| AUTHORS |
TITLE |
JOURNAL |
MILLAR EQPT. |
SUBJECT |
application |
---------------------------------------------Published in 2008--------------------------------------------- |
| Jin J-K, Whittaker R, Glassy MS, Barlow SB, Gottlieb RA, Glembotski CC |
Localization of phosphorylated αB-crystallin to heart mitochondria during ischemia-reperfusion |
Am J Physiol Heart Circ Physiol, Jan 2008; 294: H337 - H344 |
Millar pressure transducer |
mouse |
mitochondrial permeability transition; cardioprotection |
| Lorenz JN, Arend LJ, Robitz R, Paul RJ, MacLennan AJ |
Vascular dysfunction in S1P2 sphingosine 1-phosphate receptor knockout mice |
Am J Physiol Regulatory Integrative Comp Physiol, Jan 2007; 292: R440 - R446 |
SPR-671 |
mouse |
lysosphingolipids; endothelium; vascular smooth muscle; blood flow; myocardial contractility |
| Kiriazis H, Wang K, Xu Q, Gao X-M, Ming Z, Su Y, Moore X-L, Lambert G, Gibbs ME, Dart AM, Du X-J |
Knockout of [beta]1- and [beta]2-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis |
British Journal of Pharmacology 153, 684 - 692 (14 Jan 2008) |
1.4-Fr Millar catheter |
mouse |
adrenoceptors |
| Xiao HD, Fuchs S, Bernstein EA, Li P, Campbell DJ, Bernstein KE |
Mice expressing ACE only in the heart show that increased cardiac angiotensin II is not associated with cardiac hypertrophy |
Am J Physiol Heart Circ Physiol, Feb 2008; 294: H659 - H667 |
SPR-671 |
mouse |
connexin; gene targeting; blood pressure; genetically modified mice |
| Esaki M, Takemura G, Kosai K, Takahashi T, Miyata S, Li L, Goto K, Maruyama R, Okada H, Kanamori H, Ogino A, Ushikoshi H, Minatoguchi S, Fujiwara T, Fujiwara H |
Treatment with an adenoviral vector encoding hepatocyte growth factor mitigates established cardiac dysfunction in doxorubicin-induced cardiomyopathy |
Am J Physiol Heart Circ Physiol, Feb 2008; 294: H1048 - H1057 |
SPR-671 |
mouse |
heart failure |
| Zhu M, Gach AA, Liu GX, Xu X, Lim CC, Zhang JX, Mao L, Chuprun K, Koch WJ, Liao R, Koren G, Blaxall BC, Mende U |
Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active Gαo* protein |
Am J Physiol Heart Circ Physiol, Mar 2008; 294: H1335 - H1347 |
1.4-Fr high-fidelity micromanometer catheter |
mouse |
G proteins; signal transduction; calcium; contraction; transgenic mice |
| Kontaridis MI, WYang W, Bence KK, Cullen D, Wang B, NBodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG |
Deletion of Ptpn11 (Shp2) in Cardiomyocytes Causes Dilated Cardiomyopathy via Effects on the Extracellular Signal–Regulated Kinase/Mitogen-Activated Protein Kinase and RhoA Signaling Pathways |
Circulation, Mar 2008; 117: 1423 - 1435 |
SPR-671 |
mouse |
cardiomyocyte signaling pathways, protein tyrosine kinases |
| Yang Y, Ma Y, Han W, Li J, Xiang Y, Liu F, Ma X,Zhang J, Fu Z, Su Y-D, Du X-J, Gao X-M |
Age-related differences in postinfarct left ventricular rupture and remodeling |
Am J Physiol Heart Circ Physiol, Apr 2008; 294: H1815 - H1822. |
1.4 F Millar catheter |
mouse |
infarct expansion; collagen; matrix metalloproteinase; inflammatory cytokines |
| Mito S, Ozono R, Oshima T, Y, Watari Y, Yamamoto Y, Brydun A, Igarashi K, Yoshizumi M |
Myocardial Protection Against Pressure Overload in Mice Lacking Bach1, a Transcriptional Repressor of Heme Oxygenase-1 |
Hypertension, Apr 2008; doi:10.1161/HYPERTENSIONAHA.107.102566 |
1.4F Millar pressure catheter |
mouse |
hypertrophy • HO-1 • mice • oxidative stress • Bach1 • remodeling |
| Drouin A, Gendron M-È, Thorin E, Gillis M-A,Mahlberg-Gaudin , Tardif J-C |
Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice |
British Journal of Pharmacology (14 Apr 2008), doi: 10.1038/bjp.2008.116, Research Paper |
Millar catheter |
mouse |
hypercholesterolaemia, vasodilatation and acetylcholine, cardiac dysfunction, metoprolol, telemetry |
| Parrish DC, Gritman K, Van Winkle DM, Woodward WR, Bader M, Habecker BA |
Postinfarct sympathetic hyperactivity differentially stimulates expression of tyrosine hydroxylase and norepinephrine transporter |
Am J Physiol Heart Circ Physiol, Jan 2008; 294: H99 - H106 |
microtipped pressure transducer (2.0 French; Millar) |
rat |
ischemia-reperfusion; sympathetic hyperactivity; autonomic |
| Chen L,Zhang J, Gan TX, Chen-Izu Y, Hasday JD, Karmazyn M, Balke CW, Scharf SM |
Left ventricular dysfunction and associated cellular injury in rats exposed to chronic intermittent hypoxia |
J Appl Physiol, Jan 2008; 104: 218 - 223 |
micromanometer-tipped catheters, 2.5 F |
rat |
obstructive sleep apnea; cardiac hypertrophy; apoptosis |
| El-Helou V, Proulx C, Gosselin H, Clement R, Mimee A, Villeneuve L, Calderone A |
Dexamethasone treatment of post-MI rats attenuates sympathetic innervation of the infarct region |
J Appl Physiol, Jan 2008; 104: 150 - 156 |
SPR-407 |
rat |
dexamethasone; neural remodeling; myocardial infarction; myofibroblasts; nerve growth factor |
| Yeih D-F, Lin L-Y, Yeh H-I, Lai Y-J, Chiang F-T, Tseng C-D, Chu S-H, Tseng Y-Z |
Temporal changes in cardiac force- and flow-generation capacity, loading conditions, and mechanical efficiency in streptozotocin-induced diabetic rats |
