynamics • animal experimentation |
| |
|
|
|
|
|
---------------------------------------------Published in 2003--------------------------------------------- |
Walcott GP, Melnick SB, Killingsworth CR, Smith WM, Ideker RE
|
Effects of burst stimulation during ventricular fibrillation on cardiac function after defibrillation
|
Am J Physiol Heart Circ Physiol 285: H766-H774, 2003
|
5F Mikro-Tip catheter |
pig |
ventricular fibrillation; timolol; ß-blockade
|
Stanley WC, Meadows SR, Kivilo KM,
Roth BA, Lopaschuk GD
|
"beta-Hydroxybutyrate inhibits myocardial fatty acid oxidation in vivo
independent of changes in malonyl-CoA content"
|
Am J Physiol Heart Circ Physiol 285: H1626-H1631, 2003
|
5-F Millar Mikro-tip transducer
|
pig |
lactate; metabolism, cardiac; heart; lactate
|
Pasipoularides A, Shu M, Shah A, Tucconi A, Glower DD
|
"RV instantaneous intraventricular diastolic pressure and velocity
distributions in normal and volume overload awake dog disease models"
|
Am J Physiol Heart Circ Physiol 285: H1956-H1965, 2003
|
Custom Mikro-Tip catheter |
pig |
echocardiography, sonomicrometry, computational fluid dynamics. intraventricular gradients; functional imaging; echocardiography; heart failure; ventricular function
|
Padilla F, Garcia-Dorado D, Rodríguez-Sinovas A,
Ruiz-Meana M, Inserte J,Soler-Soler J
|
"Protection afforded by ischemic preconditioning is not mediated by effects
on cell-to-cell electrical coupling during myocardial ischemia-reperfusion"
|
Am J Physiol Heart Circ Physiol 285: H1909-H1916, 2003
|
Mikro-Tip catheter |
pig |
myocardial ischemia; gap junctions
|
Niemann JT, Garner D, Khaleeli E, Lewis RJ
|
Milrinone Facilitates Resuscitation From Cardiac Arrest and Attenuates Postresuscitation Myocardial Dysfunction
|
Circulation. 2003;108:3031
|
Mikro-Tip catheter
|
pig
|
heart arrest • cardiopulmonary resuscitation • drugs • contractility
|
| Weidemann F, Dommke C, Bijnens B, Claus P, D'hooge J, Mertens P, Verbeken E, Maes A, Van de Werf F, De Scheerder I, Sutherland GR |
Defining the Transmurality of a Chronic Myocardial Infarction by Ultrasonic Strain-Rate Imaging Implications for Identifying Intramural Viability: An Experimental Study |
Circulation 2003 107:883-888 |
Millar catheter |
pig |
infarction • ultrasonics • contractility
|
| Pye J, Ardeshirpour F, McCain A, Bellinger DA, Merricks E, Adams J, Elliott PJ, Pien C, Fischer TH, Baldwin Jr AS, Nichols TC |
Proteasome inhibition ablates activation of NF-B in myocardial reperfusion and reduces reperfusion injury |
Am J Physiol Heart Circ Physiol 284: H919-H926, 2003 |
Millar catheter |
pig |
inflammation; myocardial contraction; multienzyme complexes; transcription factors
|
| Rondelet B, Kerbaul F, Motte S, van Beneden R, Remmelink M, Brimioulle S, McEntee K, Wauthy P, Salmon I, Ketelslegers J-M, Naeije R |
Bosentan for the Prevention of Overcirculation-Induced Experimental
Pulmonary Arterial Hypertension |
Circulation 2003 107:1329-1335 |
SPC- 350 |
pig |
endothelin • nitric oxide • growth substances • hypertension, pulmonary
|
Rodríguez-Sinovas A, JBis J, Anivarro I, de la Torre J, Bayés-Genís A, Cinca J
|
Coronary smooth muscle reactivity to muscarinic stimulation after ischemia-reperfusion in porcine myocardial infarction
|
J Appl Physiol 95: 81-88, 2003
|
SPC-350 |
pig |
arteries; receptors; methacholine; cholinergic agonists
|
Danton MHD, Greil GF, Byrne JG, Hsin M, Cohn L, Maier SE
|
"Right ventricular volume measurement by conductance catheter
magnetic resonance imaging; conductance catheter"
|
Am J Physiol Heart Circ Physiol 285: H1774-H1785, 2003
|
SPC-350 |
pig |
magnetic resonance imaging; conductance catheter
|
| Ayoub IM, Kolarova J, Yi Z, Trevedi A, Deshmukh , Lubell DL, Franz MR, Maldonado FA, Gazmuri RJ |
Sodium-Hydrogen Exchange Inhibition During Ventricular Fibrillation:
Beneficial Effects on Ischemic Contracture, Action Potential Duration,
Reperfusion Arrhythmias, Myocardial Function, and Resuscitability |
Circulation 2003 107:1804-1809 |
SPC-474A |
pig |
action potentials • cardiopulmonary resuscitation • defibrillation • ischemia • myocardium
|
Fadi Jamal, Cyrille Bergerot, Laurent Argaud, Joseph Loufouat, and Michel Ovize
|
Longitudinal strain quantitates regional right ventricular contractile function
|
Am J Physiol Heart Circ Physiol 285: H2842-H2847, 2003.
|
Two Mikro-Tip catheters
|
pig
|
myocardial contraction; regional myocardial function; cardiac mechanics; echocardiography; strain rate imaging
|
| Mekkaoui C, Rolland PH, Friggi A, Rasigni M, Mesana TG |
Pressure-flow loops and instantaneous input impedance in the thoracic aorta: Another way to assess the effect of aortic bypass graft implantation on myocardial, brain, and subdiaphragmatic perfusion |
J. Thorac. Cardiovasc. Surg., Mar 2003; 125: 699 - 710 |
SPR-249 |
pig |
ventriculoarterial coupling |
| Yarbrough WM, Mukherjee R, Brinsa TA, Dowdy KB, Scott AA, Escobar GP, Joffs C, Lucas DG, Crawford Jr FA, Spinale FG |
Matrix metalloproteinase inhibition modifies left ventricular remodeling after myocardial infarction in pigs |
J. Thorac. Cardiovasc. Surg., Mar 2003; 125: 602 - 610 |
7.5F |
pig |
infarct expansion |
| Lazar HL, Bao Y, Zhang Y, Bernard SA |
Pretreatment with statins enhances myocardial protection during coronary revascularization |
J. Thorac. Cardiovasc. Surg., May 2003; 125: 1037 - 1042 |
piezoelectric Mikro-Tip catheter pressure transducer |
pig |
ischemic injury |
| Martin J, Lutter G, Ihling C, Siepe M, Wagner S, Hilberath J, Kemper M, Sarai K, Beyersdorf F |
Myocardial viability twenty-four hours after orthotopic heart transplantation from non-heart-beating donors |
J. Thorac. Cardiovasc. Surg., Jun 2003; 125: 1217 - 1228 |
3F pressure-tip catheter |
pig |
donor hearts |
| Yarbrough WM, Mukherjee R, Escobar GP, Mingoia JT, Sample JA, Hendrick JW, Dowdy KB, McLean JE, Stroud RE, Spinale FG |
Direct inhibition of the sodium/hydrogen exchanger after prolonged regional ischemia improves contractility on reperfusion independent of myocardial viability |
J. Thorac. Cardiovasc. Surg., Nov 2003; 126: 1489 - 1497 |
Micro-Tip transducer 7.5 F |
pig |
myocardial dysfunction after ischemia and reperfusion |
| Castellá M, Buckberg GD, Saleh S, Tan Z, Ignarro LJ |
A new role for cardioplegic buffering: should acidosis or calcium accumulation be counteracted to salvage jeopardized hearts? |
J. Thorac. Cardiovasc. Surg., Nov 2003; 126: 1442 - 1448 |
MPC-500 |
pig |
ischemia-reperfusion injury |
| Maniar HS, Prasad SM, Gaynor SL, Chu CM, Steendijk P, Moon MR |
Impact of pericardial restraint on right atrial mechanics during acute right ventricular pressure load |
Am J Physiol Heart Circ Physiol 284: H350-H357, 2003 |
MPC-500 |
sheep |
atrial function; conductance catheter; pulmonary artery occlusion
|
| Jackson BM, Gorman III JH, Salgo IS, Moainie SL, Plappert T, St. John-Sutton M, Edmunds Jr LH, Gorman RC |
Border zone geometry increases wall stress after myocardial infarction: contrast echocardiographic assessment |
Am J Physiol Heart Circ Physiol 284: H475-H479, 2003 |
SPC-350 |
sheep |
congestive heart failure; remodeled myocardium; coronary artery disease; perfusion echocardiography
|
| Schröder HJ, Tchirikov M, Rybakowski C |