Am J Physiol Heart Circ Physiol, Feb 2008; 294: H867 - H874 |
2-Fr Millar catheter |
rat |
diabetes; contractile function; hemodynamics; mechanical efficiency; ventriculoarterial coupling |
| Varagic J, Frohlich ED, Susic D, Ahn J, López B, Díez J |
AT1 receptor antagonism attenuates target organ effects of salt excess in SHRs without affecting pressure |
Am J Physiol Heart Circ Physiol, Feb 2008; 294: H853 - H858 |
Micro-Tip 3F |
rat |
left ventricular function; fibrosis; coronary circulation; angiotensi II type 1 receptor blocker |
| Fregosi RF |
Influence of tongue muscle contraction and dynamic airway pressure on velopharyngeal volume in the rat |
J Appl Physiol, Mar 2008; 104: 682 - 693 |
nonmagnetic pressure transducer |
rat |
apnea; functional electrical stimulation; hypoglossal nerve; magnetic resonance imaging; pharynx; upper airway |
| Van Linthout S, Spillmann F, Riad A, Trimpert C, Lievens J, Meloni M, Escher F, Filenberg E, Demir O, Li J, Shakibaei M, Schimke I, Staudt A, Felix SB, Schultheiss H-P, De Geest B, Tschöpe C |
Human Apolipoprotein A-I Gene Transfer Reduces the Development of Experimental Diabetic Cardiomyopathy |
Circulation, Mar 2008; 117: 1563 - 1573 |
2F-tip catheter |
rat |
cardiac oxidative stress, intramyocardial inflammation, cardiac fibrosis, and cardiac apoptosis. |
| Wu M-S, Liang J-T , Lin Y-D, Wu E-T, Tseng Y-Z, Chang K-C |
Aminoguanidine prevents the impairment of cardiac pumping mechanics in rats with streptozotocin and nicotinamide-induced type 2 diabetes |
British Journal of Pharmacology (31 Mar 2008), doi: 10.1038/bjp.2008.119, Research Paper |
SPC-320 |
rat |
advanced glycation end products, aminoguanidine, maximal systolic elastance, theoretical maximum flow, streptozotocin–nicotinamide diabetic rats |
| Lee T-M, Chen C-C, Lin M-S, Chang N-C |
Effect of endothelin receptor antagonists on ventricular susceptibility in postinfarcted rats |
Am J Physiol Heart Circ Physiol, Apr 2008; 294: H1871 - H1879 |
SPR-407 |
rat |
myocardial infarction; nerve growth factor; rats; sympathetic reinnervation |
| Mito S, Ozono R, Oshima T, Yano Y, Watari Y, Yamamoto Y, Brydun A, Igarashi K, Yoshizumi M |
Myocardial Protection Against Pressure Overload in Mice Lacking Bach1, a Transcriptional Repressor of Heme Oxygenase-1 |
Hypertension, Jun 2008; 51: 1570 - 1577 |
1.4F Millar pressure catheter |
mouse |
hypertrophy • HO-1 • mice • oxidative stress • Bach1 • remodeling |
| Matsuhisa S, Otani H, Okazaki T, Yamashita K, Akita Y, Sato D, Moriguchi A, Imamura H, Iwasaka T |
Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart |
Am J Physiol Heart Circ Physiol, Jun 2008; 294: H2473 - H2479 |
2 F |
rat |
antioxidant; nitric oxide synthase |
| DeMarco VG, Habibi J, Whaley-Connell AT, Schneider RI, Heller RL, Bosanquet JP, Hayden MR, Delcour K, Cooper SA, Andresen BT, Sowers JR, Dellsperger KC |
Oxidative stress contributes to pulmonary hypertension in the transgenic (mRen2)27 rat |
Am J Physiol Heart Circ Physiol, Jun 2008; 294: H2659 - H2668. |
Mikro-tip catheter |
rat |
renin; angiotensin II; NADPH oxidase |
| Yu Q, Nguyen T, Ogbi M, Caldwell RW, Johnson JA |
Differential loss of cytochrome-c oxidase subunits in ischemia-reperfusion injury: exacerbation of COI subunit loss by PKC-ε inhibition |
Am J Physiol Heart Circ Physiol, Jun 2008; 294: H2637 - H2645 |
water-filled balloon-tipped Millar catheter |
rat |
preconditioning; protein kinase C; cytochrome oxidase subunit; coronary ligation; mitochondria |
| Kleiber AC, Zheng H, Schultz HD, Peuler JD, Patel KP |
Exercise training normalizes enhanced glutamate-mediated sympathetic activation from the PVN in heart failure |
Am J Physiol Regulatory Integrative Comp Physiol, Jun 2008; 294: R1863 - R1872 |
Mikro-Tip catheter |
rat |
paraventricular nucleus; N-methyl-D-aspartic acid receptors; sympathetic nerve activity |
| Mczewski M, Mczewska J, Duda M |
Hypercholesterolaemia exacerbates ventricular remodelling after myocardial infarction in the rat: role of angiotensin II type 1 receptors |
British Journal of Pharmacology (09 Jun 2008), doi: 10.1038/bjp.2008.218 |
SPC-320 |
rat |
myocardial infarction, hypercholesterolaemia, statin, sartan, heart failure, remodelling, rat |
| Aubin M-C, Lajoie C, Clément R, Gosselin H, Calderone A, Perrault LP |
Female Rats Fed a High-Fat Diet Were Associated with Vascular Dysfunction and Cardiac Fibrosis in the Absence of Overt Obesity and Hyperlipidemia: Therapeutic Potential of Resveratrol |
J. Pharmacol. Exp. Ther. 2008 325: 961-968 |
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|
|
| Whiteaker P, Marks MJ, Christensen S, Dowell C, Collins AC, McIntosh MJ |
Synthesis and Characterization of 125 I-α-Conotoxin ArIB[V11L;V16A], a Selective α7 Nicotinic Acetylcholine Receptor Antagonist |
J. Pharmacol. Exp. Ther. 2008 325: 910-919 |
|
mouse |
|
| Oudit G Y,Kassiri Z, Zhou J, Liu QC, Liu PP, Backx PH, Dawood F, Crackower MA, Scholey JW, Penninger JM |
Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress |
Cardiovasc Res, 1 June 2008; 78: 505 - 514 |
1.4 French Millar catheter |
mouse |
Heart failure; Hypertrophy; Angiogenesis; Angiotensin II; Signalling |
---------------------------------------------Published in 2007--------------------------------------------- |
| Knaus A, Zong X, Beetz N, Jahns R, Lohse MJ, Biel M, Hein L |
Direct Inhibition of Cardiac Hyperpolarization-Activated Cyclic Nucleotide-Gated Pacemaker Channels by Clonidine |
Circulation, Jan 2007; doi:10.1161/CIRCULATIONAHA.106.667675 |
1.4F Millar microtip device |
mouse |
receptors, adrenergic, alpha • heart rate • ion channels • pharmacology |
| Li Y, Takemura G, Okada H, Miyata S, Kanamori H, Maruyama R, Esaki M, Li L, Ogino A, Ohno T, Kondo T, Nakagawa M, Minatoguchi S, Fujiwara T, Fujiwara H |
ANG II type 1A receptor signaling causes unfavorable scar dynamics in the postinfarct heart |
Am J Physiol Heart Circ Physiol, Feb 2007; 292: H946 - H953 |
SPR-671 |
mouse |
angiotensin II; apoptosis; granulation tissue; heart failure; myocardial infarction; myofibroblast; scar |
| Knaus A, Zong X, Beetz N, Jahns R, Lohse MJ, Biel M,Lutz Hein L |
Direct Inhibition of Cardiac Hyperpolarization-Activated Cyclic Nucleotide–Gated Pacemaker Channels by Clonidine |
Circulation, Feb 2007; 115: 872 - 880 |
1.4F Millar microtip device |
mouse |
HCN channel inhibitors |
| Sekiguchi K, Tian Q, Ishiyama M, Burchfield J, Gao F, Mann DL, Barger PM |
Inhibition of PPAR-α activity in mice with cardiac-restricted expression of tumor necrosis factor: potential role of TGF-β/Smad3 |
Am J Physiol Heart Circ Physiol, Mar 2007; 292: H1443 - H1451 |
1.4-Fr microtipped Millar catheter |
mouse |
metabolism; inflammation; genes; signal transduction |
| Zhao X, Chen Y-R, He G, Zhang A, Druhan LJ, Strauch AR, Zweier JL |
Endothelial nitric oxide synthase (NOS3) knockout decreases NOS2 induction, limiting hyperoxygenation and conferring protection in the postischemic heart |
Am J Physiol Heart Circ Physiol, Mar 2007; 292: H1541 - H1550 |
SPR-261, 1.4 Fr |
mouse |
oxygen; superoxide; peroxynitrite; mitochondria; electron paramagnetic resonance; ischemia-reperfusion |
| Hanada K, Vermeij M, Garinis GA, de Waard MC, Kunen MGS, Myers L, Maas A, Duncker DJ, Meijers C, Dietz HC, Kanaar R, Essers J |
Perturbations of Vascular Homeostasis and Aortic Valve Abnormalities in Fibulin-4 Deficient Mice |
Circ. Res., Mar 2007; 100: 738 - 746 |
SPR-671 |
mouse |
aneurysm • aortic valve • mouse |
| Hansmann G, Wagner RA, Schellong S, Perez VAdJ, Urashima T, Wang L, Sheikh AY, Suen RS, Stewart DJ, Rabinovitch M |
Pulmonary Arterial Hypertension Is Linked to Insulin Resistance and Reversed by Peroxisome Proliferator–Activated Receptor-γ Activation |
Circulation, Mar 2007; 115: 1275 - 1284 |
1.4F |
mouse |
insulin resistance, low plasma adiponectin levels, and deficiency of apoE |
| Said SI, Hamidi SA, Dickman KG, Szema AM, Lyubsky S, Lin RZ, Jiang Y-P, Chen JJ, Waschek JA, Kort S |
Moderate Pulmonary Arterial Hypertension in Male Mice Lacking the Vasoactive Intestinal Peptide Gene |
Circulation, Mar 2007; 115: 1260 - 1268 |
1.4F 3-cm Mikro-Tip catheter |
mouse |
VIP knockout (VIP–/–) |
| Martino TA, Tata N, Belsham DD, Chalmers J, Straume M, Lee P, Pribiag H, Khaper N, Liu PP, Dawood F, Backx PH, Ralph MR, Sole MJ |
Disturbed Diurnal Rhythm Alters Gene Expression and Exacerbates Cardiovascular Disease With Rescue by Resynchronization |
Hypertension, Mar 2007; doi:10.1161/HYPERTENSIONAHA.106.083568 |
1.4 French catheter |
mouse |
cardiac hypertrophy • renin-angiotensin-aldosterone system pathway • remodeling • gene expression microarrays •circadian |
| Belke DD, Swanson E, Suarez J, Scott BT, Stenbit AE, Dillmann WH |
Increased expression of SERCA in the hearts of transgenic mice results in increased oxidation of glucose |
Am J Physiol Heart Circ Physiol, Apr 2007; 292: H1755 - H1763 |
2-Fr miniature pressure transducer |
mouse |
mitochondrial calcium; pyruvate dehydrogenase; cardiac energetics; sarco(endo)plasmic reticulum calcium-adenosine 5'-triphosphatase |
| Kanamori H, Takemura H, Li Y, Okada H, Maruyama R, Aoyama T, Miyata S, Esaki M, Ogino A, Nakagawa M, Ushikoshi H, Kawasaki M, Minatoguchi S, Fujiwara H |
Inhibition of Fas-associated apoptosis in granulation tissue cells accompanies attenuation of postinfarction left ventricular remodeling by olmesartan |
Am J Physiol Heart Circ Physiol, May 2007; 292: H2184 - H2194. |
SPR-671 |
mouse |
angiotensin; apoptosis; heart failure; myocardial infarction |
| Bendall JK, Rinze R, Adlam D, Tatham AL, de Bono J, Channon KM |
Endothelial Nox2 Overexpression Potentiates Vascular Oxidative Stress and Hemodynamic Response to Angiotensin II: Studies in Endothelial-Targeted Nox2 Transgenic Mice |
Circ. Res., Apr 2007; 100: 1016 - 1025 |
Millar catheter system |
mouse |
NADPH oxidase • oxidative stress • endothelium • hemodynamics |
| Funakoshi H, Zacharia LC, Tang Z, Zhang J, Lee LL, Good JC, Herrmann DE, Higuchi Y, Koch WJ, Jackson EK, Chan TO, Feldman AM |