Pressure pulses and flow velocities in central veins of the anesthetized sheep fetus |
Am J Physiol Heart Circ Physiol 284: H1205-H1211, 2003 |
SPR-524 |
sheep |
fetal sheep; pressure wave; flow velocity; ductus venosus
|
| Kono S, Nishimura K, Nishina T, Yuasa S, Ueyama K, Hamada C, Akamatsu T, Komeda M |
Autosynchronized systolic unloading during left ventricular assist with a centrifugal pump |
J. Thorac. Cardiovasc. Surg., Feb 2003; 125: 353 - 360 |
SPC-500 |
sheep |
heart failure |
| Malhotra SP, Thelitz S, Riemer RK, Reddy VM, Suleman S, Hanley FL |
Induced fibrillation is equally effective as crystalloid cardioplegia in the protection of fetal myocardial function |
J. Thorac. Cardiovasc. Surg., Jun 2003; 125: 1276 - 1282 |
High-fidelity transducer-tipped catheters |
sheep |
congenital heart defects |
| Pilla JJ, Blom AS, Brockman DJ, Ferrari VA, Yuan Q, Acker MA |
Passive ventricular constraint to improve left ventricular function and mechanics in an ovine model of heart failure secondary to acute myocardial infarction |
J. Thorac. Cardiovasc. Surg., Nov 2003; 126: 1467 - 1475 |
5F micromanometer-tipped |
sheep |
woven polyester jacket cardiac support device |
| Ginés F, Grignola JC |
COMPORTAMIENTO MECANICO DEL VENTRICULO DERECHO |
Colección Trabajos Distinguidos Serie Cardiología, Volumen 11, Numero 3, 2003 |
SPC-370, TC-510 |
sheep |
contractilidad, endotoxemia, dobutamina, hipertensión pulmonar, ventrículo derecho |
| Kohno M, Yano M, Kobayashi S, Doi M, Oda T, Tokuhisa T, Okuda S, Ohkusa T, Kohno M, Matsuzaki M |
A new cardioprotective agent, JTV519, improves defective channel gating of ryanodine receptor in heart failure |
Am J Physiol Heart Circ Physiol 284: H1035-H1042, 2003 |
5F micromanometer Chronically implanted |
dog |
Heart failure, pharmaceuticals, sarcoplasmic reticulum; ion channel; binding protein; excitation-contraction coupling
|
Suematsu Y, Takamoto S, Kaneko Y, Ohtsuka T, Takayama H, Kotsuka Y, Murakami A
|
Beating Atrial Septal Defect Closure Monitored by Epicardial Real-Time Three-Dimensional Echocardiography Without Cardiopulmonary Bypass
|
Circulation. 2003;107:785
|
5F Mikro-Tip catheter |
dog |
Echocardiography, heart septal defects, cardiopulmonary bypass • echocardiography • heart septal defects
|
Yano M, ,Kobayashi S, Kohno M, Doi M, Tokuhisa T, Okuda S, Suetsugu M, Hisaoka T, Obayashi M, Ohkusa T, Kohno M, Matsuzaki M
|
FKBP12.6-Mediated Stabilization of Calcium-Release Channel (Ryanodine Receptor) as a Novel Therapeutic Strategy Against Heart Failure
|
Circulation. 2003;107:477
|
5F Mikro-Tip catheter |
dog |
Heart failure, pharmaceuticals, sarcoplasmic reticulum, heart failure, calcium, ion channels, remodeling
|
| Suematsu Y, Takamoto S, Kaneko Y, Ohtsuka T, Takayama H, Kotsuka Y, Murakami A |
Beating Atrial Septal Defect Closure Monitored by Epicardial Real-Time
Three-Dimensional Echocardiography Without Cardiopulmonary Bypass |
Circulation 2003 107:785-790 |
5F micromanometer-tipped catheter |
dog |
Left Heart studies (atrium), cardiopulmonary bypass • echocardiography • heart septal defects
|
Liu J, Masurekar MR, Vatner DE, Jyothirmayi GN, Regan TJ, Vatner SF, Meggs LG, Malhotra A
|
Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart
|
Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart
|
7F Mikro-Tip catheter |
dog
|
diabetes mellitus; alloxan model; myocardium; ALT-711
|
| Wang J-J, O'Brien AB, Shrive NG,Parker KH, Tyberg JV |
Time-domain representation of ventricular-arterial coupling as a windkessel and wave system |
Am J Physiol Heart Circ Physiol 284: H1358-H1368, 2003 |
High-fidelity catheter-tip manometers |
dog |
Left heart studies, aortic pressure; aortic flow; compliance; left ventricular ejection; waves
|
| Brimioulle S, Wauthy P, Ewalenko P, Rondelet B, Vermeulen F, Kerbaul F, Naeije R |
Single-beat estimation of right ventricular end-systolic pressure-volume
relationship |
Am J Physiol Heart Circ Physiol 284: H1625-H1630, 2003 |
Micromanometer catheter |
dog |
contractility; preload; afterload; pulmonary hypertension; hypoxia
|
Hong T-T, Driscoll EM, White AJ, Sherigill A, Giboulot TA, Lucchesi BR
|
Glycoprotein IIb/IIIa Receptor Antagonist (2S)-2-[(2-Naphthyl-sulfonyl)amino]-3-{[2-({4-(4-piperidinyl)-2-[2-(4-piperidinyl)ethyl] butanoyl}amino)acetyl]amino}propanoic Acid Dihydrochloride (CRL42796), in Combination with Aspirin and/or Enoxaparin, Prevents Coronary Artery Rethrombosis after Successful Thrombolytic Treatment by Recombinant Tissue Plasminogen Activator
|
JPET 306:616-623, 2003
|
Mikro-Tip catheter |
dog |
Intravascular thrombosis, thrombolytic therapy, platelet aggregation
|
Zhao Z-Q, Corvera JS, Halkos ME, Kerendi F, Wang N-P, Guyton RA, Vinten-Johansen J
|
Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning
|
Am J Physiol Heart Circ Physiol 285: H579-H588, 2003
|
Mikro-Tip catheter |
dog |
infarct size; neutrophils
|
Spragg DD, Leclercq C, Loghmani M, Faris OP, Tunin RS, DiSilvestre D, MS; McVeigh ER, Tomaselli GF, Kass DA
|
Regional Alterations in Protein Expression in the Dyssynchronous Failing Heart
|
Circulation. 2003;108:929
|
Mikro-Tip catheter |
dog |
heart failure • pacing • molecular biology • sarcoplasmic reticulum
|
| Liang C, Yatani A, Himura Y, Kashiki M, Stevenski SY |
Desipramine attenuates loss of cardiac sympathetic neurotransmitters produced by congestive heart failure and NE infusion |
Am J Physiol Heart Circ Physiol 284: H1729-H1736, 2003 |
Millar catheter |
dog |
neuronal uptake activity; histofluorescence; tyrosine hydroxylase; neuropeptide Y; protein gene product 9.5
|
Faris OP, Evans FJ, Dick AJ, Raman VK, Ennis DB, Kass DA, McVeigh ER
|
"Endocardial versus epicardial electrical synchrony during LV free-wall
pacing"
|
Am J Physiol Heart Circ Physiol 285: H1864-H1870, 2003
|
SPC-350 |
dog |
Left heart studies, resynchronization; mapping; heart failure
|
Yamada H, Martin DO, Mowrey KA, Greenberg NL, Wallick DW
|
Effects of coupled pacing on cardiac performance during acute atrial tachycardia and fibrillation: an old therapy revisited for a new reason
|
Am J Physiol Heart Circ Physiol 285: H2630-H2638, 2003
|
SPC-370
|
dog
|
contractility; heart rate; sinus rhythm; nonpharmacological approach; ventricular rate of mechanical contractions
|
Yada T, Goto M, Hiramatsu O, Tachibana H, Toyota E, Nakamoto H, Ogasawara Y, Matsuda H, Arakawa K, Hayashi K, Suzuki H, Kajiya F
|
In vivo visualization of subendocardial arteriolar response in renovascular hypertensive hearts
|
Am J Physiol Heart Circ Physiol 284: H1785-H1792, 2003
|
SPC-784A |
dog |
endothelium-dependent and -independent vasodilators; angiotensin-converting enzyme inhibitor
|
| Yada T, Shimokawa H, Hiramatsu O, Kajita T, Shigeto F, Goto M, Ogasawara Y, Kajiya F |
Hydrogen Peroxide, an Endogenous Endothelium-Derived Hyperpolarizing Factor, Plays an Important Role in Coronary Autoregulation In Vivo |
Circulation 2003 107:1040-1045 |
SPC-784A 8F pigtail double manometer catheter |
dog |
endothelium-derived factors • microcirculation • ischemia • nitric oxide • adenosine
|
Syuu Y, Matsubara H, Hosogi S, Suga H
|
Pressor effect of electroacupuncture on hemorrhagic hypotension
|
Am J Physiol Regul Integr Comp Physiol 285: R1446-R1452, 2003.