A1 Adenosine Receptor Upregulation Accompanies Decreasing Myocardial Adenosine Levels in Mice With Left Ventricular Dysfunction |
Circulation, May 2007; 115: 2307 - 2315 |
1.4F micromanometer catheter |
mouse |
myocardial adenosine system |
| Martino TA, Tata N, Belsham DD, Chalmers J, Straume M, Lee P, Pribiag H, Khaper N, Liu PP, Dawood F, Backx PH, Ralph MR, Sole MJ |
Disturbed Diurnal Rhythm Alters Gene Expression and Exacerbates Cardiovascular Disease With Rescue by Resynchronization |
Hypertension, May 2007; 49: 1104 - 1113 |
1.4 French catheter |
mouse |
cardiac hypertrophy • renin–angiotensin–aldosterone system pathway • remodeling • gene expression microarrays • circadian |
| Monden Y, Kubota T, Inoue T, Tsutsumi T, Kawano S, Ide T, Tsutsui T, Sunagawa K |
Tumor necrosis factor-α is toxic via receptor 1 and protective via receptor 2 in a murine model of myocardial infarction |
Am J Physiol Heart Circ Physiol, Jul 2007; 293: H743 - H753 |
1.4-Fr micromanometer-tipped catheter |
mouse |
cytokines; heart failure; remodeling; interstitial fibrosis |
| Buys ES, Raher MJ, Blake SL, Neilan TG, Graveline AR, Passeri JJ, Llano M, Perez-Sanz TM, Ichinose F, Janssens S, Zapol WM, Picard MH, Bloch KD, Scherrer-Crosbie M |
Cardiomyocyte-restricted restoration of nitric oxide synthase 3 attenuates left ventricular remodeling after chronic pressure overload |
Am J Physiol Heart Circ Physiol, Jul 2007; 293: H620 - H627 |
SPR-671 |
mouse |
echocardiography; heart failure; hypertrophy; mice |
| Wagenseil JE, Knutsen RH, Li DY, Mecham RP |
Elastin-insufficient mice show normal cardiovascular remodeling in 2K1C hypertension despite higher baseline pressure and unique cardiovascular architecture |
Am J Physiol Heart Circ Physiol, Jul 2007; 293: H574 - H582 |
catheter |
mouse |
arterial mechanics; extracellular matrix; high blood pressure; cardiac hypertrophy; two-kidney, one-clip hypertension |
| Nakaoka Y, Nishida K, Narimatsu M, Kamiya A, Minami T, Sawa H, Okawa K, Fujio Y, Koyama T, Maeda M, Sone M, Yamasaki S, Arai Y, Koh GY, Kodama T, Hirota H, Otsu K, Hirano T, Mochizuki N |
Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling |
J. Clin. Invest., Jul 2007; 117: 1771 - 1781 |
1.4 French high-fidelity pressure transducer catheter |
mouse |
scaffolding adaptor proteins |
| Kuba K, Zhang L, Imai Y, Arab S, Chen M, Maekawa Y, Leschnik M, Leibbrandt A, Makovic M, Schwaighofer J, Beetz N, Musialek R, Neely GG, Komnenovic V, Kolm U, Metzler B, Ricci R, Hara H, Meixner A, Nghiem M, Chen X, Dawood F, Wong KM, Sarao R, Cukerman E, Kimura A, Hein L, Thalhammer J, Liu PP, Penninger JM |
Impaired Heart Contractility in Apelin Gene–Deficient Mice Associated With Aging and Pressure Overload |
Circ. Res., Aug 2007; 101: e32 - e42 |
1.4 French Millar catheter, TCP-500 |
mouse |
aging • angiotensin • cardiac failure • cardiac function • pressure overload |
| Vermeersch P, Buys E, Pokreisz P, Marsboom G, Ichinose F, Sips P, Pellens M, Gillijns H, Swinnen M, Graveline A, Collen D, Dewerchin M, Brouckaert P, Bloch KD, Janssens S |
Soluble Guanylate Cyclase-α1 Deficiency Selectively Inhibits the Pulmonary Vasodilator Response to Nitric Oxide and Increases the Pulmonary Vascular Remodeling Response to Chronic Hypoxia |
Circulation, Aug 2007; 116: 936 - 943 |
1.4F Millar catheter |
mouse |
guanylate cyclase • nitric oxide • hypoxia • hypertension, pulmonary • remodeling |
| Huggins GS, Lepore JJ, Greytak S, Patten R, McNamee R, Aronovitz M, Wang PJ, Reed GL |
The CREB leucine zipper regulates CREB phosphorylation, cardiomyopathy, and lethality in a transgenic model of heart failure |
Am J Physiol Heart Circ Physiol, Sep 2007; 293: H1877 - H1882 |
1.4-Fr Millar pressure catheter |
mouse |
adenosine 3',5'-cyclic monophosphate responsive element binding protein |
| Palmer LA, Doctor A, Chhabra P, Sheram M:,Laubach VE, Karlinsey MZ, Forbes MS, Macdonald T, Gaston B |
S-Nitrosothiols signal hypoxia-mimetic vascular pathology |
J. Clin. Invest., Sep 2007; 117: 2592 - 2601 |
Millar 1.4 F catheter/transducer |
mouse |
chronic NAC administration, pulmonary arterial hypertension |
| Khan M, Kutala VK, Vikram DS, Wisel S, Chacko SM, Kuppusamy ML, Mohan IK, Zweier JL, Kwiatkowski P, Kuppusamy P |
Skeletal myoblasts transplanted in the ischemic myocardium enhance in situ oxygenation and recovery of contractile function |
Am J Physiol Heart Circ Physiol, Oct 2007; 293: H2129 - H2139 |
SPR-1000 |
mouse |
ischemic heart; myocardial infarction; electron paramagnetic resonance oximetry; OxySpin |
| Ogino A, Takemura G, Kanamori H, Okada H, Maruyama R, Miyata S, Esaki M, Nakagawa M, Aoyama T, Ushikoshi H, Kawasaki M, Minatoguchi S, Fujiwara T, Fujiwara H |
Amlodipine inhibits granulation tissue cell apoptosis through reducing calcineurin activity to attenuate postinfarction cardiac remodeling |
Am J Physiol Heart Circ Physiol, Oct 2007; 293: H2271 - H2280 |
SPR 671 |
mouse |
Ca2+ channels; heart failure |
| Gendron M-E, Thorin E |