|
SPR-524
|
dog
|
Neiguan acupoints; left ventricular performance; vasomotor tone; cardiovascular response; muscle pump
|
| Muraki S, Morris CD, Budde JM, Zhao Z-Q, Guyton RA, Vinten-Johansen J |
Blood cardioplegia supplementation with the sodium-hydrogen ion exchange inhibitor cariporide to attenuate infarct size and coronary artery endothelial dysfunction after severe regional ischemia in a canine model |
J. Thorac. Cardiovasc. Surg., Jan 2003; 125: 155 - 164 |
MPC-500 |
dog |
sodium-calcium ion antiport mechanism |
| Kashem A, Hassan S, Crabbe DL, Melvin DB, Santamore WP |
Left ventricular reshaping: Effects on the pressure-volume relationship |
J. Thorac. Cardiovasc. Surg., Feb 2003; 125: 391 - 399 |
6F micromanometer-tipped pigtail catheter |
dog |
CardioClasp, heart failure |
| Koyama T, Nishimura K, Soga Y, Unimonh O, Ueyama K, Komeda M |
Importance of preserving the apex and plication of the base in left ventricular volume reduction surgery |
J. Thorac. Cardiovasc. Surg., Mar 2003; 125: 669 - 677 |
disposable microtipped catheter |
dog |
left ventricular fiber continuity, heart failure |
| Szabó G, Buhmann V, Graf A, Melnitschuk S, Bährle S, Vahl CF, Hagl S |
Ventricular energetics after the Fontan operation: Contractility-afterload mismatch |
J. Thorac. Cardiovasc. Surg., May 2003; 125: 1061 - 1069 |
piezoelectric Mikro-Tip catheter pressure transducer |
dog |
myocardial contractility |
| Fischer UM, Cox Jr CS, Allen SJ, Stewart RH, Mehlhorn U, Laine GA |
The antioxidant N-acetylcysteine preserves myocardial function and diminishes oxidative stress after cardioplegic arrest |
J. Thorac. Cardiovasc. Surg., Nov 2003; 126: 1483 - 1488 |
micromanometer-tipped pressure transducer |
dog |
myocardial edema resolution |
| Cox Jr CS, Allen SJ, Sauer H, Laine GA |
Improved Myocardial Function Using a Na+/H+ Exchanger Inhibitor During Cardioplegic Arrest and Cardiopulmonary Bypass |
Chest, Jan 2003; 123: 187 - 194 |
micromanometer-tipped pressure transducer |
dog |
myocardial edema |
| |
|
|
|
|
|
| ---------------------------------------------Published in 2002--------------------------------------------- |
| Sepic J, Wee JO, Soltesz EG, Hsin MK, Cohn LH, Laurence RG, Aklog L |
Cardiac positioning using an apical suction device maintains beating heart hemodynamics |
The Heart Surgery Forum #2002-01910 5(3):279-284, 2002 |
5F pressure transducing catheters |
pig, swine |
coronary bypass, deep pericardial sutures, hemodynamics
|
Weidemann F, Jamal F, Sutherland GR, Claus P, Kowalski M, Hatle L, De Scheerder I, Bijnens B, Rademakers FE
|
Myocardial function defined by strain rate and strain during alterations in inotropic states and heart rate
|
Am J Physiol Heart Circ Physiol 283: H792-H799, 2002
|
Mikro-Tip catheter
|
pig, swine
|
myocardial contraction; contractility; echocardiography
|
Luisi Jr AJ, Fallavollita JA, Suzuki G, Canty Jr JM
|
Spatial Inhomogeneity of Sympathetic Nerve Function in Hibernating Myocardium
|
Circulation. 2002;106:779
|
Mikro-Tip catheter 5F
|
pig, swine
|
hibernation • myocardial stunning • nervous system, sympathetic • death, sudden • ischemia
|
Sigg DC, Coles Jr JA, Oeltgen PR, Iaizzo PA
|
Role of delta-opioid receptor agonists on infarct size reduction in swine
|
Am J Physiol Heart Circ Physiol 282: H1953-H1960, 2002; 10.1152/ajpheart.01045.2001
|
MPC-500
|
pig, swine |
cardioprotection; myocardial ischemia; regional myocardial function; arrhythmia; delta-opioid receptor
|
Mongan PD, Capacchione J, West S, Karaian J, Dubois D, Keneally R, Sharma P
|
Pyruvate improves redox status and decreases indicators of hepatic apoptosis during hemorrhagic shock in swine
|
Am J Physiol Heart Circ Physiol 283: H1634-H1644, 2002
|
MPC-500
|
pig, swine |
glutathione; redox state; caspases
|
Schwartz LM, Welch TS, Crago MS
|
Cardioprotection by multiple preconditioning cycles does not require mitochondrial KATP channels in pigs |
Am J Physiol Heart Circ Physiol 283: H1538-H1544, 2002
|
SPC-780C |
pig, swine |
heart; infarction; ischemia; 5-hydroxydecanoate; diazoxide; mitochondria; ischemic preconditioning
|
| Graham MR, Warrian RK, Girling LG, Doiron L, Lefevre GR, Cheang M, Mutch WAC |
Fractal or biologically variable delivery of cardioplegic solution prevents diastolic dysfunction after cardiopulmonary bypass |
J. Thorac. Cardiovasc. Surg., Jan 2002; 123: 63 - 71 |
Millar Mikro-tip 3F catheter |
pig |
myocardial protection, cardioplegia |
| Lutter G, Kuklinski D, Berg G, von Samson P, Martin J, Handke M, Uhrmeister P, Beyersdorf F |
Percutaneous aortic valve replacement: An experimental study. I. Studies on implantation |
J. Thorac. Cardiovasc. Surg., Apr 2002; 123: 768 - 776 |
5F Millar micromanometers |
pig |
minimally invasive aortic valve implantation |
Hung J, Luis Guerrero JL, Handschumacher MD, Supple G, BSullivan S, Levine RA
|
Reverse Ventricular Remodeling Reduces Ischemic Mitral Regurgitation
|
Circulation. 2002;106:2594
|
High-fidelity micro-manometer–tipped catheter
|
sheep |
ischemia • mitral valve • ventricles • regurgitation • echocardiography
|
Yashu Coe, Stephen J. Haleen, Kathleen M. Welch, You-An Liu and Flavio Coceani
|
The Endothelin A Receptor Antagonists PD 156707 (CI-1020) and PD 180988 (CI-1034) Reverse the Hypoxic Pulmonary Vasoconstriction in the Perinatal Lamb
|
JPET, Vol. 302, Issue 2, 672-680, August 2002
|
Mikro-Tip catheter |
lamb, (sheep) |
hypoxia
|
Pilla JJ, Blom AS, Brockman DJ, Bowen F, Yuan Q, Giammarco J, Ferrari VA, Gorman III JH, Gorman RC, Acker MA
|
Ventricular Constraint Using the Acorn Cardiac Support Device Reduces Myocardial Akinetic Area in an Ovine Model of Acute Infarction
|
Circulation. 2002;106:I-207
|
Mikro-Tip Catheter |
sheep |
ventricles • remodeling • myocardial infarction • magnetic resonance imaging
|
Moustakidis P, Maniar HS, Cupps BP, Absi T, Zheng J, Guccione JM, Sundt TM, Pasque MK
|
Altered Left Ventricular Geometry Changes the Border Zone Temporal Distribution of Stress in an Experimental Model of Left Ventricular Aneurysm: A Finite Element Model Study
|
Circulation. 2002;106:I-168
|
SPC-350 MR |
sheep |
ischemia • coronary disease • magnetic resonance imaging • mechanics • computers
|
| Lansac E, Lim KH, Shomura Y, Goetz WA, Lim HS, Rice NT, Saber H, Duran CMG |
Dynamic balance of the aortomitral junction |
J. Thorac. Cardiovasc. Surg., May 2002; 123: 911 - 918 |
model 510 |
sheep |
Mitral anulus deformation |
Wei C-C, Ferrario CM, Brosnihan KB, Farrell DM, Bradley WE, Jaffa AA, Dell'Italia LJ
|
Angiotensin Peptides Modulate Bradykinin Levels in the Interstitium of the Dog Heart in Vivo
|
JPET, Vol. 300, Issue 1, 324-329, January 2002
|
4F Mikro-Tip catheter |
dog |
interstitial fluid
|
Segers P, Leather HA, Verdonck P, Sun Y-Y, Wouters PF
|
Preload-adjusted maximal power of right ventricle: contribution of end-systolic P-V relation intercept
|
Am J Physiol Heart Circ Physiol 283: H1681-H1687, 2002
|
5-Fr microtipped pressure-transducer catheter, 5-Fr dual-field conductance catheter
|
dog |
contractility; hydraulic; pressure-volume
|
LaDisa Jr JF, Hettrick DA, Olson LE, Guler I, Gross ER, Kress TT, Kersten JR, Warltier DC, Pagel PS
|
Stent implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation
|
J Appl Physiol 93: 1939-1946, 2002
|
7F dual sensor Mikro-Tip catheter |
dog |
slotted-tube endovascular stents; coronary impedance; coronary artery disease
|
| Piech A, Massart PE, Dessy C, Feron O, Havaux X, Morel N, Vanoverschelde J-L, Donckier J, Balligand J-L |
Decreased Expression of Myocardial eNOS and Caveolin in Dogs with Hypertrophic Cardiomyopathy |
Am J Physiol Heart Circ Physiol 282: H219-H231, 2002 |
7-F Microtipped Millar Catheter |
dog |
cardiac hypertrophy; diastolic function; perinephritic hypertension; endothelial nitric oxide synthase
|
| Burattini R, Campbell KB |
Comparative Analysis of Aortic Impedance and Wave Reflection In Ferrets and Dogs |
Am J Physiol Heart Circ Physiol 282: H244-H255, 2002;
|
Catheter-tipped Pressure Transducers |
ferret, dog |
arterial pulse wave propagation; arterial effective reflection sites; arterial compliance; T-tube arterial model
|
Pasipoularides A, Shu M, Shah A, Silvestry, Glower DD
|
Right ventricular diastolic function in canine models of pressure overload, volume overload, and ischemia
|
Am J Physiol Heart Circ Physiol 283: H2140-H2150, 2002
|
Ccustom-designed right heart Millar catheter with two micromanometers that were 5 cm apart
|
dog |
diastole; dynamics; heart failure; myocardial compliance; right ventricle
|
| Watanabe T, Yamaki M,Yamauchi S, Minamihaba O, Miyashita T, Kubota I, Tomoike H |