A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice |
Am J Physiol Heart Circ Physiol, Oct 2007; 293: H2508 - H2515 |
Millar catheter |
mouse |
nitric oxide; cyclooxygenase; reactive oxygen species |
| Bostick B, Yue Y, Long C, Duan D |
Prevention of Dystrophin-Deficient Cardiomyopathy in Twenty-One-Month-Old Carrier Mice by Mosaic Dystrophin Expression or Complementary Dystrophin/Utrophin Expression |
Circ. Res., Oct 2007; doi:10.1161/CIRCRESAHA.107.162982 |
closed-chest Millar catheter |
mouse |
cardiomyopathy • gene therapy • myocardium • genetics • heart disease |
| Desjardins J-F, Teichert-Kuliszewska K, Quan A, Verma S, Stewart DJ, Parker TG |
Abstract 444: Absence of S100A1 in Mice is Associated With a Hypertensive Phenotype Dependent on Both Gender and Endothelial Function |
Circulation, Oct 2007; 116: II_74 |
Millar catheter |
mouse |
cardiac muscle Ca2+ homeostasis |
| Partovian C, Zhuang ZW, Martin KA, Simons M |
Abstract 326: Syndecan-4 Knockout Mice Exhibit Decreased eNOS Activity And Increased Blood Pressure Via Disruption Of mTOR Complex Assembly In Raft Domains |
Circulation, Oct 2007; 116: II_47 |
Millar transducer |
mouse |
eNOS activity and angiogenesis |
| Horstkotte J, Lange P, Schroeder M, Schneider M, Perisic T, Hinkel R, Kiermayer C, Brielmeier M, Boekstegers P, Markus C, Kupatt C |
Abstract 1010: Endogenous Mitochondrial, But Not Cytosolic Thioredoxin Reductase Protects Against Myocardial Ischemia-reperfusion Injury |
Circulation, Oct 2007; 116: II_201 |
Millar tip catheter |
mouse |
protective ROS-scavenging, knock-out mouse |
| Iwasaki M, Koyanagi M, Rapp S, Schuetz C, Bushoven P, Schranz D, Galvez BG, Cossu G, Zeiher AM, Urbich C, Dimmeler S |
Abstract 855: Circulating Mesoangioblasts Differentiate Into Cardiac Myocytes And Improve Function After Acute Myocardial Infarction |
Circulation, Oct 2007; 116: II_166 |
Millar catheter |
mouse |
Cardiac Regeneration/Cellular Therapy-Experimental: Stem Cell Origin and Myocardial Homing, nude mouse |
| Tang YL, Shen L, Qian K, Phillips MI |
Abstract 859: Hypoxia-activated CXCR4 Expression In Cardiac Progenitor Cells For Replenishing Stem Cell Pool In Acute Ischemic Myocardium |
Circulation, Oct 2007; 116: II_167 |
Millar catheter |
mouse |
Cardiac Regeneration/Cellular Therapy-Experimental: Stem Cell Origin and Myocardial Homing |
| Urashima T, Zhao M, Wagner R, Fajardo G, Farahani S, Quertermous T, Bernstein D |
Abstract 3129: Molecular and Physiologic Characterization of RV Remodeling and Failure in a Murine Model of Mild, Moderate and Severe Pulmonary Stenosis |
Circulation, Oct 2007; 116: II_702 |
Millar catheter |
mouse |
Mechanical Regulation of the Right Side of the Heart in Congenital Heart Disease: Influence of Age and Hemodynamic Load |
| Diwan A, Krenz M, Syed FM, Wansapura J, Ren X, Koesters AG, Li H, Kirshenbaum LA, Hahn HS, Robbins J, Jones WK, Dorn II GW |
Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice |
J. Clin. Invest., Oct 2007; 117: 2825 - 2833 |
1.4 French Millar solid-state catheters |
mouse |
proapoptotic gene |
| Hambleton M, York A, Sargent MA, Kaiser RA, Lorenz JN, Robbins J, Molkentin JD |
Inducible and myocyte-specific inhibition of PKC enhances cardiac contractility and protects against infarction-induced heart failure |
Am J Physiol Heart Circ Physiol, Dec 2007; 293: H3768 - H3771 |
1.4 F Millar catheter |
mouse |
protein kinase C; signaling; myocardial infarction |
| El-Bizri N, Wang L, Merklinger SL, Guignabert C, Desai T, Urashima T, Sheikh AY, Knutsen RH, Mecham RP, Mishina Y, Rabinovitch M |
Smooth Muscle Protein 22–Mediated Patchy Deletion of Bmpr1a Impairs Cardiac Contractility but Protects Against Pulmonary Vascular Remodeling |
Circ. Res., Dec 2007; doi:10.1161/CIRCRESAHA.107.161059 |
1.4F Millar catheter |
mouse |
Bmpr1a (Alk3) • pulmonary hypertension • hypoxia • vascular remodeling • smooth muscle cell • pericytes • proliferation • apoptosis • transgenic mice |
| Rose RA,Kabir MG, Backx PH |
Altered Heart Rate and Sinoatrial Node Function in Mice Lacking the cAMP Regulator Phosphoinositide 3-Kinase-g |
Circ. Res., Dec 2007; 101: 1274 - 1282. |
pressure catheter |
mouse |
ion channels • electrophysiology • action potentials • arrhythmia |
| Li L, Takemura G, Li Y, Miyata S, Esaki M, Okada H, Kanamori H, Ogino A, Maruyama R, Nakagawa M, Minatoguchi S, Fujiwara T, Fujiwara H, Takemura G |
Granulocyte colony-stimulating factor improves left ventricular function of doxorubicin-induced cardiomyopathy |
Laboratory Investigation 87, 440 - 455 (05 Mar 2007) |
SPR 671 |
mouse |
cardiomyopathy, cytokines, doxorubicin, ERK, G-CSF, heart failure |
| Sanbe A, Tanaka Y, Fujiwara Y, Tsumura H, Yamauchi J, Cotecchia S, Koike K, Tsujimoto G, Tanoue A |
α1-Adrenoceptors are required for normal male sexual function |
British Journal of Pharmacology 152, 332 - 340 (01 Oct 2007) |
SPR-671 |
mouse |
α1-Adrenoceptor, ejaculation, vas deferens |
| Johns, DG Behm DJ, Walker DJ, Ao Z, Shapland EM, Daniels DA, Riddick M, Dowell S, Staton PC, Green P, Shabon U, Bao W, Aiyar N, Yue T-L, Brown AJ, Morrison AD, Douglas SA |
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects |
British Journal of Pharmacology 152, 825 - 831 (20 Aug 2007) |
SPR-671 |
mouse |
GPR55, cannabinoid receptors, abnormal cannabidiol, CBx receptor |
| Reddy MK, Schultz HD, Zheng H, Patel KP |
Altered nitric oxide mechanism within the paraventricular nucleus contributes to the augmented carotid body chemoreflex in heart failure |
Am J Physiol Heart Circ Physiol, Jan 2007; 292: H149 - H157 |
2-Fr micromanometer-tipped catheter |
rat |
renal sympathetic nerve activity; phrenic nerve activity; hypothalamus |
| Susic D, Varagic J, Ahn J, Matavelli L, Frohlich ED |
Long-term mineralocorticoid receptor blockade reduces fibrosis and improves cardiac performance and coronary hemodynamics in elderly SHR |
Am J Physiol Heart Circ Physiol, Jan 2007; 292: H175 - H179 |
catheter-tip transducer |
rat |
aldosterone; myocardial fibrosis; left ventricular diastolic function; minimal vascular resistance; antihypertensive/diuretics |
| Pan Y-X, Gao L, Wang W-Z, Zheng H, Liu D, Patel KP, Zucker IH, Wang W |
Exercise Training Prevents Arterial Baroreflex Dysfunction in Rats Treated With Central Angiotensin II |
Hypertension, Jan 2007; doi:10.1161/01.HYP.0000256955.74461.93 |
SPR-524 |
rat |
exercise • baroreflex • sympathetic nerve activity • reactive oxygen species • AT1 receptor |
| Li J, Gao Z, Kehoe V, Sinoway LI |
Interstitial K+ concentration in active muscle after myocardial infarction |
Am J Physiol Heart Circ Physiol, Feb 2007; 292: H808 - H813 |
2-Fr microMillar pressure transducer catheter |
rat |
sympathetic nervous system; exercise; blood flow |
| Gao Z, Xing J, Sinoway L, Li J |
P2X receptor-mediated muscle pressor reflex in myocardial infarction |
Am J Physiol Heart Circ Physiol, Feb 2007; 292: H939 - H945 |
Millar catheter |
rat |
exercise; blood pressure; sympathetic nervous system; dorsal root ganglion; heart failure |
| Rennison JH, McElfresh TA, Okere IC, Vazquez EJ, Patel HV, Foster AB, Patel KK, Chen Q, Hoit BD, Tserng K-Y, Hassan MO, Hoppel CL, Chandler MP |
High-fat diet postinfarction enhances mitochondrial function and does not exacerbate left ventricular dysfunction |
Am J Physiol Heart Circ Physiol, Mar 2007; 292: H1498 - H1506 |
3.5 Fr |
rat |
oxidative phosphorylation; electron transport chain; ceramide; lipotoxicity |
| Helwig BG, Musch TI, Craig RA, Kenney MJ |
Increased interleukin-6 receptor expression in the paraventricular nucleus of rats with heart failure |
Am J Physiol Regulatory Integrative Comp Physiol, Mar 2007; 292: R1165 - R1173. |
2-Fr catheter-tip pressure manometer |
rat |
signal transduction; gp130; hypothalamic-pituitary axis |
| Sethi R, Saini HK, Wang X, Elimban V, Dhalla NS |
Dependence of changes in β-adrenoceptor signal transduction on type and stage of cardiac hypertrophy |
J Appl Physiol, Mar 2007; 102: 978 - 984 |
SPR-249 |
rat |
pressure overload; volume overload; cardiac function; β-adrenoceptors; adenylyl cyclase; intracellular calcium concentr |
| Pan Y-X, Gao L, Wang W-Z, Zheng H, Liu D, Patel KP, Zucker IH, Wang W |
Exercise Training Prevents Arterial Baroreflex Dysfunction in Rats Treated With Central Angiotensin I |
Hypertension, Mar 2007; 49: 519 - 527 |
SPR-524 |
rat |
exercise • baroreflex • sympathetic nerve activity • reactive oxygen species • AT1 receptor |
| Milano G, Morel S, Bonny C, Samaja M, von Segesser LK, Nicod P, Vassalli G |
A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo |
Am J Physiol Heart Circ Physiol, Apr 2007; 292: H1828 - H1835 |
MPC-500 |
rat |
myocardium; mitogen-activated protein kinases; apoptosis; isolated |
| Simpson JA, Iscoe S |
Cardiorespiratory failure in rat induced by severe inspiratory resistive loading |
J Appl Physiol, Apr 2007; 102: 1556 - 1564 |
SPR 524 |
rat |
diaphragm; fatigue; heart; injury; troponin |
| Cosson E, Herisse M, Laude E, Thomas F, Valensi P, Attali J-R, Safar ME, Dabire H |
Aortic stiffness and pulse pressure amplification in Wistar-Kyoto and spontaneously hypertensive rats |
Am J Physiol Heart Circ Physiol, May 2007; 292: H2506 - H2512 |
SPR-330 |
rat |
pulse wave velocity; body weight; conscious rat; autonomic nervous system |
| Garg P, Martin CF, Elms SC, Gordon FJ, Wall SM, Garland CJ, Sutliff RL, O'Neill WC |
Effect of the Na-K-2Cl cotransporter NKCC1 on systemic blood pressure and smooth muscle tone |
Am J Physiol Heart Circ Physiol, May 2007; 292: H2100 - H2105 |
SPR-671 |
rat |
resistance arteries; hypertension; bumetanide |
| Chicco AJ, Johnson MS, Armstrong CJ, Lynch JM, Gardner RT, Fasen GS, Gillenwater CP, Moore RL |
Sex-specific and exercise-acquired cardioprotection is abolished by sarcolemmal KATP channel blockade in the rat heart |
Am J Physiol Heart Circ Physiol, May 2007; 292: H2432 - H2437 |
3-Fr pressure-transducing catheter |
rat |
ischemia; infarction; sex differences; gender |
| Gao E, Boucher M, Chuprun JK, Zhou R-H, Eckhart AD, Koch WJ |