Regional Prolongation of ARI and Altered Restitution Properties Cause Ventricular Arrhythmia in Heart Failure |
Am J Physiol Heart Circ Physiol 282: H212-H218, 2002 |
Micromanometer |
dog |
restitution hypothesis; simulation
|
Zhuang S, Zhang Y, Mowrey KA, Li J, Tabata T, Wallick DW, Popovi ZB, Grimm RA, Natale A, MD; Todor N. Mazgalev TN
|
Ventricular Rate Control by Selective Vagal Stimulation Is Superior to Rhythm Regularization by Atrioventricular Nodal Ablation and Pacing During Atrial Fibrillation |
Circulation. 2002;106:1853
|
Micromanometer catheters
|
dog |
fibrillation • atrioventricular node • vagus nerve • ablation • hemodynamics
|
Juichiro Shimizu, Koji Todaka, and Daniel Burkhoff
|
Load dependence of ventricular performance explained by model of calcium-myofilament interactions
|
Am J Physiol Heart Circ Physiol 282: H1081-H1091, 2002; 10.1152/ajpheart.00498.2001
|
Micromanometer-tipped Catheter Pressue Transducer
|
dog |
left ventricle; calcium transient; four-state model; excitation-contraction coupling
|
Zhang Y, Mowrey KA, Zhuang S, Wallick DW, Popovi ZB, Mazgalev TN
|
Optimal ventricular rate slowing during atrial fibrillation by feedback AV nodal-selective vagal stimulation
|
Am J Physiol Heart Circ Physiol 282: H1102-H1110, 2002
|
Micromanometer-tipped Catheter Pressue Transducer
|
dog |
heart rhythm; arrhythmia; hemodynamics; autonomic control; atrioventricular node
|
| Wei K, Le E, Jayaweera AR, Bin J-P, Goodman NC, Kaul S |
Detection of Noncritical Coronary Stenosis at Rest Without Recourse to Exercise or Pharmacological Stress |
Circulation. 2002;105:218 |
Micromanometer-tipped Pressure Catheters |
dog |
"stenosis • echocardiography • blood volume
"
|
Setty S, Tune JD, Downey HF
|
Nitric oxide modulates right ventricular flow and oxygen consumption during norepinephrine infusion
|
J Physiol Heart Circ Physiol 282: H696-H703, 2002 |
Mikro-Tip catheter |
dog |
right coronary circulation; right ventricular oxygen utilization efficiency; open-chest dogs; N-nitro-L-arginine methyl ester
|
Grover GJ, D'Alonzo AJ, Darbenzio RB, Parham CS, Hess TA, Bathala MS
|
Mitochondrial Selective KATP Opener (3R)-trans-4-((4-Chlorophenyl)-N-(1H-imidazol-2-ylmethyl)dimethyl-2H-1-benzopyran-6-carbonitril Monohydrochloride (BMS-191095): Cardioprotective, Hemodynamic, and Electrophysiological Effects |
JPET Vol. 303, Issue 1, 132-140, October 2002
|
Mikro-Tip catheter |
dog |
cardioprotection
|
Popovi ZB, Mowrey KA, Zhang Y, Zhuang S, Tabata T, Wallick DW, Grimm RA, Thomas JD, Mazgalev TN
|
Slow rate during AF improves ventricular performance by reducing sensitivity to cycle length irregularity
|
Am J Physiol Heart Circ Physiol 283: H2706-H2713, 2002
|
Mikro-Tip Catheter |
dog |
vagus; relaxation; hemodynamics; atrial fibrillation
|
Suzuki G, Morita H, Mishima T, Sharov VG, Todor A, Tanhehco EJ, Rudolph AE, McMahon EG, Goldstein S, Sabbah HN
|
Effects of Long-Term Monotherapy With Eplerenone, a Novel Aldosterone Blocker, on Progression of Left Ventricular Dysfunction and Remodeling in Dogs With Heart Failure
|
Circulation. 2002;106:2967
|
Mikro-Tip Catheter |
dog |
heart failure • hemodynamics • remodeling
|
| Wyman BT, Hunter WC, Prinzen FW, Faris OP, McVeigh ER |
Effects of single- and bi-ventricular Pacing on Temporal and Spatial Dynamics of Ventricular Contraction |
Am J Physiol Heart Circ Physiol 282: H372-H379, 2002 |
SPC-350MR |
dog |
magnetic resonance imaging; tagging; cardiac mechanics; conduction abnormalities; cardiac mapping
|
Liu L, Tockman B, Girouard S, Pastore J, Walcott G, KenKnight B, Spinelli J
|
Left ventricular resynchronization therapy in a canine model of left bundle branch block
|
Am J Physiol Heart Circ Physiol 282: H2238-H2244, 2002. First published January 24, 2002; 10.1152/ajpheart.00684.2001
|
SPC-780c
|
dog
|
paradoxical septal wall motion; electromechanical coordination
|
Micheletti R, Mattera GG, Rocchetti M, Schiavone A, Loi MF, Zaza A, Gagnol RJP, De Munari S, Melloni P, Carminati P, Bianchi G, Ferrari P
|
Pharmacological Profile of the Novel Inotropic Agent (E,Z)-3-((2-Aminoethoxy)imino)androstane-6,17-dione Hydrochloride (PST2744)
|
JPET, Vol. 303, Issue 2, 592-600, November 2002
|
SPR-407 |
dog, guinea pig |
isolated guinea pig myocytes, arrhythmia, digoxin
|
Liang C-S, Himura Y, Kashiki M, Stevens SY
|
Differential pre- and postsynaptic effects of desipramine on cardiac sympathetic nerve terminals in RHF
|
Am J Physiol Heart Circ Physiol 283: H1863-H1872, 2002
|
Transducer tipped catheter |
dog |
congestive heart failure; neuronal norepinephrine uptake; tyrosine hydroxylase; neuropeptide Y
|
| Muraki S, Morris CD, Budde JM, Otto RN, Zhao Z-Q, Puskas JD, Guyton RA, Vinten-Johansen J |
Preserved myocardial blood flow and oxygen supply-demand balance with active coronary perfusion during simulated off-pump coronary artery bypass grafting |
J. Thorac. Cardiovasc. Surg., Jan 2002; 123: 53 - 62 |
MPC-500,SPC-320 |
dog |
intraluminal shunts, graft anastomosis |
| Klima UP, Lee M-Y, Guerrero JL, LaRaia J, Levine RA, Vlahakes GJ |
Determinants of maximal right ventricular function: Role of septal shift |
J. Thorac. Cardiovasc. Surg., Jan 2002; 123: 72 - 80 |
micromanometer-tipped catheter |
dog |
right ventricular free wall, the left ventricle, and the interventricular septum |
| Cox Jr CS, Sauer H, Allen SJ, Buja LM, Laine GA |
Sodium/hydrogen-exchanger inhibition during cardioplegic arrest and cardiopulmonary bypass: An experimental study |
J. Thorac. Cardiovasc. Surg., May 2002; 123: 959 - 966 |
micromanometer-tipped pressure transducer |
dog |
preload recruitable stroke work, maximum rate of pressure rise (positive and negative), and left ventricular end-diastolic volume and pressure |
| Nicolosi AC, West G, Markley JG, Logan B, Olinger GN |
Gadolinium attenuates regional stunning in the canine heart in vivo |
J. Thorac. Cardiovasc. Surg., Jul 2002; 124: 57 - 62 |
micromanometer-tipped catheter |
dog |
stretch-induced contractile dysfunction |
| Pasipoularides AD, Shu M, Shah A, Glower DD |
Right ventricular diastolic relaxation in conscious dog models of pressure overload, volume overload, and ischemia |
J. Thorac. Cardiovasc. Surg., Nov 2002; 124: 964 - 972 |
custom RV catheter |
dog |
right ventricular dysfunction |
| Ahmet I, Sawa Y, Iwata K, Matsuda H |
Gene transfection of hepatocyte growth factor attenuates cardiac remodeling in the canine heart: A novel gene therapy for cardiomyopathy |
J. Thorac. Cardiovasc. Surg., Nov 2002; 124: 957 - 963 |
MPC-500 |
dog |
Hepatocyte growth factor |
| Funatsu T, Sawa Y, Ohtake S, Takahashi T, Matsumiya G, Matsuura N, Nakamura T, Matsuda H |
Therapeutic angiogenesis in the ischemic canine heart induced by myocardial injection of naked complementary DNA plasmid encoding hepatocyte growth factor |
J. Thorac. Cardiovasc. Surg., Dec 2002; 124: 1099 - 1105 |
8 Fr catheter tipped micromanometer |
dog |
angiogenesis |
| Castellá M, Buckberg GD, Tan Z, Ignarro LJ |
Myocyte and endothelial effects of preconditioning the jeopardized heart by inhibiting Na+/H+ exchange |
J. Thorac. Cardiovasc. Surg., Dec 2002; 124: 1113 - 1121 |
MPC-500 |
dog |
cariporide |
| |
|
|
|
|
|
---------------------------------------------Published in 2001---------------------------------------------
|
| Zhenhai Gao1 , Zhihe Li1 , Stephen P. Baker, Robert D. Lasley, Stephanie Meyer, Elfatih Elzein, Venkata Palle, Jeff A. Zablocki, Brent Blackburn and Luiz Belardinelli |
Novel Short-Acting A2A Adenosine Receptor Agonists for Coronary Vasodilation: Inverse Relationship between Affinity and Duration of Action of A2A Agonists
|
Journal of Pharmacology and Experimental Therapeutics, Vol. 298, Issue 1, 209-218, July 2001 |
5F high-fidelity pressure sensitive tip transducer |
rat, pig |
coronary vasodilators, myocardial imaging
|
Söderqvist E, Carlsson C, Brodin LÅ, Elmqvist H, Kronander H, Ericsson AB
|
Design of a single segment conductance catheter for measurement of left ventricular volume
|
23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, October 25-28, 2001
|
5F Mikro-Tip catheter |
pig |
Left ventricular volume, conductance catheter, segment
volume, pigs
|
| Robert D. Lasley, M. Salik Jahania, and Robert M. Mentzer Jr. |
Beneficial effects of adenosine A2a agonist CGS-21680 in infarcted and stunned porcine myocardium
|
AJP Heart Circ Physiol., Vol. 280, Issue 4, H1660-H1666, April 2001
|
5F Mikro-Tip Pressure Transducer |
pig, swine |
adenosine A2a receptor; myocardial stunning; preload recruitable stroke work; myocardial infarction
|
| Takuma Etoh, Cassandra Joffs, Anne M. Deschamps, Jennifer Davis, Kathryn Dowdy, Jennifer Hendrick, Simona Baicu, Rupak Mukherjee, Marlina Manhaini, and Francis G. Spinale |
Myocardial and interstitial matrix metalloproteinase activity after acute myocardial infarction in pigs |
AJP Heart Circ Physiol Vol. 281, Issue 3, H987-H994, September 2001 |
7.5-F Mikro-Tip Pressure Transducer |
pig, swine |
zymography; microdialysis; myocardial ischemia
|
| Ashish R. Panchal, Blandine Comte, Hazel Huang, Basil Dudar, Bridgette Roth, Margaret Chandler, Christine Des Rosiers, Henri Brunengraber, and William C. Stanley |
Acute hibernation decreases myocardial pyruvate carboxylation and citrate release |
AJP Heart Circ. Physiol., Vol. 281, Issue 4, H1613-H1620, October 2001 |
7F Mikro-Tip Pressure Transducer |
pig, swine |
cardiac; citric acid cycle; dehydrogenase; metabolism; ischemia
|
| Nash MP, Thornton JM, Sears CE, Varghese A, O'Neill M, Paterson DJ |
Ventricular activation during sympathetic imbalance and its computational reconstruction
|
J Appl Physiol 90: 287-298, 2001
|
Mikro-Tip catheter |
pig |
catecholamines; cardiac mapping; porcine heart; ventricular arrhythmia
|
| Carole Seguin; Yvan Devaux; Sandrine Grosjean, MD; El Medhy Siaghy, PhD; Pierre Mairose; Faiez Zannad, MD, PhD; Nicole de Talancé, MD, PhD; Dan Ungureanu-Longrois, MD, PhD;; Paul Michel Mertes, MD, PhD |
Evidence of Functional Myocardial Ischemia Associated With Myocardial Dysfunction in Brain-Dead Pigs |
Circulation. 2001;104:I-197 |
Mikro-Tip Pressure Transducer |
pig, swine |
adenosine • ischemia • nervous system, sympathetic • transplantation
|
| Berg RA, Sanders AB, Kern KB, Hilwig RW, Heidenreich JW, Porter ME, Ewy GA |
Adverse hemodynamic effectsof interrupting chest compressions for rescue breathing during cardiopulmonary resuscitation for ventricular fibrillation cardiac arrest |
Circulation 2001;104:2465 |
MPC-500 |
pig |
cardiopulmonary resuscitation • heart arrest • hemodynamics • fibrillation • ventilation
|
| P. Tozzi, D. Hayoz, C. Oedman, I. Mallabiabarrena, and L. K. Von Segesser |
Systolic axial artery length reduction: an overlooked phenomenon in vivo |
AJP Heart Circ Physiol 280(5):H2300-H2305 |
MPC-500 |
pig, swine |
compliance; vascular ultrasound; sonography; arterial wall
|
| Paul D. Mongan, John Capacchione, John L. Fontana, Shanda West, and Rolf Bünger |
Pyruvate improves cerebral metabolism during hemorrhagic shock
|
AJP Heat Circ Physiol., Vol. 281, Issue 2, H854-H864, August 2001 |
MPC-500 |
pig, swine |
microdialysis; glutamate; pyruvic acid
|
| Danton MH, Byrne JG, Flores KQ, Hsin M, Martin JS, Laurence RG, Cohn LH, Aklog L |
Modified Glenn connection for acutely ischemic right ventricular failure reverses secondary left ventricular dysfunction |
J. Thorac. Cardiovasc. Surg., Jul 2001; 122: 80 - 91 |
SPC-350 |
pig |
left ventricular contractility and relaxation |
| Joffs C, Walker CA, Hendrick JW, Fary DJ, Almany DK, Davis JN, Goldberg AT, Crawford Jr FA, Spinale FG |
Endothelin receptor subtype A blockade selectively reduces pulmonary pressure after cardiopulmonary bypass |
J. Thorac. Cardiovasc. Surg., Aug 2001; 122: 365 - 370 |
precalibrated microtipped transducer (7.5F) |
pig |
pulmonary vascular resistance |
| Rao V, Feindel CM, Cohen G, Borger MA, Boylen P, Ross HJ |
Is profound hypothermia required for storage of cardiac allografts? |
J. Thorac. Cardiovasc. Surg., Sep 2001; 122: 501 - 507 |
micromanometer catheter |
pig |
blood perfusion, aerobic myocardial metabolism |
| Emmanuel Messas, MD, MSc; J. Luis Guerrero, BS; Mark D. Handschumacher, BS; Chris Conrad, BS; Chi-Ming Chow, MD; Suzanne Sullivan, BS; Ajit P. Yoganathan, PhD; Robert A. Levine, MD |
Chordal Cutting: A New Therapeutic Approach for Ischemic Mitral Regurgitation |
Circulation. 2001;104:1958 |
left atrial (LA) and LV Millar catheters |
sheep |
mitral valve • regurgitation • remodeling • myocardial infarction • echocardiography
|
| Emmanuel Messas, MD, MSc; J. Luis Guerrero, BS; Mark D. Handschumacher, BS; Chi-Ming Chow, MD; Suzanne Sullivan, BS; Ehud Schwammenthal, MD, PhD; Robert A. Levine, MD |
Paradoxic Decrease in Ischemic Mitral Regurgitation With Papillary Muscle Dysfunction |
Circulation. 2001;104:1952 |
left atrial [LA] and LV Millar catheters |
sheep |
mitral valve • regurgitation • remodeling • myocardial infarction • echocardiography
|
| Sten Lyager Nielsen, MD, PhD; Tomasz A. Timek, MD; David T. Lai, FRACS; George T. Daughters, MS; David Liang, MD, PhD; J. Michael Hasenkam, MD; Neil B. Ingels, PhD; D. Craig Miller, MD |
Edge-to-Edge Mitral Repair |
Circulation. 2001;104:I-29 |
Mikro-Tip Pressure Transducer |
sheep |
mitral valve • valvuloplasty • coronary disease
|
| Jean-Claude Fauchère, Adrian M. Walker, Elizabeth M. Skuza, and Daniel A. Grant |
Right atrial pressure as measure of ventricular constraint in newborn lambs |
AJP Heart Circ Physiol., Vol. 280, Issue 6, H2740-H2745, June 2001
|
SPC--460 |
lamb |
airway pressure; mechanical ventilation; pericardial pressure; positive end-expiratory pressure
|
Masanori Sasaki, DVM, Toyomi Takahashi, DVM, PhD, Kazuro Miyahara, DVM, PhD,
and Tsuneo Hirose, DVM, PhD |
Effects of Chondroitinase ABC on Intradiscal Pressure
in Sheep |
SPINE Volume 26, Number 5, pp 463–468 |
SPR-407 |
sheep |
chemonucleoysis, roentgenograph, disc height index
|
| Haft JW, Montoya P, Alnajjar O, Posner SR, Bull JL, Iannettoni MD, Bartlett RH, Hirschl RB |
An artificial lung reduces pulmonary impedance and improves right ventricular efficiency in pulmonary hypertension |
J. Thorac. Cardiovasc. Surg., Dec 2001; 122: 1094 - 1100 |
side-mounted pressure-sensing micromanometer |
sheep |
mean pulmonary artery pressure, zero harmonic impedance, right ventricular power consumption, amplitude of reflected waves, and the tension-time index |
| Diane M. Farrell, Chih-Chang Wei, José Tallaj, Jeffrey L. Ardell, J. Andrew Armour, Gilbert R. Hageman, Wayne E. Bradley, and Louis J. Dell'Italia |
Angiotensin II modulates catecholamine release into interstitial fluid of canine myocardium in vivo |
AJP Heart Circ Physiol., Vol. 281, Issue 2, H813-H822, August 2001
|
5F Mikro-Tip Pressure Transducer |
dog |
norepinephrine; epinephrine
|
| Christine L. Oltman, Neal L. Kane, Jonathon L. Fudge, Neal L. Weintraub, and Kevin C. Dellsperger |
Endothelium-derived hyperpolarizing factor in coronary microcirculation: responses to arachidonic acid |
AJP Heart Circ. Physiol., Vol. 281, Issue 4, H1553-H1560, October 2001
|
5F Mikro-Tip Pressure Transducer |
dog |
coronary circulation; coronary microcirculation; intravital microscopy
|
Masanori Shirakabe, Seiji Yamaguchi, Yoshiaki Tamada, Gajendra Baniya, Akio Fukui, Hiroshi Miyawaki, and Hitonobu Tomoike
|
Impaired distensibility of the left ventricle after stiffening of the right ventricle
|
J Appl Physiol 91: 435-440, 2001
|
6F Mikro-Tip catheter |
dog |
ventricular interdependence; ventricular geometry; left ventricular stiffness; diastolic function; length-tension relation
|
Charles T. Leng, MD; Ronald D. Berger, MD, PhD; Hugh Calkins, MD; Albert C. Lardo, PhD; Norman A. Paradis, MD; Henry R. Halperin, MD, MA
|
Electrical Induction of Ventricular Fibrillation for Resuscitation From Postcountershock Pulseless and Asystolic Cardiac Arrests |
Circulation. 2001;104:723 |
7F Millar micromanometer catheters |
dog |
fibrillation • cardiopulmonary resuscitation • myocardial stunning
|
| Masafumi Yano, Michihiro Kohno, Shigeki Kobayashi, Masakazu Obayashi, Kohzaburo Seki, Tomoko Ohkusa, Toshiro Miura, Takashi Fujii, and Masunori Matsuzaki |
Influence of timing and magnitude of arterial wave reflection on left ventricular relaxation
|
AJP Heart Circ Physiol., Vol. 280, Issue 4, H1846-H1852, April 2001
|
7F multi-sensor catheter |
human, dog |
coronary flow; ventricular function; afterload
|
| Gwyneth deVries, Douglas R. Hamilton, Henk E. D. J. Ter Keurs, Rafael Beyar, and John V. Tyberg |
A novel technique for measurement of pericardial pressure
|
AJP Heart Circ Physiol., Vol. 280, Issue 6, H2815-H2822, June 2001
|
8F Mikro-Tip Pressure Transducer with reference lumens |
dog |
pericardium; mechanics; balloon; catheters; physiology
|
| Sheng-Jing Dong, Paul S. Hees, Cynthia O. Siu, James L. Weiss, and Edward P. Shapiro |
MRI assessment of LV relaxation by untwisting rate: a new isovolumic phase measure of
|
AJP Heart Circ Physiol Vol. 281, Issue 5, H2002-H2009, November 2001
|
magnetic-compatible micromanometer-tipped catheter |
dog |
diastole; hemodynamics; magnetic resonance imaging; imaging
|