Darbepoetin alfa, a long-acting erythropoietin analog, offers novel and delayed cardioprotection for the ischemic heart |
Am J Physiol Heart Circ Physiol, Jul 2007; 293: H60 - H68 |
2-Fr micromanometer |
rat |
myocardial ischemia; ischemia-reperfusion injury; apoptosis |
| van Hees HWH, van der Heijden HFM, Ottenheijm CAC, Heunks LMA, Pigmans CJC, Verheugt FWA, Brouwer RMHJ, Dekhuijzen PNR |
Diaphragm single-fiber weakness and loss of myosin in congestive heart failure rats |
Am J Physiol Heart Circ Physiol, Jul 2007; 293: H819 - H828 |
SPC-330 |
rat |
skinned muscle single fibers; cross-bridge cycling kinetics; Ca2+ sensitivity; proteasome; caspase-3 |
| Ito T, Okada T, Mimuro J, Miyashita H, Uchibori R, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Sakata Y, Shimada K, Ozawa K |
Adenoassociated Virus-Mediated Prostacyclin Synthase Expression Prevents Pulmonary Arterial Hypertension in Rats |
Hypertension, Jul 2007; doi:10.1161/HYPERTENSIONAHA.107.091348 |
SPC-320 |
rat |
hypertension • pulmonary • gene therapy • remodeling • prostacyclin synthase |
| Henkens IR, Mouchaers KTB, Vliegen HW, van der Laarse WJ, Swenne CA, Maan AC, Draisma HHM, Schalij I, van der Wall EE, Schalij MJ, Vonk-Noordegraaf A |
Early changes in rat hearts with developing pulmonary arterial hypertension can be detected with three-dimensional electrocardiography |
Am J Physiol Heart Circ Physiol, Aug 2007; 293: H1300 - H1307 |
Millar pressure catheter |
rat |
right ventricular hypertrophy; monocrotaline; electrocardiogram |
| Lee T-M, Lin M-S, Chang N-C |
Inhibition of histone deacetylase on ventricular remodeling in infarcted rats |
Am J Physiol Heart Circ Physiol, Aug 2007; 293: H968 - H977 |
SPR-407 |
rat |
hypertrophy; infarction |
| Xing J, Koba S, Kehoe V, Gao Z, Rice K, King N, Sinoway L, Li J |
Interstitial norepinephrine concentrations in skeletal muscle of ischemic heart failure |
Am J Physiol Heart Circ Physiol, Aug 2007; 293: H1190 - H1195 |
2-Fr micro-Millar pressure transducer catheter |
rat |
nervous system; sympathetic; exercise; blood flow |
| Yamamoto T, Shirayama T, Sakatani T, Takahashi T, Tanaka H, Takamatsu T, Spitzer KW, Matsubara H |
Enhanced activity of ventricular Na+-HCO3– cotransport in pressure overload hypertrophy |
Am J Physiol Heart Circ Physiol, Aug 2007; 293: H1254 - H1264 |
Microtip catheter |
rat |
cardiac myocytes; intracellular pH regulation; messenger ribonucleic acid; polymerase chain reaction |
| Schultz RL, Swallow JG, Waters RP, Kuzman JA, Redetzke RA, Said S, de Escobar GM, Gerdes AM |
Effects of Excessive Long-Term Exercise on Cardiac Function and Myocyte Remodeling in Hypertensive Heart Failure Rats |
Hypertension, Jun 2007; doi:10.1161/HYPERTENSIONAHA.106.086371 |
Millar Mikro-tip catheter |
rat |
hypertension • heart failure • exercise • hypertrophy • myocytes • voluntary wheel running • SHHF |
| Ito T, Okada T, Miyashita H, Nomoto T, Nonaka-Sarukawa M, Uchibori R, Maeda Y, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Shimada K, Ozawa K |
Interleukin-10 Expression Mediated by an Adeno-Associated Virus Vector Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats |
Circ. Res., Aug 2007; doi:10.1161/CIRCRESAHA.107.153023 |
SPC-320 |
rat |
pulmonary hypertension • interleukins • gene therapy • inflammation • vascular smooth muscle cell proliferation |
| Chandler MP, Morgan EE, McElfresh TA, Kung TA, Rennison JH, Hoit BD, Young ME |
Heart failure progression is accelerated following myocardial infarction in type 2 diabetic rats |
Am J Physiol Heart Circ Physiol, Sep 2007; 293: H1609 - H1616 |
3.5-Fr pressure transducer |
rat |
contractile function; left ventricular remodeling; gene expression |
| Ito T, Okada T, Miyashita H, Nomoto T, Nonaka-Sarukawa M, Uchibori R, Maeda Y, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Shimada K, Ozawa K |
Interleukin-10 Expression Mediated by an Adeno-Associated Virus Vector Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats |
Circ. Res., Sep 2007; 101: 734 - 741 |
SPC-320 |
rat |
pulmonary hypertension • interleukins • gene therapy • inflammation • vascular smooth muscle cell proliferation |
| Yildirim Y, Naito H, Didié M, Karikkineth BC, Biermann D, Eschenhagen T, Zimmermann W-H |
Development of a Biological Ventricular Assist Device: Preliminary Data From a Small Animal Model |
Circulation, Sep 2007; 116: I-16 - I-23 |
Millar-tip catheter |
rat |
tissue engineering • myocardium • cardiomyocyte • regeneration • transplantation |
| Sartório CL, Fraccarollo D, Galuppo P, Leutke M, Ertl G, Stefanon I, Bauersachs J |
Mineralocorticoid Receptor Blockade Improves Vasomotor Dysfunction and Vascular Oxidative Stress Early After Myocardial Infarction |
Hypertension, Sep 2007; doi:10.1161/HYPERTENSIONAHA.107.093450 |
micromanometer |
rat |
aldosterone • acute myocardial infarction • endothelial dysfunction • oxidative stress |
| Ito T, Okada T, Mimuro J, Miyashita H, Uchibori R, Urabe M, Mizukami H, Kume A, Takahashi M, Ikeda U, Sakata Y, Shimada K, Ozawa K |
Adenoassociated Virus–Mediated Prostacyclin Synthase Expression Prevents Pulmonary Arterial Hypertension in Rats |