| Suehiro K, Shimizu J, Yi G-H, Gu A, Wang J, Keren G, Burkhoff D |
Selective Renal Vasodilation and Active Renal Artery Perfusion Improve Renal Function in Dogs with Acute Heart Failure
|
JPET, Vol. 298, Issue 3, 1154-1160, September 2001
|
Mikro-Tip catheter |
dog |
renal failure, blood pressure, papaverine
|
| S. De Mey, J. D. Thomas, N. L. Greenberg, P. M. Vandervoort, and P. R. Verdonck |
Assessment of the time constant of relaxation: insights from simulations and hemodynamic measurements |
AJP Heart Circ Physiol 280(6):H2936-H2943 |
Mikro-Tip Pressure Transducer |
dog |
hemodynamics; left ventricular relaxation constant; simulation
|
| Srinath Setty, Xiaoming Bian, Johnathan D. Tune, and H. Fred Downey |
Endogenous nitric oxide modulates myocardial oxygen consumption in canine right ventricle |
AJP Heart Circ Physiol., Vol. 281, Issue 2, H831-H837, August 2001
|
Mikro-Tip Pressure Transducer |
dog |
open-chest dogs; N-nitro-L-arginine methyl ester; maximal vasodilation; right coronary perfusion pressure; right coronary blood flow
|
| Daniel A. Velez, MD; Cullen D. Morris, MD; Jason M. Budde, MD; Satoshi Muraki, MD, PhD; Rachel N. Otto, BS; Robert A. Guyton, MD; Jakob Vinten-Johansen, PhD |
All-Blood (Miniplegia) Versus Dilute Cardioplegia in Experimental Surgical Revascularization of Evolving Infarction |
Circulation. 2001;104:I-296 |
Mikro-Tip Pressure Transducer |
dog |
cardioplegia • endothelium • infarction • surgery • edema
|
| George J. Crystal, Xiping Zhou, Syed Alam, Agnieszka Piotrowski, and Guochang Hu |
Lack of role for nitric oxide in cholinergic modulation of myocardial contractility in vivo |
AJP Heart Circ Physiol 281(1):H198-H206 |
Mikro-Tip Pressure Transducer |
dog |
coronary circulation; endothelium; bradykinin; sodium nitroprusside; amrinone; NG-nitro-L-arginine methyl ester; canine hearts
|
| Tomotsugu Tabata, Richard A. Grimm, Neil L. Greenberg, Deborah A. Agler, Kent A. Mowrey, Don W. Wallick, Youhua Zhang, Shaowei Zhuang, Todor N. Mazgalev, and James D. Thomas |
Assessment of LV systolic function in atrial fibrillation using an index of preceding cardiac cycles |
Ajp Heart Circ Physiol., Vol. 281, Issue 2, H573-H580, August 2001
|
Mikro-Tip Pressure Transducer |
dog |
preload; afterload; contractility; R-R interval; echocardiography; left ventricular
|
| Dewan S. A. Majid, Karim E. Said, Sophia A. Omoro, L. Gabriel Navar |
Nitric Oxide Dependency of Arterial Pressure–Induced Changes in Renal Interstitial Hydrostatic Pressure in Dogs |
Circulation Research. 2001;88:347 |
Mikro-Tip Pressure Transducer |
dog |
renal regional blood flow • laser-Doppler flowmetry • nitrate/nitrite excretion
|
| Don W. Wallick, Youhua Zhang, Tomotsugu Tabata, Shaowei Zhuang, Kent A. Mowrey, Junko Watanabe, Neil L. Greenberg, Richard A. Grimm, and Todor N. Mazgalev |
Selective AV nodal vagal stimulation improves hemodynamics during acute atrial fibrillation in dogs |
AJP Heart Circ Physiol., Vol. 281, Issue 4, H1490-H1497, October 2001
|
Mikro-Tip Pressure Transducer |
dog |
ventricular rate; epicardial fat pads; localized nerve stimulation
|
| Gary J. Grover, Albert J. D'Alonzo, Keith D. Garlid, Robert Bajgar, Nicholas J. Lodge, Paul G. Sleph, Raymond B. Darbenzio, Thomas A. Hess, Mark A. Smith, Petr Paucek and Karnail S. Atwal |
Pharmacologic Characterization of BMS-191095, a Mitochondrial KATP Opener with No Peripheral Vasodilator or Cardiac Action Potential Shortening Activity
|
Journal of Pharmacology and Experimental Therapeutics, Vol. 297, Issue 3, 1184-1192, June 2001 |
Mikro-Tip Pressure Transducer |
rat, guinea pig, dog |
glyburide-reversible cardioprotective activity, cromakalim, ischemia, reperfusion
|
| Yoshihisa Tanoue, MD; Akira Sese, MD; Yasutaka Ueno, MD; Kunitaka Joh, MD; Takayuki Hijii, MD |
Bidirectional Glenn Procedure Improves the Mechanical Efficiency of a Total Cavopulmonary Connection in High-Risk Fontan Candidates |
Circulation. 2001;103:2176 |
MPC-500 |
dog |
Glenn • mechanics • cavopulmonary • Fontan
|
| Denault AY, Gorcsan III J, Pinsky MR |
Dynamic effects of positive-pressure ventilation on canine left ventricular pressure-volume relations
|
J Appl Physiol 91: 298-308, 2001;
|
MPC-500 |
dog |
afterload; canine model; heart-lung interactions; mechanical ventilation; preload; ventricular function
|
| Neil L. Greenberg, Pieter M. Vandervoort, Michael S. Firstenberg, Mario J. Garcia, and James D. Thomas |
Estimation of diastolic intraventricular pressure gradients by Doppler M-mode echocardiography |
AJP Heart Circ Physiol 280(6):H2507-H2515 |
Single- and dual-sensor micromanometer catheters |
dog |
diastole; hemodynamics; ventricles
|
Nazareno Paolocci, MD, PhD; Pasquale Pagliaro, MD, PhD; Takayoshi Isoda, MD; Federico W. Saavedra, MD; David A. Kass, MD
|
Role of Calcium-Sensitive K+ Channels and Nitric Oxide in In Vivo Coronary Vasodilation From Enhanced Perfusion Pulsatility |
Circulation. 2001;103:119 |
SPC 350 |
dog |
circulation • ion channels • nitric oxide • bradykinin • endothelium-derived factors
|
| Kenichi Arimura, Kensuke Egashira, Ryo Nakamura, Tomomi Ide, Hiroyuki Tsutsui, Hiroaki Shimokawa, and Akira Takeshita |
Increased inactivation of nitric oxide is involved in coronary endothelial dysfunction in heart failure |
AJP Heart Circ Physiol., Vol. 280, Issue 1, H68-H75, January 2001 |
SPC-350 |
dog |
endothelium-derived factors; free radicals
|
Senzaki H, Smith CJ, Juang GJ, Isoda T, Mayer SP, Ohler A, Paolocci N, Tomaselli GF, Hare JM, Kass DA
|
Cardiac phosphodiesterase 5 (cGMP-specific) modulates ß-adrenergic signaling in vivo and is down-regulated in heart failure
|
The FASEB Journal. 2001;15:1718-1726
|
SPC-350 |
dog |
tissue activity • protein expression • coronary blood flow • PDE5
|
| Nakayama Y, Miyano H, Shishido T, Inagaki M, Kawada T, Sugimachi M, Sunagawa K |
Heart rate-dependent vagal effect on end-systolic elastance of the canine left ventricle under various levels of sympathetic tone |
Circulation 2001;104:2277 |
SPC-350 |
dog |
vagus nerve • nervous system, sympathetic • contractility • inotropism
|
Cholley BP, Lang RM, Korcarz CE, Shroff SG
|
Smooth muscle relaxation and local hydraulic impedance properties of the aorta
|
J Appl Physiol 90: 2427-2438, 2001
|
SPC-360 |
dog |
compliance; incremental elastic modulus; characteristic impedance; pulse wave velocity; calcium channel blocker
|
| Bruce B. Lerman, MD; Erica D. Engelstein, MD; Daniel Burkhoff, MD |
Mechanoelectrical Feedback |
Circulation. 2001;104:486 |
SPC-380 |
dog |
arrhythmias • electrophysiology• tachyarrhythmias • tachycardia
|
| Ellen H. Hollander, Jiun-Jr Wang, Gary M. Dobson, Kim H. Parker, and John V. Tyberg |
Negative wave reflections in pulmonary arteries |
AJP Heart Circ Physiol., Vol. 281, Issue 2, H895-H902, August 2001
|
SPC-480 |
dog |
lung; hemodynamics; PEEP
|
| Gregory S. Nelson, Ezzeldin Y. Sayed-Ahmed, Carol A. Gibbons Kroeker1, Yi-Hui Sun, Henk E. D. J. Ter Keurs, Nigel G. Shrive, and John V. Tyberg |
Compression of interventricular septum during right ventricular pressure loading |
AJP Heart Circ Physiol., Vol. 280, Issue 6, H2639-H2648, June 2001 |
SPC-485 |
dog |
finite element analysis; interventricular septum; mechanics; compressive stress
|
| D. Merkus, I. Vergroesen, O. Hiramatsu, H. Tachibana, H. Nakamoto, E. Toyota, M. Goto, Y. Ogasawara, J. A. E. Spaan, and F. Kajiya |
Stenosis differentially affects subendocardial and subepicardial arterioles in vivo
|
AJP Heart Circ Physiol., Vol. 280, Issue 4, H1674-H1682, April 2001
|
SPC-784A |
dog |
autoregulation; coronary microcirculation; ischemia
|
| Akira Ido, Naoyuki Hasebe, Hironobu Matsuhashi, and Kenjiro Kikuchi |
Coronary sinus occlusion enhances coronary collateral flow and reduces subendocardial ischemia |
AJP Heart Circ Physiol., Vol. 280, Issue 3, H1361-H1367, March 2001
|
SPR-230 |
dog |
intramyocardial pressure; regional myocardial blood flow; coronary collateral blood flow; anesthetized dog
|
Hamilton DR, Devries G, Tyberg JV
|
Static and dynamic operating characteristics of a pericardial balloon
|
J Appl Physiol 90: 1481-1488, 2001
|
SPR-249 |
dog |
pericardium; pericardial pressure; transducer; frequency response; epicardial stress
|
| Johnathan D. Tune, Keith Neu Richmond, Mark W. Gorman, and Eric O. Feigl |
KATP+ channels, nitric oxide, and adenosine are not required for local metabolic coronary vasodilation |
AJP Heart Circ Physiol., Vol. 280, Issue 2, H868-H875, February 2001 |
SPR-524 |
dog |
coronary blood flow; exercise; myocardial oxygen consumption
|
| Karunanithi MK, Michniewicz J, Young JA,Feneley MP |