Hypertension, Sep 2007; 50: 531 - 536 |
SPC-320 |
rat |
hypertension • pulmonary • gene therapy • remodeling • prostacyclin synthase |
| Farahmand P, Weisel RD, Menasche P, Li R-K |
Abstract 2673: Myoblast Transplantation Improves Cardiac Function Whether the Cells are Implanted Early or Late After Coronary Ligation |
Circulation, Oct 2007; 116: II_592 |
Millar catheter |
rat |
myocardial infarction |
| Behnke BJ, Delp MD, Poole DC, Musch TI |
Aging potentiates the effect of congestive heart failure on muscle microvascular oxygenation |
J Appl Physiol, Nov 2007; 103: 1757 - 1763 |
2-Fr catheter-tip pressure manometer |
rat |
heart failure; skeletal muscle; oxygen exchange |
| Sartório CL, Fraccarollo D, Galuppo P, Leutke M, Ertl G, Stefanon I, Bauersachs J |
Mineralocorticoid Receptor Blockade Improves Vasomotor Dysfunction and Vascular Oxidative Stress Early After Myocardial Infarction |
Hypertension, Nov 2007; 50: 919 - 925 |
micromanometer |
rat |
aldosterone • acute myocardial infarction • endothelial dysfunction • oxidative stress |
| Chen-Izu Y, Chen L, Bányász T, McCulle SL, Norton B, Scharf SM, Agarwal A, Patwardhan A, zu LT, Balke CW |
Hypertension-induced remodeling of cardiac excitation-contraction coupling in ventricular myocytes occurs prior to hypertrophy development |
Am J Physiol Heart Circ Physiol, Dec 2007; 293: H3301 - H3310 |
SPR-249A, SPR-671 |
rat |
heart failure; action potential; L-type Ca2+ channel; ryanodine receptor |
| Lee T-M, Lin M-S, Chang N-C |
Effect of pravastatin on sympathetic reinnervation in postinfarcted rats |
Am J Physiol Heart Circ Physiol, Dec 2007; 293: H3617 - H3626 |
SPR-407 |
rat |
immunohistochemistry; ion channels; myocardial infarction; norepinephrine; polymerase chain reaction |
| Hydock DS, Lien C-Y, Schneider CM, Hayward R |
Effects of voluntary wheel running on cardiac function and myosin heavy chain in chemically gonadectomized rats |
Am J Physiol Heart Circ Physiol, Dec 2007; 293: H3254 - H3264 |
SPR-671 |
rat |
echocardiography; myosin heavy chain; orchiectomy; ovariectomy; sex hormones |
| Chang K-C, Liang J-T, Tseng C-D, Wu E-T, Hsu K-L, Wu M-S, Lin Y-T, Tseng Y-Z |
Aminoguanidine prevents fructose-induced deterioration in left ventricular?arterial coupling in Wistar rats |
British Journal of Pharmacology 151, 341 - 346 (02 Apr 2007) |
SPC-320 |
rat |
aminoguanidine, effective arterial volume elastance, fructose loading, end-systolic elastance, ventricular–arterial coupling |
| |
---------------------------------------------Published in 2006--------------------------------------------- |
| Donath S, Li P, Willenbockel C, Al-Saadi N, Gross V, Willnow T, Bader M, Martin U, Bauersachs J, Wollert KC, Dietz R, von Harsdorf R |
Apoptosis Repressor With Caspase Recruitment Domain Is Required for Cardioprotection in Response to Biomechanical and Ischemic Stress |
Circulation, Mar 2006; 113: 1203 - 1212 |
high-fidelity catheter tip transducer, 1.4F |
mouse |
apoptosis, heart failure, hypertophy, ischemia, myocardial infarction |
| Peng X, Kraus MS, Wei H, Shen T-L, Pariaut R, Alcaraz A, Ji G, Cheng L, Yang Q, Kotlikoff MI, Chen J, Chien K, Gu H, Guan J-L |
Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice |
J Clin Invest. 2006 January 4; 116(1): 217–227 |
1.4-F Millar catheter–tip micromanometer catheter |
mouse |
cytoplasmic tyrosine kinase, CFKO |
| Stauffer BL, Konhilas JP, Luczak ED, Leinwand LA |
Soy diet worsens heart disease in mice |
J. Clin. Invest. 116:209-216 (2006). |
1.4-fr Millar Mikro-tip pressure transducer |
mouse |
glycogen synthase kinase 3ß, caspase-3 activation, fibrosis, ß-myosin heavy chain, hypertrophic cardiomyopathy |
| Lindsey ML, Escobar GP, Dobrucki LW, Goshorn DK, Bouges S, Mingoia JT, McClister Jr DM, Su H, Gannon J, MacGillivray C, Lee RT, Sinusas AJ, Spinale FG |
Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction |
Am J Physiol Heart Circ Physiol, Jan 2006; 290: H232 - H239 |
SPR-671 |
mouse |
leukocytes; remodeling; imaging |
| Li Y, Takemura G, Okada H, Miyata S, Esaki M, Maruyama R, Kanamori H, Li L, Ogino A, Misao Y, Khai NC, Mikami A, Minatoguchi S, Fujiwara T, Fujiwara H |
Treatment with granulocyte colony-stimulating factor ameliorates chronic heart failure |
Laboratory Investigation 86, 32-44 (01 Jan 2006) |
SPR-407 |
mouse |
chronic heart failure; cytokines; G-CSF; remodeling; signal transduction |
| Xu J, Kimball TR, Lorenz JN, Brown DA, Bauskin AR, Klevitsky R, Hewett TE, Breit SN, Molkentin JD |
GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation |
Circ. Res., Feb 2006; 98: 342 - 350 |
1.4F Millar catheter |
mouse |
cardiac • signaling • hypertrophy • growth factors • mouse genetics |
| Kempf T, Eden M, Strelau J, Naguib M, Willenbockel C, Tongers J, Heineke J, Kotlarz D, Xu J, Molkentin JD, Niessen HW, Drexler H, . Wollert KC |
The Transforming Growth Factor-ß Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury |
|
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