Effect of acutely increased left ventricular afterload on work output from the right ventricle in conscious dogs |
J. Thorac. Cardiovasc. Surg., Jan 2001; 121: 116 - 124 |
MPC-500 |
dog |
right ventricular free wall segment work output |
| MurakiS, Morris CD, Budde JM, Velez DA, Zhao Z-Q, Guyton RA, Vinten-Johansen J |
Experimental off-pump coronary artery revascularization with adenosine-enhanced reperfusion |
J. Thorac. Cardiovasc. Surg., Mar 2001; 121: 570 - 579 |
MPC-500, SPC-320 |
dog |
perfusion-assisted direct coronary artery bypass |
| Suematsu Y, Takamoto S, Ohtsuka T |
Intraoperative echocardiographic imaging of coronary arteries and graft anastomoses during coronary artery bypass grafting without cardiopulmonary bypass |
J. Thorac. Cardiovasc. Surg., Dec 2001; 122: 1147 - 1154 |
5F micromanometer-tipped catheter |
dog, human |
high-frequency epicardial echocardiography and power Doppler imaging |
| |
|
|
|
|
|
---------------------------------------------Published in 2000---------------------------------------------
|
| Paul J. Chai, MD; Rashid Nassar, PhD; Annette E. Oakeley; Damian M. Craig, MS; George Quick, Jr; James Jaggers, MD; Stephen P. Sanders, MD; Ross M. Ungerleider, MD; Page A. W. Anderson, MD |
Soluble Complement Receptor-1 Protects Heart, Lung, and Cardiac Myofilament Function From Cardiopulmonary Bypass Damage |
Circulation. 2000;101:541 |
3F Mikro-Tip catheter |
pig, swine |
|
| Hermann H. Klein, MD; Sibylle Pich, PhD; Rainer M. Bohle, MD; Stephanie Lindert-Heimberg; Klaus Nebendahl, VMD |
Na+/H+ Exchange Inhibitor Cariporide Attenuates Cell Injury Predominantly During Ischemia and Not at Onset of Reperfusion in Porcine Hearts With Low Residual Blood Flow |
Circulation. 2000;102:1977 |
5F Mikro-Tip catheter |
pig, swine |
|
| Peili Zhu, Li Lu, Ya Xu, Clifford Greyson, and Gregory G. Schwartz |
Glucose-insulin-potassium preserves systolic and diastolic function in ischemia and reperfusion in pigs |
AJP Heart Circ Physiol., Vol. 278, Issue 2, H595-H603, February 2000
|
5F Mikro-Tip catheter |
pig, swine |
|
| Adviye Ergul, C. Allyson Walker, Aron Goldberg, Simona C. Baicu, Jennifer W. Hendrick, Mary K. King, and Francis G. Spinale |
ET-1 in the myocardial interstitium: relation to myocyte ECE activity and expression
|
AJP Heart Circ Physiol., Vol. 278, Issue 6, H2050-H2056, June 2000
|
7.5F Mikro-Tip catheter |
pig, swine |
|
| R. Brent New, MD; Angela C. Sampson, BS; Mary K. King, DVM; Jennifer W. Hendrick, BA; Mark J. Clair, MS; James H. McElmurray, III, BS; Jeffrey Mandel, MD; Rupak Mukherjee, PhD; Marc de Gasparo, MD; Francis G. Spinale, MD, PhD |
Effects of Combined Angiotensin II and Endothelin Receptor Blockade With Developing Heart Failure |
Circulation. 2000;102:1447 |
7.5F Mikro-Tip catheter |
pig, swine |
|
| Ashish R. Panchal, Blandine Comte, Hazel Huang, Todd Kerwin, Ahmed Darvish, Christine Des Rosiers, Henri Brunengrabe, and William C. Stanley |
Partitioning of pyruvate between oxidation and anaplerosis in swine hearts
|
AJP Heart Circ Physiol., Vol. 279, Issue 5, H2390-H2398, November 2000
|
7F Mikro-Tip catheter |
pig, swine |
|
| Clifford Greyson, Ya Xu, Li Lu, and Gregory G. Schwartz |
Right ventricular pressure and dilation during pressure overload determine dysfunction after pressure overload |
AJP Heart Circ Physiol 278(5):H1414-H1420 |
Mikro-Tip catheter |
pig, swine |
|
| Robert A. Berg, MD; Ronald W. Hilwig, DVM, PhD; Karl B. Kern, MD; Gordon A. Ewy, MD |
"Bystander" Chest Compressions and Assisted Ventilation Independently Improve Outcome From Piglet Asphyxial Pulseless "Cardiac Arrest" |
Circulation 2000;101:1743 |
Mikro-Tip catheter |
pig, swine |
|
| Ronald W. Hilwig, DVM, PhD; Robert A. Berg, MD; Karl B. Kern, MD; Gordon A. Ewy, MD |
Endothelin-1 Vasoconstriction During Swine Cardiopulmonary Resuscitation Improves Coronary Perfusion Pressures but Worsens Postresuscitation Outcome |
Circulation. 2000;101:2097 |
MPC-500 |
pig, swine |
|
Kleen M, Habler O, Meisner F, Kemming G, Pape A, Messmer K
|
Effects of primary resuscitation from shock on distribution of myocardial blood flow
|
J Appl Physiol 88: 373-385, 2000
|
SPC-370 |
pig, swine |
fractals; spatial heterogeneity; regional perfusion; coronary stenosis; hemoglobin-based oxygen carriers; albumin; pigs
|
| Harald Kjekshus, Cecilie Risoe, Tim Scholz, and Otto A. Smiseth |
Methods for assessing hepatic distending pressure and changes in hepatic capacitance in pigs |
AJP Heart Circ Physiol 279(4):H1796-H1803 |
SPR-407 |
pig, swine |
|
| Riley RD, Sato H, Zhao Z-Q, Thourani VH, Jordan JE, Fernandez AX, Ma X-L, MD, Hite DR, Rigel DF, Pellas TC, Peppard J, Bill KA, Lappe RW, Vinten-Johansen J |
Recombinant human complement C5a receptor antagonist reduces infarct size after surgical revascularization |
J Thorac Cardiovasc Surg 2000;120:350-358 |
MPC-500 |
pig |
coronary occlusion |
| Lau CL, Daggett WC, Yeatman MF, Chai P, Lin SS, Lodge AJ, Chen EP, Diamond LE, Byrne GW, PLogan JS, Parker W, Platt JL, Davis RD |
The role of antibodies in dysfunction of pig-to-baboon pulmonary transplants |
J Thorac Cardiovasc Surg 2000;120:29-38 |
Mikro-Tip micromanometer |
pig, baboon |
pulmonary xenotransplantation |
| Langley MS, Chai PJ, Tsui SS, Jaggers JJ, Ungerleider RM |
THE EFFECTS OF A LEUKOCYTE-DEPLETING FILTER ON CEREBRAL AND RENAL RECOVERY AFTER DEEP HYPOTHERMIC CIRCULATORY ARREST |
J Thorac Cardiovasc Surg 2000;119:1262-1269 |
3F micromanometer |
pig |
cardiopulmonary bypass |
| Langley SM, Chai PJ, Jaggers JJ, Ungerleider RM |
THE FREE RADICAL SPIN TRAP -PHENYL-TERT-BUTYL NITRONE ATTENUATES THE CEREBRAL RESPONSE TO DEEP HYPOTHERMIC ISCHEMIA |
J Thorac Cardiovasc Surg 2000;119:305-313 |
3F micromanometer |
pig |
Reactive oxygen species, circulatory arrest |
| Walker CA, Baicu SC, Goldberg AT, Widener CE, Fary DJ, Almany DK, Ergul A, Crawford Jr FA, Spinale FG |
Temporal endothelin dynamics of the myocardial interstitium and systemic circulation in cardiopulmonary bypass |
J Thorac Cardiovasc Surg 2000;120:864-871 |
precalibrated microtipped transducer, 7.5F |
pig |
Myocardial interstitial endothelin 1 |
| Pearl MJ, Nelson DP, Wellmann SA, Raake JL, Wagner CJ, McNamara JL, Duffy JY |
Acute hypoxia and reoxygenation impairs exhaled nitric oxide release and pulmonary mechanics |
J Thorac Cardiovasc Surg 2000;119:931-938 |
Transducer-tipped catheters |
pig |
cardiopulmonary bypass |
| Yoshiya Toyoda, MD; Vincenzo Di Gregorio, MD; Robert A. Parker, ScD; Sidney Levitsky, MD; James D. McCully, PhD |
Anti-Stunning and Anti-Infarct Effects of Adenosine-Enhanced Ischemic Preconditioning |
Circulation 2000;102:III-326 |
Mikro-Tip catheter |
sheep |
|
| Lai DTM, Timek TA, Dagum P, Green GR, Glasson JR, Daughters GT, Liang D, Ingels Jr NB, Miller C |
The effects of ring annuloplasty on mitral leaflet geometry during acute left ventricular ischemia |
J Thorac Cardiovasc Surg 2000;120:966-975 |
MPC-500 |
sheep |
biplane videofluoroscopy |
| Schermerhorn ML, Tofukuji M, Khoury PR, Phillips L, Hickey PR, Sellke FW, Mayer Jr JE , Nelson DP |
Sialyl LewisX oligosaccharide preserves cardiopulmonary and endothelial function after hypothermic circulatory arrest in lambs |
J Thorac Cardiovasc Surg 2000;120:230-237 |
SPC-350 |
sheep |
Neutrophil adhesion |
| Nagashima M, Nollert G, Stock U, Sperling J, Hatsuoka S, Shum-Tim D, Takeuchi K, Nedder A, Mayer Jr JE |
Cardiac performance after deep hypothermic circulatory arrest in chronically cyanotic neonatal lambs |
J Thorac Cardiovasc Surg 2000;120:238-246 |
SPC-350 |
sheep |
alveolar hypoxic stress |
| Ratcliffe MB, Wallace AW, Teerlink JR, Hong J, Salahieh A, Sung S-H, Keung EC, Lee RJ |
RADIO FREQUENCY HEATING OF CHRONIC OVINE INFARCT LEADS TO SUSTAINED INFARCT AREA AND VENTRICULAR VOLUME REDUCTION |
J Thorac Cardiovasc Surg 2000;119:1194-1204 |
MPC-500 |
sheep |
left ventricular remodeling |
| Ratcliffe MB, Wallace AW, Salahieh A, Hong J, Ruch S, Hall TS |
VENTRICULAR VOLUME, CHAMBER STIFFNESS, AND FUNCTION AFTER ANTEROAPICAL ANEURYSM PLICATION IN THE SHEEP |
J Thorac Cardiovasc Surg 2000;119:115-124 |
SPC-320 |
sheep |
End-systolic elastance, diastolic compliance, PRSW, and Starling relationships |
Sun Y-H, Anderson TJ, Parker KH, Tyberg JV
|
Wave-intensity analysis: a new approach to coronary hemodynamics
|
J Appl Physiol 89: 1636-1644, 2000
|
2.5F Mikro-Tip catheter |
dog |
|
| Giorgio Sironi, Davide Colombo, Elena Poggesi, Amedeo Leonardi, Rodolfo Testa, Olivier Rampin1, Jacques Bernabé1 and Francois Giuliano2 |
Effects of Intracavernous Administration of Selective Antagonists of 1-Adrenoceptor Subtypes on Erection in Anesthetized Rats and Dogs
|
Journal of Pharmacology and Experimental Therapeutics, Vol. 292, Issue 3, 974-981, March 2000 |
6F Mikro-Tip catheter |
dog, rat |
|
| Yoshitatsu Nagatomo, Blase A. Carabello, Mytsi L. Coker, Paul J. McDermott, Shintaro Nemoto, Masayoshi Hamawaki, and Francis G. Spinale |
Differential effects of pressure or volume overload on myocardial MMP levels and inhibitory control |
AJP Heart Circ Physiol., Vol. 278, Issue 1, H151-H161, January 2000
|
7.5F Mikro-Tip catheter |
dog |
|
| Masafumi Yano, Michihiro Kohno, Tomoko Ohkusa, Mamoru Mochizuki, Jutaro Yamada, Masateru Kohno, Takayuki Hisaoka, Kaoru Ono, Taketo Tanigawa, Shigeki Kobayashi, and Masunori Matsuzaki |
Effect of milrinone on left ventricular relaxation and Ca2+ uptake function of cardiac sarcoplasmic reticulum |
AJP Heart Circ Physiol., Vol. 279, Issue 4, H1898-H1905, October 2000
|
7F Mikro-Tip catheter |
dog |
|
Masafumi Yano, MD, PhD; Kaoru Ono, MD; Tomoko Ohkusa, MD, PhD; Masae Suetsugu, BS; Masateru Kohno, MD; Takayuki Hisaoka, MD; Shigeki Kobayashi, MD, PhD; Yuji Hisamatsu, MD, PhD; Takeshi Yamamoto, MD, PhD; Michihiro Kohno, MD, PhD; Naoya Noguchi, MD, PhD; Shin Takasawa, MD, PhD; Hiroshi Okamoto, MD, PhD; Masunori Matsuzaki, MD, PhD
|
Altered Stoichiometry of FKBP12.6 Versus Ryanodine Receptor as a Cause of Abnormal Ca2+ Leak Through Ryanodine Receptor in Heart Failure |
Circulation. 2000;102:2131 |
7F Mikro-Tip catheter |
dog |
|
| Taketo Tanigawa, Masafumi Yano, Michihiro Kohno, Takeshi Yamamoto, Takayuki Hisaoka, Kaoru Ono, Takeshi Ueyama, Shigeki Kobayashi, Yuhji Hisamatsu, Tomoko Ohkusa, and Masunori Matsuzaki |
Mechanism of preserved positive lusitropy by cAMP-dependent drugs in heart failure |
AJP Heart Circ Physiol., Vol. 278, Issue 2, H313-H320, February 2000
|
7F Mikro-Tip catheter |
dog |
|
| Charles T. Leng, MD; Norman A. Paradis, MD; Hugh Calkins, MD; Ronald D. Berger, MD, PhD; Albert C. Lardo, PhD; Kenneth C. Rent; Henry R. Halperin, MD, MA |
Resuscitation After Prolonged Ventricular Fibrillation With Use of Monophasic and Biphasic Waveform Pulses for External Defibrillation |
Circulation. 2000;101:2968 |
7F Mikro-Tip catheter |
dog |
|
| Hani N. Sabbah, PhD; William C. Stanley, PhD; Victor G. Sharov, MD, PhD; Takayuki Mishima, MD; Mitsuhiro Tanimura, MD; Claude R. Benedict, MD; Sharath Hegde, PhD; Sidney Goldstein, MD |
Effects of Dopamine ß-Hydroxylase Inhibition With Nepicastat on the Progression of Left Ventricular Dysfunction and Remodeling in Dogs With Chronic Heart Failure |
Circulation 2000;102:1990 |
Mikro-Tip catheter |
dog |
|
| Vinod H. Thourani, Sukhdev S. Brar, Thomas P. Kennedy, Lisa R. Thornton, John A. Watts, Russell S. Ronson, Zhi-Qing Zhao, Anne L. Sturrock, John R. Hoidal, and Jakob Vinten-Johansen |
Nonanticoagulant heparin inhibits NF-kappaB activation and attenuates myocardial reperfusion injury |
AJP Heart Circ Physiol 278(6):H2084-H2093 |
Mikro-Tip catheter |
dog |
|
| Masayoshi Nagatsu, MD; Francis G. Spinale, MD, PhD; Masaaki Koide, MD; Hirofumi Tagawa, MD; Gilberto DeFreitas, BS; George Cooper, IV, MD; Blase A. Carabello, MD |
Bradycardia and the Role of ß-Blockade in the Amelioration of Left Ventricular Dysfunction |
Circulation. 2000;101:653 |
Mikro-Tip catheter |
dog |
|
| Kun Don Yi, H. Fred Downey, Xiaoming Bian, Min Fu, and Robert T. Mallet |
Dobutamine enhances both contractile function and energy reserves in hypoperfused canine right ventricle |
AJP Heart Circ Physiol 279(6):H2975-H2985 |
Mikro-Tip catheter |
dog |
|
| Leonarda Galiuto, MD; Anthony N. DeMaria, MD; Ughetta del Balzo, PhD; Karen May-Newman, PhD; Stephen F. Flaim, PhD; Paul L. Wolf, MD; Michael Kirchengast, PhD; Sabino Iliceto, MD |
Ischemia-Reperfusion Injury at the Microvascular Level |
Circulation 2000;102:3111 |
Mikro-Tip catheter |
dog |
|
Gérald Vanzetto, MD, PhD; David K. Glover, ME; Mirta Ruiz, MD; Dennis A. Calnon, MD; Roberto Pasqualini, PhD; Denny D. Watson, PhD; George A. Beller, MD
|
99mTc-N-NOET Myocardial Uptake Reflects Myocardial Blood Flow and Not Viability in Dogs With Reperfused Acute Myocardial Infarction |
Circulation. 2000;101:2424 |
Mikro-Tip catheter |
dog |
|
| Johnathan D. Tune, PhD; Keith Neu Richmond, PhD; Mark W. Gorman, PhD; Eric O. Feigl, MD |
Role of Nitric Oxide and Adenosine in Control of Coronary Blood Flow in Exercising Dogs |
Circulation 2000;101:2942 |
Mikro-Tip catheter |
dog |
|
| Charles V. Jackson, Blanche D. Bailey and Timothy J. Shetler |
Pharmacological Profile of Recombinant, Human Activated Protein C (LY203638) in a Canine Model of Coronary Artery Thrombosis |
Journal of Pharmacology and Experimental Therapeutics, Vol. 295, Issue 3, 967-971, December 2000 |
MPC-500 |
dog |
|
| Stig Urheim, MD; Thor Edvardsen, MD; Hans Torp, Dr techn; Bjørn Angelsen, Dr techn; Otto A. Smiseth, MD, PhD |
Myocardial Strain by Doppler Echocardiography |
Circulation. 2000;102:1158 |
MPC-500 |
dog |
|
| Masanori Nakamura, MD, PhD; Vinod H. Thourani, MD; Russell S. Ronson, MD; Daniel A. Velez, MD; Xin-Liang Ma, MD, PhD; Sara Katzmark, BS; Jill Robinson, BS; L. Susan Schmarkey, BS; Zhi-Qing Zhao, MD, PhD; Ning-Ping Wang, MD; Robert A. Guyton, MD; Jakob Vinten-Johansen, PhD |
Glutathione Reverses Endothelial Damage From Peroxynitrite, the Byproduct of Nitric Oxide Degradation, in Crystalloid Cardioplegia |
Circulation. 2000;102:III-332 |
MPC-500 |
dog |
|
| Hilmar Dörge, Till Neumann, Matthias Behrends, Andreas Skyschally, Rainer Schulz, Christoph Kasper, Raimund Erbel, and Gerd Heusch |
Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation |
AJP Heart Circ Physiol., Vol. 279, Issue 6, H2587-H2592, December 2000
|
SPC-350 |
dog |
|
| Jos A. E. Spaan, Annemiek J. M. Cornelissen, Charles Chan, Jenny Dankelman, and Frank C. P. Yin |
Dynamics of flow, resistance, and intramural vascular volume in canine coronary circulation
|
AJP Heart Circ Physiol., Vol. 278, Issue 2, H383-H403, February 2000
|
SPC-450 |
dog |
|
Toshiaki Shishido, MD, PhD; Kazuko Hayashi, MD; Kenji Shigemi, MD, PhD; Takayuki Sato, MD, PhD; Masaru Sugimachi, MD, PhD; Kenji Sunagawa, MD, PhD
|
Single-Beat Estimation of End-Systolic Elastance Using Bilinearly Approximated Time-Varying Elastance Curve |
Circulation. 2000;102:19 |
SPC-751 |
dog |
|
| Judy R. Kersten, Wolfgang G. Toller, Eric R. Gross, Paul S. Pagel, and David C. Warltier |
Diabetes abolishes ischemic preconditioning: role of glucose, insulin, and osmolality
|
AJP Heart Circ Physiol., Vol. 278, Issue 4, H1218-H1224, April 2000
|
SPC-771 |
dog |
|
| Johnathan D. Tune, Keith Neu Richmond, Mark W. Gorman, Ray A. Olsson, and Eric O. Feigl |
Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise |
AJP Heart Circ Physiol., Vol. 278, Issue 1, H74-H84, January 2000 |
SPR-524 |
dog |
|
Gorman MW, Tune JD, Richmond KN, Feigl EO
|
Feedforward sympathetic coronary vasodilation in exercising dogs
|
J Appl Physiol 89: 1892-1902, 2000
|
SPR-524 |
dog |
|
Richmond KN, Tune JD, Gorman MW, Feigl EO
|
Role of KATP+ channels and adenosine in the control of coronary blood flow during exercise
|
J Appl Physiol 89: 529-536, 2000
|
SPR-524 |
dog |
|
| Artrip JH, Yi G-H, Shimizo J, Feihn E, Sciacca RR, Wang J, Burkhoff D |
Maximizing hemodynamic effectiveness of biventricular assistance by direct cardiac compression studied in ex vivo and in vivo canine models of acute heart failure |
J Thorac Cardiovasc Surg 2000;120:379-386 |
solid-state MikroTip catheter |
dog |
contractility |
| Shah AS, Atkins BZ, Hata JA, Tai O, Kypson AP, Lilly RE, Koch WJ, Glower DD |
Early effects of right ventricular volume overload on ventricular performance and ß-adrenergic signaling |
J Thorac Cardiovasc Surg 2000;120:342-349 |
5F micromanometer |
dog |
tricuspid regurgitation |
| Karunanithi MK, Feneley MP |
Limitations of unidimensional indexes of right ventricular contractile function in conscious dogs |
J Thorac Cardiovasc Surg 2000;120:302-312 |
MPC-500 |
dog |
Vena caval occlusions |
| Atkins BZ, Silvestry SC, Samy RN, Shah AS, Sabiston Jr DC , Glower DD |
CALCITONIN GENE–RELATED PEPTIDE ENHANCES THE RECOVERY OF CONTRACTILE FUNCTION IN STUNNED MYOCARDIUM |
J Thorac Cardiovasc Surg 2000;119:1246-1254 |
MPC-500 |
dog |
myocardial performance |
| Patel HJ, Pilla JJ, Polidori DJ, Pusca SV, Plappert TA, Sutton MS, Lankford EB, Acker MA |
TEN WEEKS OF RAPID VENTRICULAR PACING CREATES A LONG-TERM MODEL OF LEFT VENTRICULAR DYSFUNCTION |
J Thorac Cardiovasc Surg 2000;119:834-841 |
5F micromanometer-tipped catheter |
dog |
heart failure |
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